Chaperonin Containing TCP1, Subunit 2 (Beta) (CCT2) antibody

Details for Product No. ABIN969009
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Antigen
Synonyms fa26a01, fc58a11, CHUNP6883, wu:fa26a01, wu:fc58a11, cct2, MGC89448, CCT2, 99D8.1, CCT-beta, CCTB, PRO1633, TCP-1-beta, Cctb
Reactivity
Human
(43), (23), (22), (14), (14), (14), (14), (5), (3), (2), (2), (2), (1), (1)
Host
Mouse
(24), (17), (8)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(39), (14), (10), (9), (6), (4), (4), (2), (2), (1), (1)
Pubmed 2 references available
Quantity 100 µL
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Catalog No. ABIN969009
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Immunogen Purified recombinant fragment of human CCT2 expressed in E. coli.
Clone 5B5F5
Isotype IgG1
Purification Ascites
Alternative Name CCT2
Background Synonyms:
CCTB, 99D8. 1, PRO1633, CCT-β, MGC142074, MGC142076, TCP-1-β
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Two transcript variants encoding different isoforms have been found for this gene.
Molecular Weight 54 kDa
Gene ID 10576
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
anti-Chaperonin Containing TCP1, Subunit 2 (Beta) (CCT2) antibody Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng)
anti-Chaperonin Containing TCP1, Subunit 2 (Beta) (CCT2) antibody (2) Figure 2: Western blot analysis using CCT2 mouse mAb against Hela (1), MCF-7 (2), Jurkat (3), T47D (4), K562 (5), A431 (6), NIH/3T3 (7), PC-12 (8) and Cos7 (9) cell lysate.
anti-Chaperonin Containing TCP1, Subunit 2 (Beta) (CCT2) antibody (3) Figure 1: Western blot analysis using CCT2 mAb against human CCT2 (AA: 87-290) recombinant protein. (Expected MW is 47.9 kDa)
Product cited in: Goudreault, DAmbrosio, Kean et al.: "A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein." in: Molecular & cellular proteomics : MCP, Vol. 8, Issue 1, pp. 157-71, 2009 (PubMed).

Abe, Yoon, Kubota et al.: "p90 ribosomal S6 kinase and p70 ribosomal S6 kinase link phosphorylation of the eukaryotic chaperonin containing TCP-1 to growth factor, insulin, and nutrient signaling." in: The Journal of biological chemistry, Vol. 284, Issue 22, pp. 14939-48, 2009 (PubMed).

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