MYOD1 antibody

Catalog No. ABIN969305

The Mouse Monoclonal anti-MYOD1 antibody has been validated for ELISA. It is suitable to detect MYOD1 in samples from Human. There are 3+ publications available.

Quick Overview for MYOD1 antibody (ABIN969305)

Target: MYOD1 (Myogenic Differentiation 1 (MYOD1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MYOD1 antibody is un-conjugated

Application: ELISA

Clone: 1C8

Product Details anti-MYOD1 Antibody

Purpose: MYOD1 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human MYOD1 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-MYOD1 antibody (ABIN969305)

Dacwag, Bedford, Sif, Imbalzano: "Distinct protein arginine methyltransferases promote ATP-dependent chromatin remodeling function at different stages of skeletal muscle differentiation." in: Molecular and cellular biology, Vol. 29, Issue 7, pp. 1909-21, (2009) (PubMed).

Yamamoto, Watt, Schmidt, Kuscuoglu, Miesfeld, Goldhamer: "Cloning and characterization of a novel MyoD enhancer-binding factor." in: Mechanisms of development, Vol. 124, Issue 9-10, pp. 715-28, (2007) (PubMed).

Mal: "Histone methyltransferase Suv39h1 represses MyoD-stimulated myogenic differentiation." in: The EMBO journal, Vol. 25, Issue 14, pp. 3323-34, (2006) (PubMed).

Target Details for MYOD1

Target: MYOD1 (Myogenic Differentiation 1 (MYOD1))

Alternative Name: MYOD1

Background: This gene encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis.

Molecular Weight: 34 kDa

Gene ID: 4654

UniProt: P15172

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development