SET Domain, Bifurcated 1 (SETDB1) antibody

Antigen: SET Domain, Bifurcated 1 (SETDB1)

Synonyms: ESET, KG1T, KMT1E, KIAA0067, H3-K9-HMTase4, AU022152, MGC90670, mKIAA0067, SETDB1, NV10069, fc07d03, wu:fc07d03, si:ch211-81a5.6

Clonality: Monoclonal (5H6A12)

Host: Mouse

Reactivity: Human, Mouse (Murine), Monkey

Conjugate: Un-conjugated

Application: ELISA, Immunofluorescence (IF), Western Blotting (WB)

Catalog no.: ABIN969394

Additional Information

Alternative name: SETDB1

Gene ID: 9869

Immunogen: Purified recombinant fragment of human SETDB1 expressed in E. Coli.

Format: Liquid

Isotype: IgG1

Clone: 5H6A12

Description: This gene encodes a histone methyltransferase. The encoded enzyme catalyzes the reaction of S-adenosyl-L-methionine and histone L-lysine to produce S-adenosyl-L-homocysteine and histone N(6)-methyl-L-lysine. The encoded protein likely functions in transcriptional repression. Alternatively spliced transcript variants have been described.
Synonyms: ESET, KG1T, KMT1E, KIAA0067, H3-K9-HMTase4, SETDB1

Molecular Weight: 180kDa

Application Details

Application Notes: Western Blotting: 1/500 - 1/2000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Purification: Ascites

Buffer: Ascitic fluid containing 0.03% sodium azide.

Preservative: 0.03% sodium azide

Storage: Store at 4℃, for long term storage, store at -20℃.

Restrictions: For Research Use only

Publications

Product: Gevaert, Staes, Van Damme et al.: "Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC." in: Proteomics, Vol. 5, Issue 14, pp. 3589-99, 2005 (PubMed).

Rosendorff, Sakakibara, Lu et al.: "NXP-2 association with SUMO-2 depends on lysines required for transcriptional repression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 14, pp. 5308-13, 2006 (PubMed).