SET Domain, Bifurcated 1 (SETDB1) antibody

Details for Product No. ABIN969394
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Antigen
Synonyms SETDB1, NV10069, fc07d03, si:ch211-81a5.6, wu:fc07d03, ESET, H3-K9-HMTase4, KG1T, KMT1E, TDRD21, AU022152, mKIAA0067
Reactivity
Human, Mouse (Murine), Monkey
(77), (27), (17), (8)
Host
Mouse
(54), (23)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB), Immunocytochemistry (ICC)
(66), (36), (14), (10), (9), (7), (6), (5), (3), (3), (3), (1), (1)
Pubmed 2 references available
Quantity 100 μL
Options
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Immunogen Purified recombinant fragment of human SETDB1 expressed in E. coli.
Clone 5H6A12
Isotype IgG1
Purification Ascites
Alternative Name SETDB1 (SETDB1 Antibody Abstract)
Background Synonyms:
ESET, KG1T, KMT1E, KIAA0067, H3-K9-HMTase4, SETDB1
This gene encodes a histone methyltransferase. The encoded enzyme catalyzes the reaction of S-adenosyl-L-methionine and histone L-lysine to produce S-adenosyl-L-homocysteine and histone N (6)-methyl-L-lysine. The encoded protein likely functions in transcriptional repression. Alternatively spliced transcript variants have been described.
Molecular Weight 180 kDa
Gene ID 9869
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, ICC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
anti-SET Domain, Bifurcated 1 (SETDB1) antibody Figure 2: Immunofluorescence analysis of LOVO cells using SETDB1 mouse mAb (green) . ...
anti-SET Domain, Bifurcated 1 (SETDB1) antibody (2) Figure 1: Western blot analysis using SETDB1 mouse mAb against MCF-7 (1) ,T47D (2), H...
Product cited in: Rosendorff, Sakakibara, Lu et al.: "NXP-2 association with SUMO-2 depends on lysines required for transcriptional repression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 14, pp. 5308-13, 2006 (PubMed).

Gevaert, Staes, Van Damme et al.: "Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC." in: Proteomics, Vol. 5, Issue 14, pp. 3589-99, 2005 (PubMed).

Validation Images
Catalog No. ABIN969394
393.80 $
Plus shipping costs $45.00
Quantity
Price
100 μL
393.80 $

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