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Details for Product No. ABIN969517

Eukaryotic Translation Initiation Factor 4B (EIF4B) antibody

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Antigen
Synonyms
EIF-4B, PRO1843, C85189, Eif4a2, AL024095, 2310046H11Rik, CG10837, Dm-eIF4B, Dmel\\CG10837, Eif4B, eIF-4B-L, eIF-4B-S, eIF-4b, eIF4B, eIF4B-L, eIF4B-S, eIf4b, eif4b, fb15c09, wu:fb15c09, zgc:101532, M ... show more
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Fluorescence Microscopy (FM)
Pubmed 2 references available
Catalog no. ABIN969517
Quantity 0.1 mg
Price
396.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 3 to 4 Business Days
Immunogen Purified recombinant fragment of human EIF4B expressed in E. coli.
Clone 1F5
Isotype IgG2b
Purification Purified
Alternative Name EIF4B
Background Synonyms:
EIF-4B, PRO1843
The eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA. It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. It promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both eIF4A and eIF4F
Molecular Weight 80 kDa
Gene ID 1975
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide and 0.5 % protein stabilizer
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Product cited in: Shahbazian, Roux, Mieulet et al.: "The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity." in: The EMBO journal, Vol. 25, Issue 12, pp. 2781-91, 2006 (PubMed).

Mokas, Mills, Garreau et al.: "Uncoupling stress granule assembly and translation initiation inhibition." in: Molecular biology of the cell, Vol. 20, Issue 11, pp. 2673-83, 2009 (PubMed).

Alternatives for antigen "Eukaryotic Translation Initiation Factor 4B (EIF4B)", type "Antibodies"
Hosts (100), (9), (1)
Reactivities (105), (57), (32), (26), (24), (12), (12), (3), (2), (1)
Applications (76), (35), (30), (29), (28), (12), (7), (5), (3)
Conjugates (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3)
Epitopes (28), (14), (4), (4), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
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