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Eukaryotic Translation Initiation Factor 4B (EIF4B) antibody

Antigen

Eukaryotic Translation Initiation Factor 4B (EIF4B)
Synonyms
EIF-4B, PRO1843, Dm-eIF4B, Eif4B, eIF-4B-L, eIF-4B-S, DmelCG10837, CG10837, EIF4B, C85189, Eif4a2, AL024095, 2310046H11Rik, MGC94923, eif4b, fb15c09, MGC101532, wu:fb15c09, zgc:101532, MGC89384, MGC12 ... show more
Clonality Monoclonal (1F5)
Host
Alternatives

Mouse
Reactivity
Alternatives

Human, Mouse (Murine)
Conjugate
Alternatives Un-conjugated
Application
Alternatives ELISA, Flow Cytometry (FACS), Western Blotting (WB)
2 references available
Catalog no. ABIN969517
Quantity 0.1ml
Price 396.00 $   Plus shipping costs $45.00
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Additional Information
Application Details Publications Alternatives back to top

Alternative name EIF4B
Gene ID 1975
Immunogen Purified recombinant fragment of human EIF4B expressed in E. Coli.
Format Liquid
Isotype IgG2b
Clone 1F5
Description The eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA.It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. It promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both eIF4A and eIF4F
Synonyms: EIF-4B, PRO1843
Molecular Weight 80kDa
Synonyms EIF-4B, PRO1843, Dm-eIF4B, Eif4B, eIF-4B-L, eIF-4B-S, DmelCG10837, CG10837, EIF4B, C85189, Eif4a2, AL024095, 2310046H11Rik, MGC94923, eif4b, fb15c09, MGC101532, wu:fb15c09, zgc:101532, MGC89384, MGC127720, DKFZp469D171

Application Details
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Application Notes Western Blotting: 1/500 - 1/2000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Purification Purified
Buffer PBS with 0.05% sodium azide and 0.5% protein stabilizer.
Preservative 0.05% sodium azide
Storage Store at 4℃, for long term storage, store at -20℃.
Restrictions For Research Use only

Publications
Application Details Alternatives back to top

Product Shahbazian, Roux, Mieulet et al.: "The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity." in: The EMBO journal, Vol. 25, Issue 12, pp. 2781-91, 2006 (PubMed).

Mokas, Mills, Garreau et al.: "Uncoupling stress granule assembly and translation initiation inhibition." in: Molecular biology of the cell, Vol. 20, Issue 11, pp. 2673-83, 2009 (PubMed).

Alternatives
Application Details Publications back to top

Alternatives for antigen "Eukaryotic Translation Initiation Factor 4B (EIF4B)", type "Antibodies"
Hosts Rabbit (77), Goat (1), Mouse (1)
Reactivities Human (76), Mouse (Murine) (41), Rat (Rattus) (31), Horse (Equine) (29), Cow (Bovine) (13), Dog (Canine) (11), Guinea Pig (5), Pig (Porcine) (5), Sheep (Ovine) (5), Cat (Feline) (1), Chicken (1)
Applications Western Blotting (WB) (46), Immunofluorescence (IF) (31), ELISA (27), Immunohistochemistry (IHC) (19), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (16), Immunoprecipitation (IP) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Dot Blot (Dot) (1), Flow Cytometry (FACS) (1), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Fluor 350 (3), Alexa Fluor 488 (3), Alexa Fluor 555 (3), Alexa Fluor 647 (3), PE,Cy5.5 (3), Alexa Flour 488 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
Epitopes pSer422 (12), C-Term (5), Ser422 (4), pSer540 (4), Internal Region (2), pSer93 (2), AA 1-200 (1), AA 150-200 (1), AA 500-550 (1), AA 561-611 (1), AA 570-630 (1), Center (1), Center, Ser498 (1), Center,Ser498 (1), Middle Region (1), N-Term (1), pSer406 (1), pSer504 (1), pThr790 (1)