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ZFP36 antibody (N-Term)

The Rabbit Polyclonal anti-ZFP36 antibody (ABIN183636) specifically detects ZFP36 in WB. The antibody is reactive with Human samples.

Rabbit Anti-ZFP36 antibody Paraffin Embedded Tissue: Human Heart cell Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4. (ZFP36 antibody (N-Term))

IHC

2 images

Catalog No. ABIN183636

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Quick Overview for ZFP36 antibody (N-Term) (ABIN183636)

Target

See all ZFP36 Antibodies

ZFP36 (Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36))

Reactivity

Human

Host

Rabbit

Clonality

Polyclonal

Conjugate

This ZFP36 antibody is un-conjugated

Application

Western Blotting (WB)

Discover our top product ZFP36 Primary Antibody

Binding Specificity
8

5

3

2

1

1

1

1

1

1

1

1

1
N-Term

Sequence

MDLTAIYESL LSLSPDVPVP SDHGGTESSP GWGSSGPWSL SPSDSSPSGV

Predicted Reactivity

Human: 100%

Characteristics

This is a rabbit polyclonal antibody against ZFP36. It was validated on Western Blot using a cell lysate as a positive control.

Purification

Affinity Purified

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ZFP36
anti-Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) (AA 119-148) antibody
ZFP36 Reactivity: Human, Mouse WB, FACS, IHC (p) Host: Rabbit Polyclonal RB19979 unconjugated

anti-Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) (N-Term) antibody
ZFP36 Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit, Sheep WB Host: Rabbit Polyclonal unconjugated

anti-Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) antibody
ZFP36 Reactivity: Human, Mouse, Rat ELISA, IHC Host: Rabbit Polyclonal unconjugated

anti-Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) (AA 1-326) antibody
ZFP36 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated

anti-Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) (AA 84-133) antibody
ZFP36 Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit, Sheep, Pig WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) (AA 41-90) antibody
ZFP36 Reactivity: Human WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) (AA 257-306) antibody
ZFP36 Reactivity: Human, Dog, Cow, Guinea Pig, Rabbit, Sheep, Pig, Monkey WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) antibody
ZFP36 Reactivity: Human, Dog, Monkey WB, FACS Host: Mouse Monoclonal 1G9 unconjugated

anti-Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) antibody
ZFP36 Reactivity: Human WB, FACS, IF Host: Mouse Monoclonal 1C8 unconjugated

anti-Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) antibody
ZFP36 Reactivity: Human WB, IHC, FACS, IF Host: Mouse Monoclonal 8B5 unconjugated

Application Notes

Optimal working dilutions should be determined experimentally by the investigator.

Comment

Antigen size: 326 AA

Restrictions

For Research Use only
Format

Liquid

Concentration

Lot specific

Buffer

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice

Avoid repeated freeze-thaw cycles.

Storage

-20 °C

Storage Comment

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target

ZFP36 (Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36))

Alternative Name

ZFP36

Background

ZFP36 is a probable regulatory protein with a novel zinc finger structure involved in regulating the response to growth factors. Knockdown of ZFP36 increased both cognate macrophage gene mRNAs and inflammatory tumor necrosis factor protein release. Overexpression of ZFP36 resulted in decreased levels of the same genes supporting its role in regulating macrophage gene expression. Multiple phosphorylation sites in ZFP36 in mammalian cells were reported. ZFP36 can be phosphorylated by JNK as well as by the other members of the greater MAP kinase family. Gene expression profiling predicts clinical outcome of prostate cancer. Inappropriate ZFP36 production may be one factor that contributes to higher rheumatoid arthritis disease activity.
Alias Symbols: TTP, G0S24, GOS24, TIS11, NUP475, zfp-36, RNF162A
Protein Interaction Partner: YWHAB, PPP2CA, DNAJB1, DCP1B, DHX36, PRR5L, XRN1, UBC, TRAF2, EXOSC6, UPF2, EXOSC8, YWHAQ, TNF, DCP2, EDC3, DCP1A, EDC4, CDK6, APP, LIN28A, SH3KBP1, PABPC1, NCL, MAP3K4, HSPA4, HDAC7, HDAC3, NFKB1, HOXC9, HDAC1, CCDC85B, MAPKAPK2, YWHAG, SFN, HMGB1, NUP21
Protein Size: 326

Molecular Weight

34 kDa

Gene ID

7538

NCBI Accession

NM_003407, NP_003398

UniProt

P26651