Browse our anti-CD11b (ITGAM) Antibodies

Full name:
anti-Integrin alpha M Antibodies (ITGAM)
On are 1053 Integrin alpha M (ITGAM) Antibodies from 33 different suppliers available. Additionally we are shipping CD11b Kits (21) and CD11b Proteins (21) and many more products for this protein. A total of 1100 CD11b products are currently listed.
C3bi, CD11B, CD11b/CD18, CR3, CR3A, F730045J24Rik, Ly-40, MAC-1, Mac-1a, MAC1, MAC1A, MO1A, SLEB6
list all antibodies Gene Name GeneID UniProt
ITGAM 16409  
ITGAM 25021  
ITGAM 3684 P11215

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All available anti-CD11b Antibodies

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Top referenced anti-CD11b Antibodies

  1. Human Monoclonal CD11b Primary Antibody for FACS, IHC (fro) - ABIN118146 : Springer: Adhesion receptors of the immune system. in Nature 1990 (PubMed)
    Show all 18 references for 118146

  2. Human Monoclonal CD11b Primary Antibody for FACS - ABIN118147 : Whiteland, Nicholls, Shimeld, Easty, Williams, Hill: Immunohistochemical detection of T-cell subsets and other leukocytes in paraffin-embedded rat and mouse tissues with monoclonal antibodies. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1995 (PubMed)
    Show all 7 references for 118147

  3. Human Monoclonal CD11b Primary Antibody for FACS - ABIN118143 : Springer, Galfrè, Secher, Milstein: Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens. in European journal of immunology 1978 (PubMed)
    Show all 6 references for 118143

  4. Human Monoclonal CD11b Primary Antibody for Func, FACS - ABIN118516 : Dransfield, Cabañas, Barrett, Hogg: Interaction of leukocyte integrins with ligand is necessary but not sufficient for function. in The Journal of cell biology 1992 (PubMed)
    Show all 5 references for 118516

  5. Human Monoclonal CD11b Primary Antibody for FACS - ABIN118518 : Malhotra, Hogg, Sim: Ligand binding by the p150,95 antigen of U937 monocytic cells: properties in common with complement receptor type 3 (CR3). in European journal of immunology 1986 (PubMed)
    Show all 4 references for 118518

  6. Human Monoclonal CD11b Primary Antibody for FACS - ABIN118515 : Sotiriou, Orlova, Al-Fakhri, Ihanus, Economopoulou, Isermann, Bdeir, Nawroth, Preissner, Gahmberg, Koschinsky, Chavakis: Lipoprotein(a) in atherosclerotic plaques recruits inflammatory cells through interaction with Mac-1 integrin. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006 (PubMed)
    Show all 4 references for 118515

  7. Rat (Rattus) Monoclonal CD11b Primary Antibody for Func, FACS - ABIN120414 : Barclay: The localization of populations of lymphocytes defined by monoclonal antibodies in rat lymphoid tissues. in Immunology 1981 (PubMed)
    Show all 4 references for 120414

  8. Rat (Rattus) Monoclonal CD11b Primary Antibody for FACS, IHC (fro) - ABIN120410 : Aihara, Hall, Pitts, Fukuda, Noble: Altered immunoexpression of microglia and macrophages after mild head injury. in Journal of neurotrauma 1995 (PubMed)
    Show all 3 references for 120410

  9. Human Polyclonal CD11b Primary Antibody for EIA, FACS - ABIN951175 : Gjelstrup, Boesen, Kragstrup, Jørgensen, Klein, Thiel, Deleuran, Vorup-Jensen: Shedding of large functionally active CD11/CD18 Integrin complexes from leukocyte membranes during synovial inflammation distinguishes three types of arthritis through differential epitope exposure. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 2 references for 951175

  10. Human Polyclonal CD11b Primary Antibody for FACS, IHC (p) - ABIN654625 : Lavine, Kovacs, Weinheimer, Mann: Repetitive myocardial ischemia promotes coronary growth in the adult mammalian heart. in Journal of the American Heart Association 2013 (PubMed)

More Antibodies against CD11b Interaction Partners

Mouse (Murine) Integrin alpha M (ITGAM) interaction partners

  1. The single nucleotide polymorphism rs1143678 substitutes Pro(1146) for Ser (show SIGLEC1 Antibodies) in the integrin alphaM cytoplasmic tail generates a noncanonical 14-3-3zeta (show YWHAZ Antibodies) binding site that modulates integrin alphaM(PS)beta2 outside-in signaling

  2. a novel role for CR3 and microglia in brain Abeta (show APP Antibodies) metabolism and defining a potential new therapeutic target in Alzheimer disease.

  3. Oral treatment with the mucosal adjuvant cholera toxin (CT) induces expression of T cell immunoglobulin and mucin domain containing 4 (TIM-4 (show TIMD4 Antibodies)) on a proportion of CD103 (show ITGAE Antibodies)+ CD11b+ dendritic cell (DC) in the intestinal lamina propria (LP).

  4. this study shows that genetic deletion of CD11b confers collagen-induced arthritis susceptibility through IL-6 (show IL6 Antibodies)-mediated Th17 differentiation in C57BL/6 mice, which are normally resistant to this disease

  5. RBC (show CACNA1C Antibodies)-leukocyte interactions are significantly diminished in Mac-1-deficient SCD (show SCD Antibodies) mice, leading to an improvement of blood flow rates and prolonged survival time in a tumor necrosis factor-alpha (show TNF Antibodies) and surgical-trauma-induced VOC model. Mac-1-deletion, however, was not sufficient to reduce SCD (show SCD Antibodies)-related chronic organ damage.

  6. The results indicate that both Mac-1 and alphaDbeta2 support macrophage fusion with Mac-1 playing a dominant role

  7. Intestinal CD103 (show ITGAE Antibodies)(+)CD11b(-) dendritic cells restrain colitis via IFN-gamma-induced (show SAMHD1 Antibodies) anti-inflammatory response in epithelial cells.

  8. CD11b immunophenotyping identifies inflammatory profiles in the mouse and human lungs.

  9. this study demonstrates the feasibility of anti-CD11b antibody mediated noninvasive SPECT/CT imaging of inflammatory leukocytes in murine atherosclerotic plaques

  10. Antigen-specific cytotoxic T lymphocytes target airway CD103 (show ITGAE Antibodies)+ and CD11b+ dendritic cells to suppress allergic inflammation.

Human Integrin alpha M (ITGAM) interaction partners

  1. FRbeta (show FOLR2 Antibodies) as a novel CD11b/CD18 regulator for trafficking and homing of a subset of macrophages on collagen.

  2. this study shows that upregulation of CD11b after stimulation with IL-8 (show IL8 Antibodies) is more pronounced in adults than in neonates, whereas fMLP (show FPR1 Antibodies) induces changes in receptor expression that are of the same magnitude in neutrophils from neonates as from adults

  3. Ingestion of amino acid supplement did not influence CD11b expression.

  4. This metaanalysis indicates that polymorphisms in the pathways of immune complex clearance, such as the FcgammaRIIIa, FcgammaRIIIb, and ITGAM genotypes, are potential susceptibility genes for neuropsychiatric systemic lupus erythematosus.

  5. Monocyte-platelet aggregates and CD11b expression on monocytes and granulocytes are increased in atrial fibrillation patients with proven thrombus formation. They seem to be appropriate biomarkers for stratification of thromboembolic risk in patients with AF.

  6. CD11b immunophenotyping identifies inflammatory profiles in the mouse and human lungs.

  7. There is direct interaction between C3(H2O) and CD11b. Contact-activated C3(H2O) is a novel ligand for CD11b/CD18 that mediates platelet-PMN (show TBCE Antibodies) complex formation and the binding of platelet-derived microparticles to PMNs.

  8. Data show that secreted aspartic protease 2 (Sap2) of Candida albicans inactivates human macrophage complement factor H (factor H (show CFH Antibodies)), factor H (show CFH Antibodies)-receptors CD11b/CD18 and CD11c (show ITGAX Antibodies)/CD18 (show ITGB2 Antibodies).

  9. we confirmed the similarities between epithelial ovarian cancer and fallopian tube, normal and adenocarcinoma using FOLR1 (show FOLR1 Antibodies), FOLR2 (show FOLR2 Antibodies), CD68 (show CD68 Antibodies) and CD11b markers

  10. While total surface expression of CD11b and L-selectin (show SELL Antibodies) on neutrophils was largely unaffected

Cow (Bovine) Integrin alpha M (ITGAM) interaction partners

  1. These data describe the presence of specific pattern recognition receptor transcripts in the mRNA isolated from bovine neutrophil and show a CD11b-/Ca(2 (show CA2 Antibodies)+) dependent ROS (show ROS1 Antibodies) production

  2. The molecular cloning and characterization of CD11b from cattle and its similarities to other species are presented.

Pig (Porcine) Integrin alpha M (ITGAM) interaction partners

CD11b (ITGAM) Antigen Profile

Antigen Summary

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with CD11b (ITGAM)

  • integrin, alpha M (complement component 3 receptor 3 subunit) (ITGAM) antibody
  • integrin alpha M (Itgam) antibody
  • integrin, alpha M (Itgam) antibody
  • integrin, alpha M (complement component 3 receptor 3 subunit) (Itgam) antibody
  • C3bi antibody
  • CD11B antibody
  • CD11b/CD18 antibody
  • CR3 antibody
  • CR3A antibody
  • F730045J24Rik antibody
  • Ly-40 antibody
  • MAC-1 antibody
  • Mac-1a antibody
  • MAC1 antibody
  • MAC1A antibody
  • MO1A antibody
  • SLEB6 antibody

Protein level used designations for ITGAM

MAC-1 alpha subunit , integrin alpha M , integrin alpha-M , CD11 antigen-like family member B , CD11B (p170) , CR-3 alpha chain , Mac-1 alpha , cell surface glycoprotein MAC-1 alpha subunit , cell surface glycoprotein MAC-1 subunit alpha , complement component receptor 3 alpha-a , complement receptor type 3 , leukocyte adhesion receptor MO1 , macrophage antigen alpha , antigen CD11b (p170) , macrophage antigen alpha polypeptide , neutrophil adherence receptor alpha-M subunit , leukocyte integrin alpha-M chain , complement receptor 3 , leukocyte integrin alpha M

454069 Pan troglodytes
16409 Mus musculus
25021 Rattus norvegicus
3684 Homo sapiens
407124 Bos taurus
443217 Ovis aries
397459 Sus scrofa
489928 Canis lupus familiaris
100351865 Oryctolagus cuniculus
100135561 Cavia porcellus
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