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Browse our MBL2 Proteins (MBL2)

Full name:
Mannose-Binding Lectin (Protein C) 2, Soluble Proteins (MBL2)
On www.antibodies-online.com are 32 Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2) Proteins from 10 different suppliers available. Additionally we are shipping MBL2 Antibodies (114) and MBL2 Kits (33) and many more products for this protein. A total of 187 MBL2 products are currently listed.
Synonyms:
Ab2-001, Ab2-011, cMBl, COLEC1, collectin, HSMBPC, L-MBP, MBL, MBL-C, MBL1, mbl2, MBL2D, MBP, MBP-C, MBP1, MBPD, pMBP-27
list all proteins Gene Name GeneID UniProt
MBL2 64668 P08661
MBL2 17195 P41317
MBL2 4153 P11226

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MBL2 Proteins (MBL2) by Origin

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Top referenced MBL2 Proteins

  1. Human MBL2 Protein expressed in CHO Cells - ABIN2002787 : Super, Gillies, Foley, Sastry, Schweinle, Silverman, Ezekowitz: Distinct and overlapping functions of allelic forms of human mannose binding protein. in Nature genetics 1993 (PubMed)
    Show all 6 references for ABIN2002787

  2. Mouse (Murine) MBL2 Protein expressed in Human Cells - ABIN2007253 : Wong, Kojima, Dobó, Ambrus, Sim: Activities of the MBL-associated serine proteases (MASPs) and their regulation by natural inhibitors. in Molecular immunology 2000 (PubMed)
    Show all 5 references for ABIN2007253

  3. Human MBL2 Protein expressed in Escherichia coli (E. coli) - ABIN1098702 : Larsen, Madsen, Sim, Koch, Garred: Disease-associated mutations in human mannose-binding lectin compromise oligomerization and activity of the final protein. in The Journal of biological chemistry 2004 (PubMed)
    Show all 2 references for ABIN1098702

More Proteins for MBL2 Interaction Partners

Mouse (Murine) Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2) interaction partners

  1. Human and murine data together indicate that SP-A, SP-D and MBL are synthesized in early gestational tissues, and may contribute to regulation of immune response at the feto-maternal interface during pregnancy.

  2. These data show that modulation of MBL is involved in the protection against renal I/RI induced by dietary restriction, and suggest that the mechanisms of protection induced by dietary restriction and fasting may be different.

  3. ALI in H5N1-infected mice was caused by excessive complement activation, as demonstrated by deposition of C3, C5b-9, and MBL-C in lung tissue, and by up-regulation of MBL-associated serine protease-2 (show MASP2 Proteins) and the complement receptors C3aR (show C3AR1 Proteins) and C5aR (show C5AR1 Proteins).

  4. demonstrate that apolipoprotein E (Apoe (show APOE Proteins)), mannose-binding lectin 2 (Mbl2), and parotid secretory protein (Psp) are present at significantly different quantities in depleted plasma of diabetic NZO mice compared to non-diabetic controls

  5. Data indicate that no change of mannan-binding lectin MBL-A during the study, however, mannan-binding lectin MBL-C concentration increased in median by 3.6-fold (2.9; 4.5-fold) during the study in the diabetic group.

  6. These observations point to a previously unappreciated role for MBL in regulating host resistance and cardiac inflammation during infection with a major human pathogen.

  7. MBL plays a key role in clearing influenza A virus and maintaining lung homeostasis.

  8. Data show that genetically defined MBL-deficiency is associated with a better outcome after acute stroke.

  9. Recombinant mouse ficolin A, mannose-binding lectin-A, and mannose-binding lectin-C bound to fibrinogen in a dose-dependent manner. The lectin pathway, through mannose-binding lectins, synchronized with blood coagulation.

  10. role for MBL in clearance of dying cells

Human Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2) interaction partners

  1. Polymorphisms of the MBL2 gene is associated with fever episodes in pediatric cancer.

  2. MBL2 and MASP2 (show MASP2 Proteins) deficiencies protect against the development of systemic inflammatory response after pediatric cardiac surgery.

  3. Human and murine data together indicate that SP-A, SP-D and MBL are synthesized in early gestational tissues, and may contribute to regulation of immune response at the feto-maternal interface during pregnancy.

  4. Our meta-analysis of accessible, published data has demonstrated no statistically significant association between MBL2 genotype and recurrent respiratory tract infection in children.

  5. No remarkable associations were detected regarding codon 52, 57, exon 1 and extended genotype of MBL2 with the risk rheumatoid arthritis. Meta-analysis.

  6. Frequent IgG subclass and mannose binding lectin deficiency has been found in patients with chronic fatigue syndrome.

  7. In type 2 diabetic patients with stroke, high levels of MBL predict future functional outcomes and mortality. This indicated that the elevated MBL levels may play a significant role in the pathology of the subsequent damage.

  8. MBL2 functional variants were associated with Visceral Leishmaniasis.

  9. MBL2 haplotype is associated with frequent exacerbations and high serum MBL is linked to increased survival in COPD (show ARCN1 Proteins) patients.

  10. MBL gene codon 54 variant allele B is related to low serum MBL levels, increased IL-6 (show IL6 Proteins) levels, genitourinary infections and may cause pregnancy-related problems such as infertility, recurrent miscarriage and preterm delivery

Pig (Porcine) Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2) interaction partners

  1. MBL2 polymorphisms were associated with some disease groups and with the presence of some etiologic agents

  2. MBL1 was also found to be expressed in the lung, testis and brain, whereas low expression of MBL2 was detected in the testis and kidney.

Cow (Bovine) Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2) interaction partners

  1. Single nucleotide polymorphisms in MBL2 at exon 1 were detected using polymerase chain reaction single-strand conformation polymorphism analysis and DNA sequencing techniques in 825 Chinese Holstein cows.

  2. the relationship between the variants of the bovine MBL2 gene and milk production traits, mastitis, serum MBL-C levels and hemolytic complement activity in both classical pathway (CH50) and alternative pathway (ACH50) in Chinese Holstein cattle

MBL2 Protein Profile

Protein Summary

This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases.

Alternative names and synonyms associated with MBL2

  • mannose-binding lectin (protein C) 2, soluble (MBL2)
  • Mannose-binding protein C (mbl2)
  • mannose-binding lectin (protein C) 2, soluble (opsonic defect) (MBL2)
  • mannose-binding lectin (protein C) 2 (Mbl2)
  • Ab2-001 protein
  • Ab2-011 protein
  • cMBl protein
  • COLEC1 protein
  • collectin protein
  • HSMBPC protein
  • L-MBP protein
  • MBL protein
  • MBL-C protein
  • MBL1 protein
  • mbl2 protein
  • MBL2D protein
  • MBP protein
  • MBP-C protein
  • MBP1 protein
  • MBPD protein
  • pMBP-27 protein

Protein level used designations for MBL2

mannose-binding lectin (protein C) 2, soluble (opsonic defect) , mannose-binding lectin 2, soluble , mannose-binding protein C , Mannose-binding protein C , MBP-C , RA-reactive factor P28A subunit , RARF/P28A , mannan-binding protein , mannose binding lectin 2 (protein C) , mannose-binding protein C (liver) , ra-reactive factor polysaccharide-binding component p28A , raRF p28A , mannose binding lectin (C) , mannose binding lectin, liver (C) , collectin-1 , mannan-binding lectin , mannose-binding lectin 2, soluble (opsonic defect) , MBP1 , soluble mannose-binding lectin , 27 kDa mannan-binding protein monomeric subunit , c-type lectin , mannose binding lectin, liver (A) , mannose-binding lectin 2

GENE ID SPECIES
702652 Macaca mulatta
100196468 Salmo salar
100302094 Ovis aries
64668 Rattus norvegicus
17195 Mus musculus
4153 Homo sapiens
449582 Pan troglodytes
397230 Sus scrofa
281297 Bos taurus
374267 Gallus gallus
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