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Browse our MBL2 Proteins (MBL2)

Full name:
Mannose-Binding Lectin (Protein C) 2, Soluble Proteins (MBL2)
On www.antibodies-online.com are 38 Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2) Proteins from 10 different suppliers available. Additionally we are shipping MBL2 Antibodies (113) and MBL2 Kits (34) and many more products for this protein. A total of 192 MBL2 products are currently listed.
Synonyms:
Ab2-001, Ab2-011, cMBl, COLEC1, collectin, HSMBPC, L-MBP, MBL, MBL-C, MBL1, mbl2, MBL2D, MBP, MBP-C, MBP1, MBPD, pMBP-27
list all proteins Gene Name GeneID UniProt
MBL2 64668 P08661
MBL2 17195 P41317
MBL2 4153 P11226

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MBL2 Proteins (MBL2) by Origin

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Top referenced MBL2 Proteins

  1. Human MBL2 Protein expressed in CHO Cells - ABIN2002787 : Super, Gillies, Foley, Sastry, Schweinle, Silverman, Ezekowitz: Distinct and overlapping functions of allelic forms of human mannose binding protein. in Nature genetics 1993 (PubMed)
    Show all 6 references for ABIN2002787

  2. Mouse (Murine) MBL2 Protein expressed in Human Cells - ABIN2007253 : Wong, Kojima, Dobó, Ambrus, Sim: Activities of the MBL-associated serine proteases (MASPs) and their regulation by natural inhibitors. in Molecular immunology 2000 (PubMed)
    Show all 5 references for ABIN2007253

  3. Human MBL2 Protein expressed in Escherichia coli (E. coli) - ABIN1098702 : Larsen, Madsen, Sim, Koch, Garred: Disease-associated mutations in human mannose-binding lectin compromise oligomerization and activity of the final protein. in The Journal of biological chemistry 2004 (PubMed)
    Show all 2 references for ABIN1098702

More Proteins for MBL2 Interaction Partners

Mouse (Murine) Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2) interaction partners

  1. Targeted deletion of Mbl1/2 causes differential levels of inflammation-related gene sets at baseline and after exposure to ozone and significantly reduces pulmonary inflammation, thus indicating an important innate immunomodulatory role of the Mbl1/2 genes.

  2. Human and murine data together indicate that SP-A, SP-D and MBL are synthesized in early gestational tissues, and may contribute to regulation of immune response at the feto-maternal interface during pregnancy.

  3. These data show that modulation of MBL is involved in the protection against renal I/RI induced by dietary restriction, and suggest that the mechanisms of protection induced by dietary restriction and fasting may be different.

  4. ALI in H5N1-infected mice was caused by excessive complement activation, as demonstrated by deposition of C3, C5b-9, and MBL-C in lung tissue, and by up-regulation of MBL-associated serine protease-2 (show MASP2 Proteins) and the complement receptors C3aR (show C3AR1 Proteins) and C5aR (show C5AR1 Proteins).

  5. demonstrate that apolipoprotein E (Apoe (show APOE Proteins)), mannose-binding lectin 2 (Mbl2), and parotid secretory protein (Psp) are present at significantly different quantities in depleted plasma of diabetic NZO mice compared to non-diabetic controls

  6. Data indicate that no change of mannan-binding lectin MBL-A during the study, however, mannan-binding lectin MBL-C concentration increased in median by 3.6-fold (2.9; 4.5-fold) during the study in the diabetic group.

  7. These observations point to a previously unappreciated role for MBL in regulating host resistance and cardiac inflammation during infection with a major human pathogen.

  8. MBL plays a key role in clearing influenza A virus and maintaining lung homeostasis.

  9. Data show that genetically defined MBL-deficiency is associated with a better outcome after acute stroke.

  10. Recombinant mouse ficolin A, mannose-binding lectin-A, and mannose-binding lectin-C bound to fibrinogen in a dose-dependent manner. The lectin pathway, through mannose-binding lectins, synchronized with blood coagulation.

Human Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2) interaction partners

  1. this study shows that MBL2 polymorphisms is not a major risk factor for community-acquired pneumonia in general, but patients with genotypes corresponding with high serum MBL levels are at risk for atypical pneumonia

  2. MBL-deficient individuals with additional lectin pathway pattern recognition molecular defects may be at risk to morbidity.

  3. MBL2 polymorphisms were associated with an increased and TLR7 (show TLR7 Proteins) polymorphisms with a decreased risk of rhinovirus-associated acute otitis media.

  4. MBL2 rs11003123 polymorphism may be a marker for the risk of hepatocellular carcinoma occurrence in patients with HBV-related cirrhosis in the Chinese population.

  5. this study shows that MBL levels may be linked with the occurrence of spondyloarthritis in Brazilian patients

  6. Low baseline MBL levels were correlated with high risk of gram-negative bacteremia; however, no significant correlation was shown in the follow-up.

  7. These results indicate that the mycobacterial antigen 85 complex is a target for ficolins and mannose-binding lectin.

  8. In type 1 diabetic patient, evaluated serum levels of MBL can be seen as an independent marker of diabetic nephropathy even after correcting for possible confounding factors.

  9. this study shoes that Brazilian patients carrying genotypes or haplotypes of low production of MBL would be more susceptible to dengue haemorrhagic fever

  10. Low MBL serum levels and deficient MBL2 diplotypes were associated with a higher incidence of acute cellular rejection during the first year after kidney transplantation.

Pig (Porcine) Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2) interaction partners

  1. MBL2 polymorphisms were associated with some disease groups and with the presence of some etiologic agents

  2. MBL1 was also found to be expressed in the lung, testis and brain, whereas low expression of MBL2 was detected in the testis and kidney.

Cow (Bovine) Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2) interaction partners

  1. Single nucleotide polymorphisms in MBL2 at exon 1 were detected using polymerase chain reaction single-strand conformation polymorphism analysis and DNA sequencing techniques in 825 Chinese Holstein cows.

  2. the relationship between the variants of the bovine MBL2 gene and milk production traits, mastitis, serum MBL-C levels and hemolytic complement activity in both classical pathway (CH50) and alternative pathway (ACH50) in Chinese Holstein cattle

MBL2 Protein Profile

Protein Summary

This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases.

Alternative names and synonyms associated with MBL2

  • mannose-binding lectin (protein C) 2, soluble (MBL2)
  • Mannose-binding protein C (mbl2)
  • mannose-binding lectin (protein C) 2, soluble (opsonic defect) (MBL2)
  • mannose-binding lectin (protein C) 2 (Mbl2)
  • Ab2-001 protein
  • Ab2-011 protein
  • cMBl protein
  • COLEC1 protein
  • collectin protein
  • HSMBPC protein
  • L-MBP protein
  • MBL protein
  • MBL-C protein
  • MBL1 protein
  • mbl2 protein
  • MBL2D protein
  • MBP protein
  • MBP-C protein
  • MBP1 protein
  • MBPD protein
  • pMBP-27 protein

Protein level used designations for MBL2

mannose-binding lectin (protein C) 2, soluble (opsonic defect) , mannose-binding lectin 2, soluble , mannose-binding protein C , Mannose-binding protein C , MBP-C , RA-reactive factor P28A subunit , RARF/P28A , mannan-binding protein , mannose binding lectin 2 (protein C) , mannose-binding protein C (liver) , ra-reactive factor polysaccharide-binding component p28A , raRF p28A , mannose binding lectin (C) , mannose binding lectin, liver (C) , collectin-1 , mannan-binding lectin , mannose-binding lectin 2, soluble (opsonic defect) , MBP1 , soluble mannose-binding lectin , 27 kDa mannan-binding protein monomeric subunit , c-type lectin , mannose binding lectin, liver (A) , mannose-binding lectin 2

GENE ID SPECIES
702652 Macaca mulatta
100196468 Salmo salar
100302094 Ovis aries
64668 Rattus norvegicus
17195 Mus musculus
4153 Homo sapiens
449582 Pan troglodytes
397230 Sus scrofa
281297 Bos taurus
374267 Gallus gallus
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