Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

COL3 antibody (AA 1301-1400)

This anti-COL3 antibody is a Rabbit Polyclonal antibody detecting COL3 in WB, ELISA, IF (cc), IF (p), IHC (fro) and IHC (p). Suitable for Human, Rat, Mouse, Rabbit and Dog. This Primary Antibody has been cited in 11+ publications.
Catalog No. ABIN669981
$384.62
Plus shipping costs $50.00
100 μL
Shipping to: United States
Delivery in 4 to 6 Business Days

Quick Overview for COL3 antibody (AA 1301-1400) (ABIN669981)

Target

See all COL3 Antibodies
COL3 (Collagen, Type III (COL3))

Reactivity

  • 67
  • 42
  • 40
  • 15
  • 14
  • 1
  • 1
Human, Rat, Mouse, Rabbit, Dog

Host

  • 55
  • 9
  • 8
Rabbit

Clonality

  • 53
  • 19
Polyclonal

Conjugate

  • 29
  • 7
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This COL3 antibody is un-conjugated

Application

  • 60
  • 27
  • 25
  • 25
  • 21
  • 19
  • 16
  • 15
  • 14
  • 10
  • 10
  • 5
  • 2
Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Binding Specificity

    • 15
    • 14
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1301-1400

    Specificity

    This antibody is produced with an immunogen contained within the COLFI propeptide region, it will only recognize the full length Collagen III protein and not the mature form.

    Cross-Reactivity

    Dog, Human, Mouse, Rabbit, Rat

    Predicted Reactivity

    Cow,Chicken

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human Collagen alpha 1(III) chain (C-terminal propeptide)

    Isotype

    IgG
  • Application Notes

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Expiry Date

    12 months
  • Velázquez, Enos, Carson, Cranford, Bader, Sougiannis, Pritchett, Fan, Carson, Murphy: "miR155 deficiency aggravates high-fat diet-induced adipose tissue fibrosis in male mice." in: Physiological reports, Vol. 5, Issue 18, (2018) (PubMed).

    Bai, Wu, Hong, Zhang, Liu, Chen: "Anti‑fibrotic effect of Sedum sarmentosum Bunge extract in kidneys via the hedgehog signaling pathway." in: Molecular medicine reports, Vol. 16, Issue 1, pp. 737-745, (2017) (PubMed).

    Yu, Liu, Sun, Wang, Wang, Zhao, Dai, Zhao, Zhang, Li, Han, Lu, Dong, Liu, Yu, Li: "Chronic obstructive sleep apnea promotes aortic remodeling in canines through miR-145/Smad3 signaling pathway." in: Oncotarget, Vol. 8, Issue 23, pp. 37705-37716, (2017) (PubMed).

    Yang, Zhao, Wang, Liu, Ma, Huang, Liu: "Isolation and biological characterization of tendon-derived stem cells from fetal bovine." in: In vitro cellular & developmental biology. Animal, Vol. 52, Issue 8, pp. 846-56, (2017) (PubMed).

    Zhu, Hu, Yu, Ren, Hu: "High Molecular Weight Hyaluronic Acid Inhibits Fibrosis of Endometrium." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 22, pp. 3438-3445, (2016) (PubMed).

    Jiang, Chun, Wang, Du, Wang, Xiong: "Effect of transforming growth factor-β3 on the expression of Smad3 and Smad7 in tenocytes." in: Molecular medicine reports, Vol. 13, Issue 4, pp. 3567-73, (2016) (PubMed).

    Bai, Lu, Lin, Xu, Hu, Liang, Hong, Chen: "Sonic hedgehog-mediated epithelial-mesenchymal transition in renal tubulointerstitial fibrosis." in: International journal of molecular medicine, Vol. 37, Issue 5, pp. 1317-27, (2016) (PubMed).

    Su, Zhao, Shi, Zhang, Yu, Xie, Guo, Zhang, Liu, Shen, Wang, Li, Zhang, Zhou: "Let-7d suppresses growth, metastasis, and tumor macrophage infiltration in renal cell carcinoma by targeting COL3A1 and CCL7." in: Molecular cancer, Vol. 13, pp. 206, (2016) (PubMed).

    Wang, Li, Huang, Wang: "The influence of hypoxia during different pregnancy stages on cardiac collagen accumulation in the adult offspring." in: BioMed research international, Vol. 2014, pp. 419805, (2015) (PubMed).

    Zhao, Zhang, Chen, Gu, Ni, Shao, Wu, Qin: "Increased expression of NF-AT3 and NF-AT4 in the atria correlates with procollagen I carboxyl terminal peptide and TGF-β1 levels in serum of patients with atrial fibrillation." in: BMC cardiovascular disorders, Vol. 14, pp. 167, (2015) (PubMed).

  • Target

    COL3 (Collagen, Type III (COL3))

    Alternative Name

    Collagen 3

    Background

    Synonyms: EDS4A, Collagen alpha-1(III) chain, COL3A1

    Background: Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of GPR56 in the developing brain and binding to GPR56 inhibits neuronal migration and activates the RhoA pathway by coupling GPR56 to GNA13 and possibly GNA12.

    Gene ID

    1281

    UniProt

    P02461
You are here:
Chat with us!