TCHP antibody (AA 1-498)
Quick Overview for TCHP antibody (AA 1-498) (ABIN7173373)
Target
See all TCHP AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 1-498
-
Cross-Reactivity
- Human
-
Purification
- >95%, Protein G purified
-
Immunogen
- Recombinant Human Trichoplein keratin filament-binding protein (1-498AA)
-
Isotype
- IgG
-
-
anti-Trichoplein, Keratin Filament Binding (TCHP) (AA 291-320) antibody
TCHP Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB24714 unconjugated
anti-Trichoplein, Keratin Filament Binding (TCHP) (C-Term) antibodyTCHP Reactivity: Human ELISA, WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Trichoplein, Keratin Filament Binding (TCHP) (C-Term) antibodyTCHP Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae WB Host: Rabbit Polyclonal unconjugated
anti-Trichoplein, Keratin Filament Binding (TCHP) (AA 306-370), (Middle Region) antibodyTCHP Reactivity: Human WB, FACS, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
anti-Trichoplein, Keratin Filament Binding (TCHP) (AA 387-436) antibodyTCHP Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Bat, Monkey, Pig WB Host: Rabbit Polyclonal unconjugated
anti-Trichoplein, Keratin Filament Binding (TCHP) (C-Term) antibodyTCHP Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
-
-
Application Notes
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:500,
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Preservative
- ProClin
-
Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C,-80 °C
-
Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- TCHP (Trichoplein, Keratin Filament Binding (TCHP))
-
Alternative Name
- TCHP
-
Background
-
Background: Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. May act as a \'capping\' or \'branching\' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells (PubMed:15731013, PubMed:18931701). Is a negative regulator of ciliogenesis (PubMed:25270598).
Aliases: TCHP antibody, Trichoplein keratin filament-binding protein antibody, Protein TCHP antibody, Mitochondrial protein with oncostatic activity antibody, Mitostatin antibody, Tumor suppressor protein antibody
-
UniProt
- Q9BT92
Target
-
