APOBEC3B antibody (N-Term)
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- Target See all APOBEC3B Antibodies
- APOBEC3B (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3B (APOBEC3B))
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Binding Specificity
- N-Term
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Reactivity
- Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This APOBEC3B antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- APOBEC3D/F Antibody detects endogenous levels of total APOBEC3D/F.
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human APOBEC3D/F, corresponding to a region within N-terminal amino acids.
- Isotype
- IgG
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anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3B (APOBEC3B) (AA 299-330), (C-Term) antibody
APOBEC3B Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB1748 unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3B (APOBEC3B) (N-Term) antibodyAPOBEC3B Reactivity: Human, Rat, Zebrafish (Danio rerio), Cow, Horse, Pig, Rabbit WB Host: Rabbit Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3B (APOBEC3B) (AA 1-251) antibodyAPOBEC3B Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3B (APOBEC3B) (AA 78-127) antibodyAPOBEC3B Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3B (APOBEC3B) (AA 1-180) antibodyAPOBEC3B Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3B (APOBEC3B) (AA 299-330) antibodyAPOBEC3B Reactivity: Human, Mouse WB, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- APOBEC3B (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3B (APOBEC3B))
- Alternative Name
- APOBEC3D,APOBEC3F (APOBEC3B Products)
- Synonyms
- A3B antibody, APOBEC1L antibody, ARCD3 antibody, ARP4 antibody, DJ742C19.2 antibody, PHRBNL antibody, bK150C2.2 antibody, APOBEC3B antibody, Apobec3 antibody, Apobec3f antibody, APOBEC3F antibody, APOBEC3Z2 antibody, APOBEC3Z3 antibody, apolipoprotein B mRNA editing enzyme catalytic subunit 3B antibody, APOBEC3B antibody, Apobec3b antibody
- Background
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Description: DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. May inhibit the mobility of LTR and non-LTR retrotransposons.
Gene: APOBEC3D
- Molecular Weight
- 40 kDa
- Gene ID
- 200316
- UniProt
- Q96AK3, Q8IUX4
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