Browse our Glypican 1 Proteins (GPC1)

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Glypican 1 Proteins (GPC1)
On are 14 Glypican 1 (GPC1) Proteins from 6 different suppliers available. Additionally we are shipping Glypican 1 Antibodies (82) and Glypican 1 Kits (38) and many more products for this protein. A total of 136 Glypican 1 products are currently listed.
AI462976, glypican, Glypican-1, GPC1, HSPG M12, HSPGM12, zgc:63947
list all proteins Gene Name GeneID UniProt
GPC1 2817 P35052
GPC1 14733 Q9QZF2
GPC1 58920 P35053

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Glypican 1 Proteins (GPC1) by Origin

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More Proteins for Glypican 1 Interaction Partners

Turkey Glypican 1 (GPC1) interaction partners

  1. Dynamic changes in syndecan-4 (show SDC4 Proteins)- and glypican-1-positive satellite cells indicate that they are differentially expressed during myogenesis.

  2. Glypican-1 regulates myogenic differentiation when it is shed into the extracellular matrix.

  3. These data suggested that expression of the myogenic regulatory transcription factors are dependent upon expression of glypican-1 and syndecan-4 (show SDC4 Proteins) during satellite cell proliferation and differentiation, and Pax7 (show PAX7 Proteins) expression is influenced by glypican-1.

  4. These data suggest that glypican-1 N-glycosylated chains and GAG chains are critical in regulating turkey myogenic satellite cell proliferation, differentiation, and responsivness to FGF2 (show FGF2 Proteins).

  5. syndecan-1 (show SDC1 Proteins), syndecan-4 (show SDC4 Proteins), or glypican-1 differentially affect the processes of turkey muscle cell proliferation and differentiation, and can regulate these developmental stages in an FGF2 (show FGF2 Proteins)-independent manner

Human Glypican 1 (GPC1) interaction partners

  1. Exosomal miR (show MLXIP Proteins) signature is superior to exosomal GPC1 or plasma CA 19-9 levels in establishing a diagnosis of pancreatic ductal carcinoma and differentiating between PDAC and chronic pancreatitis.

  2. The role of glypican-1 in mediating the eNOS (show NOS3 Proteins) activation under shear stress might involve in protecting the endothelial function against disturbed flow.

  3. independent case-control study implicated that common SNPs in GPC1 gene contributed to biliary atresia susceptibility in Chinese population

  4. Data show that notum (show NOTUM Proteins) and glypican-1 and glypican-3 (show GPC3 Proteins) gene expression during colorectal cancer (CRC (show CALR Proteins)) development and present evidence to suggest them as potential new biomarkers of CRC (show CALR Proteins) pathogenesis.

  5. The C terminus is shown to be highly flexible in solution, but it orients the core protein transverse to the membrane, directing a surface evolutionarily conserved in Gpc1 orthologs toward the membrane, where it may interact with signaling molecules

  6. GPC1(+) crExos were detected in the serum of patients with pancreatic cancer with absolute specificity and sensitivity, distinguishing healthy subjects and patients with a benign pancreatic disease in patients with early-and late-stage pancreatic cancer.

  7. GPC1 and FGFR1 (show FGFR1 Proteins) are targets for regulation of their gene expression by miR (show MLXIP Proteins)-149.

  8. DNA from 4 HPV positive and 4 HPV negative fresh frozen primary HNSCC were subject to comprehensive genome-wide methylation profiling.Pathway analysis of 1168 methylated genes showed 8 signal transduction pathways (GPC1) of which 62% are hypermethylated.

  9. We now report that human primary suture mesenchymal cells coexpress GPC1 and GPC3 (show GPC3 Proteins) on the cell surface and release them into the media

  10. Crystal structure of N-glycosylated human glypican-1 core protein shows the structure of two loops evolutionarily conserved in vertebrate glypican-1

Mouse (Murine) Glypican 1 (GPC1) interaction partners

  1. Data show that notum (show NOTUM Proteins) and glypican-1 and glypican-3 (show GPC3 Proteins) gene expression during colorectal cancer (CRC) development and present evidence to suggest them as potential new biomarkers of CRC pathogenesis.

  2. Amyloid precursor protein (APP)/APP-like (show APP Proteins) protein 2 (APLP2 (show APLP2 Proteins)) expression is required to initiate endosome-nucleus-autophagosome

  3. The N-terminal growth-factor-like domain of amyloid-beta precursor protein is necessary for protein-receptor binding, whereas the E2-domain mediates interaction with membrane-anchored syndecan 2 (show SDC2 Proteins) and glypican 1.

  4. Glypican-1 is expressed by neural stem cells and neurons derived from embryonic stem cells, which are then surrounded with cell bodies and processes, which in certain cases show distinctive expression patterns.

  5. Glypican-1 is a novel cellular cofactor for prion (show PRNP Proteins) conversion. It acts as a scaffold facilitating the interaction of PrP(C (show PRNP Proteins)) and PrP(Sc) in lipid rafts.

  6. data imply that endogenous Gpc1 is involved in control of growth factor signaling, a finding that is both novel and relevant to the general question of how the activities of co-receptors are exploited during development

  7. glypican-1 core protein has a specific role in FGF2 (show FGF2 Proteins) signaling. Glypican-1 overexpression may contribute to angiogenesis and the radiation resistance characteristic of this malignancy.

  8. Data describe a relationship between heparan sulfate and copper binding of amyloid precursor protein (APP (show APP Proteins)) and amyloid precursor-like protein 2 (APLP2 (show APLP2 Proteins)) in the modulation of nitroxyl anion-catalyzed heparan sulfate degradation in glypican-1.

  9. cancer cell- and host-derived GPC1 are crucial for full mitogenic, angiogenic, and metastatic potential of cancer cells

  10. GPC1 regulates EC cell cycle progression at least partially by modulating APC (show APC Proteins)/C-mediated degradation of mitotic cyclins and securin (show PTTG1 Proteins)

Cow (Bovine) Glypican 1 (GPC1) interaction partners

  1. Heparan sulfate is involved in both centralized and decentralized glycocalyx-mediated mechanotransduction, with GPC1 acting as a centralized agent and SDC1 (show SDC1 Proteins) functioning in decentralized mechanotransmission. GPC1 mediates NOS3 (show NOS3 Proteins) activation.

Glypican 1 (GPC1) Protein Profile

Protein Summary

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.

Alternative names and synonyms associated with Glypican 1 (GPC1)

  • glypican 1b (gpc1b)
  • glypican 1 (GPC1)
  • glypican 1 (gpc1)
  • glypican 1 (Gpc1)
  • glypican-1-like (LOC100525965)
  • AI462976 protein
  • glypican protein
  • Glypican-1 protein
  • GPC1 protein
  • HSPG M12 protein
  • HSPGM12 protein
  • zgc:63947 protein

Protein level used designations for Glypican 1 Proteins (GPC1)

glypican 1 , glypican-1 , glypican-1-like , glypican proteoglycan 1 , GPI-anchored cell surface heparan sulfate proteoglycan , heparan sulfate proteoglycan core protein

393995 Danio rerio
693243 Meleagris gallopavo
698326 Macaca mulatta
743150 Pan troglodytes
779769 Xenopus (Silurana) tropicalis
100027706 Monodelphis domestica
100445162 Pongo abelii
2817 Homo sapiens
14733 Mus musculus
486197 Canis lupus familiaris
58920 Rattus norvegicus
518114 Bos taurus
100734179 Cavia porcellus
424770 Gallus gallus
101104709 Ovis aries
100525965 Sus scrofa
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