GPC1 Protein (His tag)
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- Target See all GPC1 Proteins
- GPC1 (Glypican 1 (GPC1))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Mouse
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Source
- Human Cells
- Purification tag / Conjugate
- This GPC1 protein is labelled with His tag.
- Purpose
- Recombinant Mouse Glypican-1/GPC1 Protein (His Tag)(Active)
- Sequence
- Asp24-Ser529
- Characteristics
- Recombinant Mouse Glypican-1 is produced by our Mammalian expression system and the target gene encoding Asp24-Ser529 is expressed with a 6His tag at the C-terminus.
- Purity
- > 90 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Human FGFb(Cat: PKSH032437) at 2μg/ml(100 μl/well) can bind Mouse GPC1-His. The ED50 of Mouse GPC1-His is 786 ng/ml .
- Top Product
- Discover our top product GPC1 Protein
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Glypican 1 (GPC1) (AA 24-530) protein (His tag)
GPC1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Glypican 1 (GPC1) (AA 24-529) protein (His tag)GPC1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Glypican 1 (GPC1) (AA 24-131) protein (GST tag)GPC1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Glypican 1 (GPC1) (AA 71-165) protein (GST tag)GPC1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Glypican 1 (GPC1) (AA 24-530) protein (His tag)Crystallography grade GPC1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Glypican 1 (GPC1) (AA 24-529) protein (His tag)Crystallography grade GPC1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Glypican 1 (GPC1) (AA 24-529) (Active) protein (His tag)GPC1 Origin: Mouse Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Glypican 1 (GPC1) (AA 24-530) (Active) protein (His tag)GPC1 Origin: Human Host: HEK-293 Cells Recombinant >85 % as determined by SDS-PAGE. Active
Glypican 1 (GPC1) (AA 24-530) (Active) protein (Fc Tag)GPC1 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- GPC1 (Glypican 1 (GPC1))
- Alternative Name
- Glypican-1/GPC1 (GPC1 Products)
- Synonyms
- gpc1 Protein, zgc:63947 Protein, GPC1 Protein, Glypican-1 Protein, glypican Protein, AI462976 Protein, HSPG M12 Protein, HSPGM12 Protein, glypican 1b Protein, glypican 1 Protein, gpc1b Protein, GPC1 Protein, gpc1 Protein, Gpc1 Protein
- Background
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Background: Glypican-1 is a cell membrane protein and belongs to the glypican family. The protein may act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. It is required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling.
Synonym: Glypican-1,Gpc1
- Molecular Weight
- 56.7 kDa
- UniProt
- Q9QZF2
- Pathways
- Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation
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