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Human NPPB Protein expressed in Escherichia coli (E. coli) - ABIN666711
Harada, Fujita, Miyamoto, Kimura, Maruyama, Furia, Miyata, Taniguchi: Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes. in Cell 1989
Show all 2 references for ABIN666711
Human NPPB Protein expressed in Wheat germ - ABIN1312892
Shaw, Fildes, Pucha?ka, Basith, Yonan, Williams: BNP directly immunoregulates the innate immune system of cardiac transplant recipients in vitro. in Transplant immunology 2008
CNP and BNP serve as oocyte maturation inhibitor to inhibit oocyte maturation in mammals
ANP and BNP gene expression differs considerably between cardiac chambers in the first 72 hours of life in healthy piglets, resembling the transition from fetal to neonate circulation. The cardiac gene expression does not explain plasma concentrations.
Up-regulation of BNP and a reduction in a ratio of sarcoplasmic reticulum calcium ATPase 2a in failing myocardium are observed in a porcine model of tachycardia.
Data show that all five molecules, BNP, ICAM-1 (show ICAM1 Proteins), TNF-alpha (show TNF Proteins), VCAM-1 (show VCAM1 Proteins) and IL-6 (show IL6 Proteins), quickly and reliably signaled adverse interactions.
identification and characterization of a novel alternatively spliced variant of porcine and human NPPB (show BNP Proteins) resulting from exon 2 skipping
Arial natriuretic factor (ANF (show HESX1 Proteins)) and N-terminal proANF may be better suited than brain natriuretic peptide (show BNP Proteins) as markers of cardiac preload during the development and treatment of acute heart failure.
Regional differences in BNP and CNP (show NPPC Proteins) expression were observed in myocardium with sustained left ventricular dyssynchronous contraction.
N-terminal pro-brain natriuretic peptide (show BNP Proteins) may be an important marker for cardiac dysfunction in patients with chronic liver failure in accordance with Child-Pugh stage.
The combination of a clinical model with copeptin (show AVP Proteins) and NTproBNP, which are available in the Emergency Department, is able to prognose early mortality in patients with an episode of Acute Heart Failure.
Blood concentration of BNP is a useful biomarker in the diagnosis of acute heart failure.
Both NT-proANP and NT-proBNP levels were higher in coronary artery disease patients experiencing MACEs following percutaneous coronary intervention in a non-primary setting. Notably, only NT-proANP levels significantly affected prognosis after PCI (show SERPINA5 Proteins).
BNP was statistically significantly higher in patients with nasal polyps than in controls.
Among persons occupationally exposed to lead, certain relationships were demonstrated between rs632793, rs198388 and rs198389 polymorphisms of NPPB (show BNP Proteins) gene and principal toxicological parameters characterizing exposure to lead
In patients with NSTE-ACS, NT-proBNP and the GRACE risk score (but not the TIMI risk score) both have good and comparable predictive value for 30-day mortality.
The NPPB (show BNP Proteins) gene polymorphism is associated with modulation of left ventricular mass in newborns. The NPPA (show NPPA Proteins) and NPPB (show BNP Proteins) gene polymorphisms are associated with blood pressure in newborns.
High plasma BNP levels and left ventricular wall motion abnormalities in the segments perfused with left anterior descending coronary artery or right coronary artery show a high risk for cardioembolic stroke in patients with old myocardial infarction.
we have validated a novel gene, Myh14, as a negative regulator of ISO-induced left ventricular mass hypertrophy in an in vivo mouse model and demonstrated the up-regulation of immediate early gene Myc, fetal gene Nppb, and fibrosis gene Lgals3 in ISO-treated Myh14 deficient hearts compared to controls.
P2X3 (show P2RX3 Proteins) receptors on mouse trigeminal ganglion neurons are subjected to contrasting modulation by inhibitory brain natriuretic peptide (show BNP Proteins) and facilitatory calcitonin gene-related peptide (show CALCA Proteins) that both operate via complex intracellular signaling.
mouse trigeminal neurons endogenous BNP acts on NPR-A (show NPR1 Proteins) receptors to determine constitutive depression of P2X3 (show P2RX3 Proteins) receptor function. Tonic inhibition of P2X3 (show P2RX3 Proteins) receptor activity by BNP/NPR-A (show NPR1 Proteins)/PKG (show PRKG1 Proteins) pathways occurs via two distinct mechanisms: P2X3 (show P2RX3 Proteins) serine phosphorylation and receptor redistribution to non-raft membrane compartments
The findings demonstrated a substantial role of mitochondrial dysfunction in mediating the downregulation of NKCC2 and ENaCalpha in obstructive kidney disease, possibly via iNOS-derived nitric oxide and BNP.
Data (including data from studies in knockout mice) suggest expression of ANP (show NPPA Proteins)/BNP/GC-A (show GUCA1A Proteins) (atrial natriuretic peptide (show NPPA Proteins), brain natriuretic peptide (show BNP Proteins), and guanylyl cyclase-A (show NPR1 Proteins)) is important in embryonic neovascularization and organogenesis.
Goalpha plays a role in ANF sorting during intracellular vectorial transport and with the presence of a mechanism that preserves the molar relationship between cellular ANF and BNP.
The RNA-Seq demonstrates that NPPB (show BNP Proteins) which well activates natriuretic peptide receptor 1 (NPR1 (show NPR1 Proteins)), is well expressed in mouse dorsal root ganglian.
a slow modulatory action by BNP on TRPV1 (show TRPV1 Proteins) and P2X3 (show P2RX3 Proteins) receptors outlining the role of this peptide as a negative regulator of trigeminal sensory neuron excitability to nociceptive stimuli
Natriuretic peptides buffer renin (show REN Proteins)-dependent hypertension.
BNP-NPRA (show NPR1 Proteins) signaling is involved in both itch and pain and does not function upstream of the GRP (show UCMA Proteins)-GRPR (show GRPR Proteins) dedicated neuronal pathway.
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.
gamma-brain natriuretic peptide
, natriuretic peptides B
, brain type natriuretic peptide
, natriuretic peptide precursor B
, natriuretic protein
, brain natriuretic peptide
, Brain natriuretic factor
, natriuretic peptide precursor type B
, Gamma-brain natriuretic peptide