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Browse our anti-SMAD7 (SMAD7) Antibodies

Full name:
anti-SMAD, Mothers Against DPP Homolog 7 Antibodies (SMAD7)
On www.antibodies-online.com are 79 SMAD, Mothers Against DPP Homolog 7 (SMAD7) Antibodies from 21 different suppliers available. Additionally we are shipping SMAD7 Kits (44) and SMAD7 Proteins (5) and many more products for this protein. A total of 134 SMAD7 products are currently listed.
Synonyms:
CRCS3, madh7, MADH8, Smad7a, Smad10, xsmad7
list all antibodies Gene Name GeneID UniProt
SMAD7 4092 O15105
SMAD7 17131 O35253
SMAD7 81516 O88406

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Most Popular Reactivities for anti-SMAD7 (SMAD7) Antibodies

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anti-Human SMAD7 Antibodies:

anti-Mouse (Murine) SMAD7 Antibodies:

anti-Rat (Rattus) SMAD7 Antibodies:

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Top referenced anti-SMAD7 Antibodies

  1. Human Monoclonal SMAD7 Primary Antibody for IHC (p), ELISA - ABIN517666 : Chen, Yang, Huang, Hsue, Lin et al.: Aberrant expression in multiple components of the transforming growth factor-?1-induced Smad signaling pathway during 7,12-dimethylbenz[a]anthracene-induced hamster buccal-pouch squamous-cell ... in Oral oncology 2011 (PubMed)

  2. Human Polyclonal SMAD7 Primary Antibody for WB - ABIN2779418 : Briones-Orta, Sosa-Garrocho, Moreno-Alvarez, Fonseca-Sánchez, Macías-Silva: SnoN co-repressor binds and represses smad7 gene promoter. in Biochemical and biophysical research communications 2006 (PubMed)

  3. Dog (Canine) Polyclonal SMAD7 Primary Antibody for WB - ABIN2779417 : Komuro, Imamura, Saitoh, Yoshida, Yamori, Miyazono, Miyazawa: Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1). in Oncogene 2004 (PubMed)

More Antibodies against SMAD7 Interaction Partners

Human SMAD, Mothers Against DPP Homolog 7 (SMAD7) interaction partners

  1. Results showed that SMAD7 was up-regulated in hepatocellular carcinoma tissues and was found to be the target of UPF1 (show UPF1 Antibodies).

  2. The expression of Smad7 increased.

  3. MiR (show MLXIP Antibodies)-185-3p and miR (show MLXIP Antibodies)-324-3p can modulate NPC (show NPC1 Antibodies) cell growth and apoptosis, at least partly through targeting SMAD7.

  4. Meta-analysis showed that for SMAD7 gene, rs4939827 and rs4464148 are risk factors for colorectal cancer (CRC (show CALR Antibodies)) among Caucasians whereas rs12953717 could elevate the susceptibility to CRC (show CALR Antibodies) in both Caucasians and Asians.

  5. The decrease in miR-195 led to an increase in Smad7 expression and corresponding up-regulation of p65 and the AP-1 (activator protein 1) pathway, which might explain the mechanism of steroid resistance in ulcerative colitis patients

  6. TGF-beta (show TGFB1 Antibodies)/Smad (show SMAD1 Antibodies) signalling pathway and VEGF-A (show VEGFA Antibodies) participate in the pathogenesis of sarcoidosis.

  7. Increased miR-16 (show GDE1 Antibodies) expression promotes liver fibrosis through downregulation of HGF (show HGF Antibodies) and Smad7 in hepatitis C patients.

  8. miR (show MLXIP Antibodies)-181a promotes TGF-beta (show TGFB1 Antibodies)-mediated epithelial-to-mesenchymal transition via repression of Smad7.

  9. Results suggest that Itch is a positive regulator of the TGF-beta (show TGFB1 Antibodies)-mediated Smad (show SMAD1 Antibodies) signaling pathway via Smad7 ubiquitination and protein degradation.

  10. Overexpression of Smad7 in human HaCaT keratinocyte cells and mouse skin tissues elevated EGF receptor (EGFR (show EGFR Antibodies)) activity by impairing ligand-induced ubiquitination and degradation of activated receptor, which is induced by the E3 ubiquitin ligase (show MUL1 Antibodies) c-Cbl (show CBL Antibodies).

Mouse (Murine) SMAD, Mothers Against DPP Homolog 7 (SMAD7) interaction partners

  1. Hic-5 (show TGFB1I1 Antibodies) deficiency attenuates the activation of hepatic stellate cells and liver fibrosis though reducing the TGF-beta (show TGFB1 Antibodies)/Smad2 (show SMAD2 Antibodies) signaling by upregulation of Smad7

  2. Data show that microRNA miR (show MLXIP Antibodies)-21 was significantly upregulated by bone morphogenetic protein 9 (BMP9 (show GDF2 Antibodies)) during the osteogenesis the multilineage cells (MMCs) by suppressing Smad7 protein.

  3. Genetic disruption of Smad7 impairs skeletal muscle growth and regeneration

  4. The present study also identified for the first time, to the best of our knowledge, the promotion of osteogenic differentiation and mineralization by miR (show MLXIP Antibodies)-21, by repressing the expression of Smad7.

  5. Overexpression of Smad7 in human HaCaT keratinocyte cells and mouse skin tissues elevated EGF receptor (EGFR (show EGFR Antibodies)) activity by impairing ligand-induced ubiquitination and degradation of activated receptor, which is induced by the E3 ubiquitin ligase (show MUL1 Antibodies) c-Cbl (show CBL Antibodies).

  6. Smad7 signaling is repressed by the active form of vitamin D, 1,25-dihydroxyvitamin D3, which also activates ERK (show EPHB2 Antibodies) to inhibit the differentiation of an inflammatory T helper cell subset and suppress experimental autoimmune encephalomyelitis

  7. Study identified miR (show MLXIP Antibodies)-367 as a negative regulator of Smad7 expression in pancreatic cancer cells by directly targeting its 3'-UTR (show UTS2R Antibodies).

  8. TGF-beta (show TGFB1 Antibodies) dependent modulation of neurogenesis in aged S7DeltaEx1 animals abrogates the cell-intrinsic hyperproliferative properties

  9. The results indicate that partial loss of Smad7 function in mice leads to compromised bone formation and enhanced bone resorption. Thus, Smad7 is acknowledged as a novel key regulator between osteogenesis and osteoclastogenesis.

  10. Suggest novel role of leptin (show LEP Antibodies)-NADPH oxidase (show NOX1 Antibodies) induction of miR21 as a key regulator of TGF-beta (show TGFB1 Antibodies) signaling and fibrogenesis in experimental and human NASH (show SAMSN1 Antibodies).

Xenopus laevis SMAD, Mothers Against DPP Homolog 7 (SMAD7) interaction partners

  1. cTid1 can bind to other members of the Smad (show SMAD1 Antibodies) family and that highest binding activity occurs with the negative regulatory Smad7, through the conserved MH2 (show SCN4A Antibodies) domain

  2. Smad7 has a role in Xenopus mesodermal and neural induction

Pig (Porcine) SMAD, Mothers Against DPP Homolog 7 (SMAD7) interaction partners

  1. MiR (show MYLIP Antibodies)-92a inhibits porcine ovarian granulosa cell apoptosis by targeting Smad7 gene

Cow (Bovine) SMAD, Mothers Against DPP Homolog 7 (SMAD7) interaction partners

  1. a detailed computational model for TGF-beta (show TGFB1 Antibodies) signalling that incorporates elements of previous models together with crosstalking between Smad1 (show SMAD1 Antibodies)/5/8 and Smad2 (show SMAD2 Antibodies)/3 channels through a negative feedback loop dependent on Smad7.

  2. Results suggest that myostatin (show MSTN Antibodies) auto-regulates its gene expression through a Smad7 dependent mechanism in myogenic cells.

SMAD7 Antigen Profile

Antigen Summary

The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with SMAD7

  • SMAD family member 7 (SMAD7) antibody
  • SMAD family member 7 (Smad7) antibody
  • SMAD family member 7 (smad7) antibody
  • CRCS3 antibody
  • madh7 antibody
  • MADH8 antibody
  • Smad7a antibody
  • Smad10 antibody
  • xsmad7 antibody

Protein level used designations for SMAD7

MAD (mothers against decapentaplegic, Drosophila) homolog 7 , MAD homolog 8 , Mothers against decapentaplegic, drosophila, homolog of, 7 , SMAD, mothers against DPP homolog 7 , hSMAD7 , mothers against DPP homolog 8 , mothers against decapentaplegic homolog 7 , MAD homolog 7 , SMAD 7 , madh8 , mothers against DPP homolog 7 , mothers against decapentaplegic homolog 8 , MAD, mothers against decapentaplegic homolog 7 , mothers against DPP 7 , mothers against decapentaplegic-like protein 7 , SMAD family member 7

GENE ID SPECIES
4092 Homo sapiens
17131 Mus musculus
81516 Rattus norvegicus
490570 Canis lupus familiaris
394331 Xenopus laevis
455411 Pan troglodytes
100717293 Cavia porcellus
100521305 Sus scrofa
535916 Bos taurus
429683 Gallus gallus
443160 Ovis aries
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