Browse our anti-NCOA1 (NCOA1) Antibodies

Full name:
anti-Nuclear Receptor Coactivator 1 Antibodies (NCOA1)
On are 121 Nuclear Receptor Coactivator 1 (NCOA1) Antibodies from 22 different suppliers available. Additionally we are shipping NCOA1 Proteins (9) and NCOA1 Kits (6) and many more products for this protein. A total of 140 NCOA1 products are currently listed.
bHLHe42, bHLHe74, c-src, C-src1, CG7524, csrc, D-src, D-Src64B, DKFZp459C083, Dmel\CG7524, DmHD-358, Dm SRC1, dsrc, Dsrc64, Dsrc64B, F-SRC-1, HD-358, KAT13A, MGC128615, MRE5, NCOA1, pp60c-src, pp60v-src, RIP160, si:dkey-5g7.6, si:dkey-34f16.6, SRA1, src, src-1, src1, src2, src64, SRC 64B, src64b, xsrc, zgc:86613
list all antibodies Gene Name GeneID UniProt
NCOA1 8648 Q15788
NCOA1 17977 P70365
NCOA1 313929  

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Top referenced anti-NCOA1 Antibodies

  1. Human Polyclonal NCOA1 Primary Antibody for EIA, WB - ABIN358229 : Encinas, Crowder, Milbrandt, Johnson: Tyrosine 981, a novel ret autophosphorylation site, binds c-Src to mediate neuronal survival. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 references for 358229

  2. Human Polyclonal NCOA1 Primary Antibody for IHC (p), WB - ABIN197376 : Parker, Mardon, Lebo, Varmus, Bishop: Isolation of duplicated human c-src genes located on chromosomes 1 and 20. in Molecular and cellular biology 1985 (PubMed)
    Show all 4 references for 197376

  3. Human Polyclonal NCOA1 Primary Antibody for EIA, IHC (p) - ABIN359992 : Lopez, Carron, Ghysdael: v-SRC specifically regulates the nucleo-cytoplasmic delocalization of the major isoform of TEL (ETV6). in The Journal of biological chemistry 2003 (PubMed)
    Show all 4 references for 359992

  4. Human Polyclonal NCOA1 Primary Antibody for IHC (p), WB - ABIN196876 : Pyper, Bolen: Identification of a novel neuronal C-SRC exon expressed in human brain. in Molecular and cellular biology 1990 (PubMed)
    Show all 4 references for 196876

  5. Human Monoclonal NCOA1 Primary Antibody for BI, WB - ABIN968842 : Oñate, Tsai, Tsai, OMalley: Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. in Science (New York, N.Y.) 1995 (PubMed)
    Show all 4 references for 968842

  6. Amphibian Polyclonal NCOA1 Primary Antibody for FACS, ICC - ABIN152700 : Rogatsky, Zarember, Yamamoto: Factor recruitment and TIF2/GRIP1 corepressor activity at a collagenase-3 response element that mediates regulation by phorbol esters and hormones. in The EMBO journal 2001 (PubMed)
    Show all 3 references for 152700

  7. Human Polyclonal NCOA1 Primary Antibody for EIA, WB - ABIN953617 : Son, Lee: Molecular determinants of the interactions between SRC-1 and LXR/RXR heterodimers. in FEBS letters 2010 (PubMed)
    Show all 3 references for 953617

  8. Human Polyclonal NCOA1 Primary Antibody for WB - ABIN151779 : Heemers, Regan, Schmidt, Anderson, Ballman, Tindall: Androgen modulation of coregulator expression in prostate cancer cells. in Molecular endocrinology (Baltimore, Md.) 2009 (PubMed)

  9. Human Polyclonal NCOA1 Primary Antibody for EIA, IHC (p) - ABIN358230 : Varrin-Doyer, Vincent, Cavagna, Auvergnon, Noraz, Rogemond, Honnorat, Moradi-Améli, Giraudon: Phosphorylation of collapsin response mediator protein 2 on Tyr-479 regulates CXCL12-induced T lymphocyte migration. in The Journal of biological chemistry 2009 (PubMed)

  10. Cow (Bovine) Polyclonal NCOA1 Primary Antibody for WB - ABIN2778219 : Lavery, McEwan: Functional characterization of the native NH2-terminal transactivation domain of the human androgen receptor: binding kinetics for interactions with TFIIF and SRC-1a. in Biochemistry 2008 (PubMed)

More Antibodies against NCOA1 Interaction Partners

Xenopus laevis Nuclear Receptor Coactivator 1 (NCOA1) interaction partners

  1. The structural and functional competency of the UPIII (show UPK3A Antibodies)-Src (show SRC Antibodies) signaling system in membrane microdomains is strictly regulated during oocyte maturation.

Human Nuclear Receptor Coactivator 1 (NCOA1) interaction partners

  1. miR (show MLXIP Antibodies)-4443 acts in a tumor-suppressive manner by down-regulating TRAF4 (show TRAF4 Antibodies) and NCOA1 downstream of MEK (show MAP2K1 Antibodies)-C/EBP (show CEBPA Antibodies)-mediated leptin (show LEP Antibodies) and insulin (show INS Antibodies) signaling, and that insulin (show INS Antibodies) and/or leptin (show LEP Antibodies) resistance (e.g. in obesity) may suppress this pathway and increase the risk of metastatic CRC (show CALR Antibodies).

  2. Results provide the first evidence that NCOA1 is a direct target of miR (show MLXIP Antibodies)-105-1 suggesting that NCOA1 and miR (show MLXIP Antibodies)-105-1 may have potential prognostic value and may be useful as tumor biomarkers for the diagnosis of HCC (show FAM126A Antibodies) patients.

  3. Data suggest that steroid receptor (show ESR2 Antibodies) coactivators (NCOA1, NCOA2 (show NCOA2 Antibodies), NCOA3 (show NCOA3 Antibodies)) are over-expressed in a number of hormone-dependent cancers where they promote tumor growth, invasion, metastasis, and chemo-resistance; with their multiple roles in cancer, steroid receptor (show ESR2 Antibodies) coactivators are promising targets for development of antineoplastic agents that can interfere with their function. [REVIEW]

  4. The mechanism of IL-6-induced AR activation is mediated through enhancing AR-SRC-1 interaction and inhibiting AR-SMRT interaction.

  5. IL-6-mediated AR antagonism induced by cypermethrin is related to repress the recruitment of co-regulators SRC-1 and SMRT to the AR in a ligand-independent manner

  6. NCOA1 potentiates breast cancer angiogenesis through upregulating HIF1alpha (show HIF1A Antibodies) and AP-1 (show FOSB Antibodies)-mediated VEGFa (show VEGFA Antibodies) expression

  7. miR (show MLXIP Antibodies)-137 has a role in targeting p160 (show MSH6 Antibodies) steroid receptor (show ESR2 Antibodies) coactivators SRC1 (show SRC Antibodies), SRC2 (show NCOA2 Antibodies), and SRC3 (show NCOA3 Antibodies) and inhibits cell proliferation

  8. Report novel PAX3 (show PAX3 Antibodies)-NCOA1 gene fusions in biphenotypic sinonasal sarcomas with focal rhabdomyoblastic differentiation.

  9. Data indicate that finerenone inhibits mineralocorticoid receptor (show NR3C2 Antibodies) (MR), steroid receptor coactivator-1 binding at the regulatory sequence.

  10. Data suggest that over-stimulating the steroid seceptor coactivators SRC-1 (show SRC Antibodies), SRC-2 (show NCOA2 Antibodies), and SRC-3 (show NCOA3 Antibodies) oncogenic program can be an effective strategy to kill cancer cells.

Mouse (Murine) Nuclear Receptor Coactivator 1 (NCOA1) interaction partners

  1. The results suggest that biochanin A activates RORgamma-dependent IL-17 (show IL17A Antibodies) transcription through the enhancement of STAT3 (show STAT3 Antibodies) phosphorylation and STAT3 (show STAT3 Antibodies)-mediated recruitment of NCOA1 to RORgamma.

  2. ubiquitination of K446 limits RORgammat-mediated Th17 differentiation by inhibiting the recruitment of coactivator SRC1

  3. Loss of SRC-1 is associated with high Blood Pressure and Aortic Stiffness.

  4. local E2 inhibition could induce aberrant actin polymerization and also showed an important role of SRC-1 in the mediation of local E2 action on hippocampal synaptic plasticity by regulation of actin cytoskeleton dynamics

  5. SRC-1/3 are required for cardiomyocyte proliferation and differentiation at earlier developmental stages, and their dysfunction causes NCC (show SLC12A3 Antibodies)-like abnormalities in the hearts of newborn and adult mice.

  6. While hippocampal SRC-1 was significantly downregulated by orchidectomy (ORX), its expression was rescued by treatment with testosterone in a dose-dependent manner. Testosterone regulates synaptic proteins involves AR, estrogen receptors and SRC-1.

  7. fetal lungs produce signals to initiate labor when mature, and SRC-1/-2-dependent production of SP-A (show SFTPA1 Antibodies) and PAF (show KIAA0101 Antibodies) is crucial for this process

  8. Consequently, SRC-1 null mice displayed low TAT (show TAT Antibodies) expression and presented with hypertyrosinemia and corneal alterations, 2 clinical features observed in the human syndrome of TAT (show TAT Antibodies) deficiency.

  9. the effect of orchidectomy (ORX) on the expression of SRC-1

  10. Letrozole induces dramatic decrease of SRC-1 in the medial septal, hippocampus, medial habenular nucleus, arcuate hypothalamic nucleus and superior colliculus.

Pig (Porcine) Nuclear Receptor Coactivator 1 (NCOA1) interaction partners

  1. we cloned and sequenced full length cDNA of NCOA-1 gene in pig. The putative protein includes 1440 amino acids. Sequences alignment showed that pig NCOA-1 gene cDNA sequence has identity of 93.73% with human and mouse.

Fruit Fly (Drosophila melanogaster) Nuclear Receptor Coactivator 1 (NCOA1) interaction partners

  1. Src64 controls actin dynamics to mediate proper ring canal formation during incomplete cytokinesis during germline cyst development in vivo

  2. that Brat represses the translation of src64B, an upstream regulator of a conserved Rho-dependent pathway previously shown to promote axon retraction

  3. Results show that Src42a and Src64b are required for the normal division capacity of Drosophila intestinal progenitor cells, and that these genes as well as Ack cause progenitor overproliferation in the intestine via core cell cycle activation.

  4. a novel essential role for Src (show SRC Antibodies) in intestinal stem/progenitor cell proliferation and tumourigenesis initiation in vivo.

  5. Data show that the actin-Capping Protein (show TMOD4 Antibodies) (CP) alphabeta heterodimer, which regulates actin (show ACTB Antibodies) filament (F-actin (show ACTB Antibodies)) polymerization, limits Src (show SRC Antibodies)-induced apoptosis or tissue overgrowth by restricting JNK (show MAPK8 Antibodies) activation.

  6. Dumbfounded/Neph1 (show NEPH1 Antibodies), a key diaphragm constituent, is a target of the Src kinase (show CSK Antibodies) Src64B. Loss of Src64B activity leads to a reduction in the number of diaphragms, and this effect is in part mediated by loss of Dumbfounded/Neph1 (show NEPH1 Antibodies) tyrosine phosphorylation.

  7. Homodimerization of the Wnt receptor DERAILED recruits the Src (show SRC Antibodies) family kinase SRC64B in the developing embryonic central nervous system.

  8. E4orf4 has a role in inducing PP2A (show PPP2R2B Antibodies)- and Src (show SRC Antibodies)-dependent cell death while inhibiting classic apoptosis pathways in Drosophila melanogaster

  9. Mutations in a Drosophila src gene, src64, that alter the three HRD amino acids, were identified.

  10. Src64B overexpression induced the formation of specialized haemocytes (lamellocytes), but had no effect on circulating plasmatocyte concentration. Src64B overexpression induced F-actin (show ACTB Antibodies) formation and Jun kinase (show MAPK9 Antibodies) activation in plasmatocytes.

NCOA1 Antigen Profile

Antigen Summary

The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with NCOA1

  • nuclear receptor coactivator 1 (NCOA1) antibody
  • nuclear receptor coactivator 1 (ncoa1) antibody
  • steroid receptor RNA activator 1 (sra1) antibody
  • steroid receptor RNA activator 1 (SRA1) antibody
  • steroid receptor RNA activator 1 (LOC100345921) antibody
  • nuclear receptor coactivator 1 (Ncoa1) antibody
  • Src oncogene at 64B (Src64B) antibody
  • v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (src-b) antibody
  • bHLHe42 antibody
  • bHLHe74 antibody
  • c-src antibody
  • C-src1 antibody
  • CG7524 antibody
  • csrc antibody
  • D-src antibody
  • D-Src64B antibody
  • DKFZp459C083 antibody
  • Dmel\CG7524 antibody
  • DmHD-358 antibody
  • Dm SRC1 antibody
  • dsrc antibody
  • Dsrc64 antibody
  • Dsrc64B antibody
  • F-SRC-1 antibody
  • HD-358 antibody
  • KAT13A antibody
  • MGC128615 antibody
  • MRE5 antibody
  • NCOA1 antibody
  • pp60c-src antibody
  • pp60v-src antibody
  • RIP160 antibody
  • si:dkey-5g7.6 antibody
  • si:dkey-34f16.6 antibody
  • SRA1 antibody
  • src antibody
  • src-1 antibody
  • src1 antibody
  • src2 antibody
  • src64 antibody
  • SRC 64B antibody
  • src64b antibody
  • xsrc antibody
  • zgc:86613 antibody

Protein level used designations for NCOA1

nuclear receptor coactivator 1 , DKEY-34F16.7 , SRC1 , steroid receptor RNA activator 1 , Hin-2 protein , PAX3/NCOA1 fusion protein , class E basic helix-loop-helix protein 74 , renal carcinoma antigen NY-REN-52 , steroid receptor coactivator-1 , NCoA-1 , SRC-a/NCoA-1 , mNRC-1 , nuclear receptor coactivator protein 1 , steroid receptor coactivator 1 , SRC-1 , CG7524-PB , CG7524-PC , CG7524-PD , CG7524-PE , CG7524-PF , CG7524-PG , CG7524-PH , CG7524-PI , CG7524-PJ , Src proto oncogene sequence , Src64B-PB , Src64B-PC , Src64B-PD , Src64B-PE , Src64B-PF , Src64B-PG , Src64B-PH , Src64B-PI , Src64B-PJ , mRNA-like ncRNA in embryogenesis 5 , p60-Src-2 , tyrosine protein kinase pp60-c-src , tyrosine-protein kinase Src-2 , v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog

422016 Gallus gallus
563288 Danio rerio
459068 Pan troglodytes
100025270 Monodelphis domestica
100385756 Callithrix jacchus
100471908 Ailuropoda melanoleuca
100556605 Anolis carolinensis
415137 Danio rerio
606944 Canis lupus familiaris
780787 Bos taurus
100049723 Xenopus laevis
100135196 Xenopus (Silurana) tropicalis
100173951 Pongo abelii
100345921 Oryctolagus cuniculus
8648 Homo sapiens
17977 Mus musculus
313929 Rattus norvegicus
574068 Sus scrofa
48973 Drosophila melanogaster
380430 Xenopus laevis
475684 Canis lupus familiaris
525346 Bos taurus
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