NCOA1 antibody (AA 1338-1367)

Catalog No. ABIN3032057

The Rabbit Polyclonal anti-NCOA1 antibody is suitable to detect NCOA1 in samples from Human. It has been validated for WB, ELISA and IHC.

Quick Overview for NCOA1 antibody (AA 1338-1367) (ABIN3032057)

Target: NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCOA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-NCOA1 Antibody

Binding Specificity: AA 1338-1367

Purpose: SRC-1 Antibody / NCOA1

Cross-Reactivity (Details): Expected species reactivity: Pig

Purification: Purified

Immunogen: A portion of amino acids 1338-1367 from the human protein was used as the immunogen for this SRC-1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the SRC-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the SRC-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for NCOA1

Target: NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))

Alternative Name: SRC-1

Background: SRC-1/NCOA1 acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. This protein binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion.

UniProt: Q15788

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha