NCOA1 antibody
Quick Overview for NCOA1 antibody (ABIN7269005)
Target
See all NCOA1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- KAT13A / SRC1 Rabbit mAb
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Cross-Reactivity
- Human
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Characteristics
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- A synthesized peptide derived from human KAT13A / SRC1
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000,IP,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))
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Alternative Name
- NCOA1
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Background
- The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],F-SRC-1, KAT13A, RIP160, SRC1, bHLHe42, bHLHe74,Cancer,Endocrine & Metabolism,Epigenetic writers and erasers of core Histones,Epigenetic writers and erasers of core Histones_Acetylation,Epigenetics & Nuclear Signaling,Lipid Metabolism,Nuclear Receptor Signaling,Nuclear Receptor Signaling_Nuclear hormone receptors,Signal Transduction,NCOA1
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Molecular Weight
- 157kDa
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Gene ID
- 8648
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UniProt
- Q15788
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
Target
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