Browse our anti-CISH (CISH) Antibodies

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anti-Cytokine Inducible SH2-Containing Protein Antibodies (CISH)
On are 31 Cytokine Inducible SH2-Containing Protein (CISH) Antibodies from 11 different suppliers available. Additionally we are shipping CISH Proteins (10) and many more products for this protein. A total of 45 CISH products are currently listed.
AI385595, BACTS2, Cis, CIS-1, CIS1, cish, cish.a, F17, F23, G18, ptk9l, SOCS, twf1l, wu:fk57g04, zgc:91817, zgc:154062
list all antibodies Gene Name GeneID UniProt
CISH 1154 Q9NSE2
CISH 12700 Q62225
CISH 83681  

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More Antibodies against CISH Interaction Partners

Zebrafish Cytokine Inducible SH2-Containing Protein (CISH) interaction partners

  1. This study indicates that CISH functions as a conserved in vivo target and regulator of STAT5 (show STAT5B Antibodies) in the control of embryonic hematopoiesis.

Rainbow Trout (Oncorhynchus mykiss) Cytokine Inducible SH2-Containing Protein (CISH) interaction partners

  1. the type II SOCS genes (CISH, SOCS1 (show SOCS1 Antibodies)-3) are particularly relevant to immune regulation in fish

Human Cytokine Inducible SH2-Containing Protein (CISH) interaction partners

  1. Studies indicate that suppressors of cytokine signaling (SOCS) proteins CIS, SOCS1 (show SOCS1 Antibodies), and SOCS3 (show SOCS3 Antibodies) can be considered the third immunocheckpoint molecules since they regulate cytokine signals that control the polarization of CD4 (show CD4 Antibodies)(+) T cells and the maturation of CD8 (show CD8A Antibodies)(+) T cells.

  2. CISH rs414171 and rs6768300 variants might be associated with protection from pulmonary tuberculosis in Zahedan, Southeast Iran.

  3. This study showed that there was significantly increased levels of CIS mRNA in elderly and Alzheimer's disease brains.

  4. Data indicate that CIS protein stability is regulated through multiple mechanisms, including ubiquitination and interaction with Elongin B (show TCEB2 Antibodies)/C proteins, whereas CIS functional inhibition of PRLR (show PRLR Antibodies) signaling is dependent on the Elongin B (show TCEB2 Antibodies)/C interaction.

  5. SOCS single nucleotide polymorphism is associated with breast cancer.

  6. Study in Chinese Han population confirms that previously identified variants of CISH are associated with susceptibility to pulmonary tuberculosis.

  7. CISH gene polymorphisms at -292 (rs414171) are associated with HBV clearance in HBeAg-positive CHB patients in the immune active phase, and AA is a favorable genotype for this effect.

  8. Two SNPs (rs414171 and rs2239751) in the CISH gene were associated with persistent HBV infection in Han Chinese population

  9. two genetic variants in CISH gene appear to increase susceptibility to TB in Chinese Han population

  10. CISH promoter rs414171 and rs809451 polymorphisms may play a vital role in mediating individual susceptibility to tuberculosis

Mouse (Murine) Cytokine Inducible SH2-Containing Protein (CISH) interaction partners

  1. this study identifies CIS as a critical negative regulator of IL-15 (show IL15 Antibodies) signaling in NK cells

  2. Data show that cytokine inducible SH2-containing protein Cish is induced upon T cell receptor stimulation and in the tumor microenvironment.

  3. Results show that CISH has no non-redundant functions in beta cell proliferation or glucose homeostasis during pregnancy in mice. Socs2 (show SOCS2 Antibodies) might compensate for the loss of Cish during pregnancy.

  4. CIS has a critical role in controlling the proallergic generation of helper T cells.

  5. CISH expression at the later stage of dendritic cell development triggers the shutdown of DC progenitor cell proliferation and facilitates DC differentiation into a potent stimulator of CTLs.

  6. CIS and SOCS3 (show SOCS3 Antibodies) play a role as negative feedback inhibitors of PRL (show PRL Antibodies) action; Inhibition of CIS and SOCS3 (show SOCS3 Antibodies) expression by glucocorticoids contributes to the positive effect of glucocorticoids on PRL (show PRL Antibodies)-induced STAT5 (show STAT5A Antibodies) activation.

  7. Induction of CIS in response to EPO (show EPO Antibodies) stimulation depends on Stat5 (show STAT5A Antibodies) but not MAP kinase (show MAPK1 Antibodies) or PI 3 (show PI3 Antibodies)-kinase. Overexpression negatively regulates EPO (show EPO Antibodies)-mediated cell proliferation, Stat5 (show STAT5A Antibodies) phosphorylation, & activation of a Stat (show STAT1 Antibodies)-dependent luciferase reporter.

  8. CIS negatively regulates signaling at two levels, apoptosis and proliferation, and thereby sets a threshold for signal transduction

  9. IL-6 (show IL6 Antibodies) inhibits hepatic GH signaling by upregulating Cis and Socs-3 (show SOCS3 Antibodies), which may involve activation of STAT3 (show STAT3 Antibodies).

  10. histone acetylation and chromatin remodeling events occurring during transcriptional activation of the endogenous murine Cis gene, a STAT5 (show STAT5A Antibodies) target gene

CISH Antigen Profile

Antigen Summary

The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with CISH

  • cytokine inducible SH2-containing protein (CISH) antibody
  • cytokine inducible SH2-containing protein (cish) antibody
  • cytokine-inducible SH2-containing protein (cish) antibody
  • Cytokine-inducible SH2-containing protein (cish) antibody
  • cytokine inducible SH2-containing protein (Cish) antibody
  • AI385595 antibody
  • BACTS2 antibody
  • Cis antibody
  • CIS-1 antibody
  • CIS1 antibody
  • cish antibody
  • cish.a antibody
  • F17 antibody
  • F23 antibody
  • G18 antibody
  • ptk9l antibody
  • SOCS antibody
  • twf1l antibody
  • wu:fk57g04 antibody
  • zgc:91817 antibody
  • zgc:154062 antibody

Protein level used designations for CISH

cytokine inducible SH2-containing protein , cytokine-inducible SH2-containing protein , cytokine inducible SH2 containing protein , cytokine inducible SH2-containing protein A , twinfilin, actin-binding protein, homolog 1, like , Cytokine-inducible SH2-containing protein , cytokine-inducible inhibitor of signaling type 1B , suppressor of cytokine signaling , CIS-1 , SOCS , cytokine-inducible SH2 protein , cytokine inducible SH2-containing protein 1 , CIS

470819 Pan troglodytes
484757 Canis lupus familiaris
701456 Macaca mulatta
767678 Danio rerio
100135018 Xenopus (Silurana) tropicalis
100144307 Takifugu rubripes
100144373 Oryzias latipes
100190868 Gasterosteus aculeatus
100196184 Salmo salar
100329195 Oncorhynchus mykiss
1154 Homo sapiens
12700 Mus musculus
83681 Rattus norvegicus
616753 Bos taurus
395335 Gallus gallus
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