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Browse our IL15RA Proteins (IL15RA)

Full name:
Interleukin 15 Receptor, alpha Proteins (IL15RA)
On are 5 Interleukin 15 Receptor, alpha (IL15RA) Proteins from 2 different suppliers available. Additionally we are shipping IL15RA Antibodies (77) and IL15RA Kits (9) and many more products for this protein. A total of 96 IL15RA products are currently listed.
AA690181, CD215, IL-15RA, IL15RA
list all proteins Gene Name GeneID UniProt
IL15RA 3601 Q13261
Rat IL15RA IL15RA 690369  
IL15RA 16169 Q60819

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IL15RA Proteins (IL15RA) by Origin

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Human Interleukin 15 Receptor, alpha (IL15RA) interaction partners

  1. significant association of rs2228059 with ossification of the posterior longitudinal ligament of the spine in Chinese Han population

  2. NK cell activation in human hantavirus infection explained by virus-induced IL-15 (show IL15 Proteins)/IL15Ralpha expression

  3. IRF-1 (show IRF1 Proteins) promotes LTx I/R injury via hepatocyte IL-15 (show IL15 Proteins)/IL-15Ralpha production and suggest that targeting IRF-1 (show IRF1 Proteins) and IL-15 (show IL15 Proteins)/IL-15Ralpha may be effective in reducing I/R injury associated with LTx.

  4. Coexpression of IL15RA and IL15 (show IL15 Proteins) was also sufficient to activate peripheral blood mononuclear cells.

  5. Circulating levels of IL-15 (show IL15 Proteins) and IL-15Ralpha seem to reflect visceral distribution of adipose tissue; epicardial fat may be a potential source of both IL-15 (show IL15 Proteins) and IL-15Ralpha.

  6. our study provides strong evidence that the functional IL-15RA rs2228059 A>C polymorphism may contribute to the risk of ESCC.

  7. We show that a gene transfer approach using recombinant adenovirus to express IL-15 (show IL15 Proteins) and IL-15Ralpha in murine TRAMP (show DPT Proteins)-C2 prostate or TS/A breast tumors induced antitumor immune responses

  8. This present study demonstrated that IL15RA rs2228059 A > C polymorphism might modify Gastric cardiac adenocarcinoma susceptibility

  9. Data suggest that the Interleukin (IL)-15 (show IL15 Proteins) and interleukin 15 receptor alpha (IL-15 (show IL15 Proteins).IL-15Ralpha) complex cleaved from presenting cells allows responding cells to internalize, store and use IL-15 (show IL15 Proteins).IL-15Ralpha complex for their own proliferation and survival.

  10. Data indicate that tumor necrosis factor-alpha (TNF (show TNF Proteins)) abolishes nuclear localization of IL-15 (show IL15 Proteins) and IL-15Ralpha by acting on chromosomal region maintenance 1 (CRM1), and it facilitates exocytosis of IL-15 (show IL15 Proteins) with the involvement of ADP-ribosylation factor 6 (ARF6 (show ARF6 Proteins)).

Mouse (Murine) Interleukin 15 Receptor, alpha (IL15RA) interaction partners

  1. Spontaneous cage activity was not different and IL-15 (show IL15 Proteins) protein levels were lower in male and female mIl15ra(fl/fl (show FLT3LG Proteins))/Cre(+) mice.

  2. Despite being protected against diet induced obesity, IL-15R alpha knockout mice are hyperglycemic and insulin (show INS Proteins)-resistant.

  3. IL-15 (show IL15 Proteins) directly induces pro-oxidative gene expression in primary myogenic cultures. Primary myogenic cultures require IL-15RA to respond to IL-15 (show IL15 Proteins).

  4. we found that aging-related functional NK cell deficiency was completely reversed by injecting soluble IL-15 (show IL15 Proteins)/IL-15Ralpha complexes.

  5. a greater mitochondrial density and mitochondrial DNA content was found in fast muscles from IL-15-Receptor-alpha KO mice that was not due to the presence of smaller muscle fibers.

  6. IL-15 (show IL15 Proteins) is produced and secreted only as a heterodimer with IL-15Ralpha.

  7. IL-15 (show IL15 Proteins) can signal via IL-15Ralpha, JNK (show MAPK8 Proteins), and NF-kappaB (show NFKB1 Proteins) to drive RANTES (show CCL5 Proteins) production by myeloid cells.

  8. Stage 3 thymic invariant natural killer NKT (show CTSL1 Proteins) cells are specifically reduced in IL-15Ralpha-deficient mice, whereas the acquisition of natural killer (NK) receptors occurs at stage 3 IL15 (show IL15 Proteins)-dependent thymic cell development.

  9. Different levels of IL-15 (show IL15 Proteins) trans-presentation are required for different natural killer (NK) cell developmental events to reach full maturation status

  10. IL-15 receptor alpha has a role in endurance, fatigability, and metabolic characteristics of mouse fast skeletal muscles

IL15RA Protein Profile

Protein Summary

This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.

Alternative names and synonyms associated with IL15RA

  • interleukin 15 receptor, alpha (IL15RA)
  • interleukin 15 receptor, alpha (Il15ra)
  • interleukin 15 receptor, alpha chain (Il15ra)
  • AA690181 protein
  • CD215 protein
  • IL-15RA protein
  • IL15RA protein

Protein level used designations for IL15RA

interleukin-15 receptor subunit alpha , interleukin 15 receptor alpha , interleukin 15 receptor, alpha , interleukin 15 receptor, alpha chain , IL-15 receptor subunit alpha , IL-15R-alpha

712788 Macaca mulatta
733692 Sus scrofa
738192 Pan troglodytes
3601 Homo sapiens
690369 Rattus norvegicus
487141 Canis lupus familiaris
615030 Bos taurus
16169 Mus musculus
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