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IL15RA Protein (AA 31-205) (Fc Tag)

IL15RA Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Catalog No. ABIN6809889
  • Target See all IL15RA Proteins
    IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 31-205
    Origin
    • 16
    • 6
    • 1
    Human
    Source
    • 10
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IL15RA protein is labelled with Fc Tag.
    Sequence
    AA 31-205
    Purity
    >95 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IL15RA Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
  • Target
    IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
    Alternative Name
    IL-15 R alpha (IL15RA Products)
    Synonyms
    IL15RA Protein, CD215 Protein, AA690181 Protein, IL-15RA Protein, interleukin 15 receptor subunit alpha Protein, interleukin 15 receptor, alpha chain Protein, IL15RA Protein, Il15ra Protein
    Background
    IL15R is a heterotrimer of IL15RA, IL2RB and IL2RG. IL-15RA, also known as CD215, IL-15 R alpha, is a widely expressed 60 kDa transmembrane glycoprotein. High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Expression of different isoforms may alter or interfere with signal transduction. An interleukin (IL)-15 superagonist/IL-15 receptor α fusion complex (IL-15SA/IL-15RA, ALT-803) activates the IL-15 receptor on CD8 T cells and NK cells, and has shown significant anti-tumor. Signal transduction involves SYK. Higher levels of soluble sIL-15RA form in comparison with membrane-bound forms is present in all brain structures.
    Molecular Weight
    44.8 kDa
    NCBI Accession
    NP_002180
    Pathways
    JAK-STAT Signaling
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