IL15RA Protein (Fc Tag)
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- Target See all IL15RA Proteins
- IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Mouse
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Source
- Human Cells
- Purification tag / Conjugate
- This IL15RA protein is labelled with Fc Tag.
- Purpose
- Recombinant Mouse IL15RA/CD215 Protein (Fc Tag)(Active)
- Sequence
- Gly33-Lys205
- Characteristics
- Recombinant Mouse Interleukin-15 receptor subunit alpha is produced by our Mammalian expression system and the target gene encoding Gly33-Lys205 is expressed with a Fc tag at the C-terminus.
- Purity
- > 90 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Measured by its ability to block human IL-15-induced proliferation of CTLL-2 mouse cytotoxic T cells. The ED50 for this effect is 0.5-2 ng/ml.
- Top Product
- Discover our top product IL15RA Protein
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Interleukin 15 Receptor, alpha (IL15RA) protein (Fc Tag)
IL15RA Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Interleukin 15 Receptor, alpha (IL15RA) protein (His-Avi Tag)IL15RA Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Interleukin 15 Receptor, alpha (IL15RA) protein (His-Avi Tag,Biotin)IL15RA Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Interleukin 15 Receptor, alpha (IL15RA) (AA 33-205) protein (Fc Tag)IL15RA Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 15 Receptor, alpha (IL15RA) (AA 31-205) (Active) protein (Fc Tag,AVI tag,Biotin)IL15RA Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Interleukin 15 Receptor, alpha (IL15RA) (AA 31-130) protein (GST tag)IL15RA Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 15 Receptor, alpha (IL15RA) (AA 31-205) protein (His tag)Crystallography grade IL15RA Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 15 Receptor, alpha (IL15RA) (AA 33-205) protein (His tag)Crystallography grade IL15RA Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 15 Receptor, alpha (IL15RA) (AA 31-267) protein (rho-1D4 tag)Crystallography grade IL15RA Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 15 Receptor, alpha (IL15RA) (AA 33-263) protein (rho-1D4 tag)Crystallography grade IL15RA Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
- Alternative Name
- IL15RA/CD215 (IL15RA Products)
- Synonyms
- IL15RA Protein, CD215 Protein, AA690181 Protein, IL-15RA Protein, interleukin 15 receptor subunit alpha Protein, interleukin 15 receptor, alpha chain Protein, IL15RA Protein, Il15ra Protein
- Background
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Background: Mouse interleukin-15 receptor subunit alpha, also known as Il15ra, is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits (Common gamma chain, or gamma c) to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells. Human Il15ra shares 45 % amino acid sequence homology with the mouse form of the receptor. Eight isoforms of IL-15 R alpha mRNA have been identified, resulting from alternative splicing events involving different exons.
Synonym: Interleukin-15 receptor subunit alpha,Il15ra,sIL-15 receptor subunit alpha
- Molecular Weight
- 45.5 kDa
- UniProt
- Q60819
- Pathways
- JAK-STAT Signaling
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