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IL15RA Protein (Fc Tag,His tag)

IL15RA Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % by SDS-PAGE. Active
Catalog No. ABIN7535325
  • Target See all IL15RA Proteins
    IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 16
    • 5
    • 1
    Mouse
    Source
    • 10
    • 4
    • 3
    • 3
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IL15RA protein is labelled with Fc Tag,His tag.
    Purpose
    Active Recombinant Mouse IL-15RA/CD215 Protein
    Sequence
    GTTCPPPVSI EHADIRVKNY SVNSRERYVC NSGFKRKAGT STLIECVINK NTNVAHWTTP SLKCIRDPSL AHYSPVPTVV TPKVTSQPES PSPSAKEPEA FSPKSDTAMT TETAIMPGSR LTPSQTTSAG TTGTGSHKSS RAPSLAATMT LEPTASTSLR ITEISPHSSK MTK
    Specificity
    Gly33-Lys205
    Purity
    > 95 % by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    <0.1EU/μg
    Biological Activity Comment
    Measured by its binding ability in a functional ELISA.Immobilized Human IL15 at 1 μg/mL (100 μL/well) can bind Mouse IL15RA with a linear range of 0.3-77 ng/mL.
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    Discover our top product IL15RA Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    Buffer
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
  • Target
    IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
    Alternative Name
    IL-15RA/CD215 (IL15RA Products)
    Synonyms
    IL15RA Protein, CD215 Protein, AA690181 Protein, IL-15RA Protein, interleukin 15 receptor subunit alpha Protein, interleukin 15 receptor, alpha chain Protein, IL15RA Protein, Il15ra Protein
    Background

    Description: Mouse interleukin-15 receptor subunit alpha, also known as Il15ra, is a high-affinity receptor for interleukin-15.Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits (Common gamma chain, orgamma c) to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cellspresents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide varietyof Tand B cells and non-lymphoid cells. Human Il15ra shares 45 % amino acid sequence homology with themouse form of the receptor. Eight isoforms of IL-15 R alpha mRNA have been identified, resulting fromalternative splicing events involving different exons.

    Name: IL-15RA,CD215,AA690181,IL15RA

    Gene ID
    16169
    UniProt
    Q60819-1
    Pathways
    JAK-STAT Signaling
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