Browse our BUB3 Proteins (BUB3)

Full name:
Budding Uninhibited By Benzimidazoles 3 Homolog (Yeast) Proteins (BUB3)
On are 8 Budding Uninhibited By Benzimidazoles 3 Homolog (Yeast) (BUB3) Proteins from 5 different suppliers available. Additionally we are shipping BUB3 Antibodies (99) and many more products for this protein. A total of 113 BUB3 products are currently listed.
Aa2-050, AU019800, AU021329, AU043350, AW146323, BUB3L, C78067, hBUB3, xbub3
list all proteins Gene Name GeneID UniProt
BUB3 9184 O43684
Rat BUB3 BUB3 361662  
BUB3 12237 Q9WVA3

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BUB3 Proteins (BUB3) by Origin

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Top referenced BUB3 Proteins

  1. Human BUB3 Protein expressed in Escherichia coli (E. coli) - ABIN1098754 : Martinez-Exposito, Kaplan, Copeland, Sorger: Retention of the BUB3 checkpoint protein on lagging chromosomes. in Proceedings of the National Academy of Sciences of the United States of America 1999 (PubMed)
    Show all 2 references for 1098754

More Proteins for BUB3 Interaction Partners

Human Budding Uninhibited By Benzimidazoles 3 Homolog (Yeast) (BUB3) interaction partners

  1. The integrity of the mitotic checkpoint complex depends on the specific recognition between BubR1 (show BUB1B Proteins) and Bub3, for which the BubR1 (show BUB1B Proteins) Gle2 (show RAE1 Proteins) binding sequence motif is essential.

  2. We show that kinetochore recruitment of BUBR1 (show BUB1B Proteins) and BUB3 by BUB1 (show BUB1 Proteins) is dispensable for SAC (show ADCY10 Proteins) activation

  3. a mutual antagonism exists between Bub3 and dynein to ensure optimal KT-MT attachments

  4. the mechanisms of BUB3 in mitotic checkpoint signaling

  5. Data show sequential multisite regulation of the microtubule-associated protein KNL1-kinase-adaptor complex BUB1 (show BUB1 Proteins)/BUB3 interaction.

  6. Data indicate that cell cycle protein Bub3-mediated kinetochore recruitment of BubR1 (show BUB1B Proteins) kinase enhances mitotic checkpoint signaling.

  7. Results suggest that these USP7 (show USP7 Proteins)-dependent effects are mediated by decreased levels of spindle assembly checkpoint (SAC (show ADCY10 Proteins)) component Bub3.

  8. Mutations targeting the Bub3 interface prevent kinetochore recruitment of the SAC (show ADCY10 Proteins) kinase Bub1 (show BUB1 Proteins). Crucially, they also cause a checkpoint defect, showing that recognition of phosphorylated targets by Bub3 is required for checkpoint signaling

  9. Results showed that neither variants in BUB3 nor variants in MAD2L1 (show MAD2L1 Proteins) caused any significant effect on the risk of breast cancer

  10. Mutations in BUB1 (show BUB1 Proteins) and BUB3 cause mosaic variegated aneuploidy and increase the risk of colorectal cancer at a young age.

Mouse (Murine) Budding Uninhibited By Benzimidazoles 3 Homolog (Yeast) (BUB3) interaction partners

  1. as a member of the spindle assembly checkpoint, Bub3 is required for regulation of both meiosis I and II, and is potentially involved in kinetochore-microtubule attachment in mammalian oocytes

  2. Cenpa (show CENPA Proteins), Cenpb (show CENPB Proteins), and Bub3, but not Cenpc, interacted with PARP-1 (show PARP1 Proteins)

  3. Haploinsufficiency of Bub3 causes a slight increase in chromosome instability but is not clearly associated with a noticeable rise in the probability of tumor formation.

  4. subpopulation of dynein, containing the DYNLT3 (show DYNLT3 Proteins) light chain, may be important for chromosome congression, in addition to having a role in the transport of checkpoint proteins from the kinetochore to the spindle pole

BUB3 Protein Profile

Protein Summary

This gene encodes a protein involved in spindle checkpoint function. The encoded protein contains four WD repeat domains and has sequence similarity with the yeast BUB3 protein. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alternative names and synonyms associated with BUB3

  • BUB3 mitotic checkpoint protein (BUB3)
  • BUB3 mitotic checkpoint protein (Bub3)
  • BUB3 mitotic checkpoint protein (bub3)
  • budding uninhibited by benzimidazoles 3 homolog (S. cerevisiae) (Bub3)
  • budding uninhibited by benzimidazoles 3 homolog (yeast) (BUB3)
  • Aa2-050 protein
  • AU019800 protein
  • AU021329 protein
  • AU043350 protein
  • AW146323 protein
  • BUB3L protein
  • C78067 protein
  • hBUB3 protein
  • xbub3 protein

Protein level used designations for BUB3

BUB3 budding uninhibited by benzimidazoles 3 homolog , budding uninhibited by benomyl , budding uninhibited by benzimidazoles 3 homolog , mitotic checkpoint component , mitotic checkpoint protein BUB3 , WD repeat protein Bub3 , WD repeat type I transmembrane protein A72.5

9184 Homo sapiens
361662 Rattus norvegicus
399106 Xenopus laevis
12237 Mus musculus
423949 Gallus gallus
539594 Bos taurus
477857 Canis lupus familiaris
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