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Browse our anti-CDC42 (CDC42) Antibodies

Full name:
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) Antibodies (CDC42)
On are 106 Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) Antibodies from 26 different suppliers available. Additionally we are shipping CDC42 Proteins (23) and CDC42 Kits (11) and many more products for this protein. A total of 157 CDC42 products are currently listed.
AI747189, AU018915, Cdc42, cdc42a, Cdc42Dm, CDC42Hs, CG12530, D-cdc42, Dcdc42, Dm Cdc42, Dmcdc42, Dmel\\CG12530, G25K, wu:fb07d08, wu:fi33d02, wu:fj62g06, Xcdc42, zgc:55427, zgc:63918, zgc:86687
list all antibodies Gene Name GeneID UniProt
CDC42 998 P60953
CDC42 12540 P60766
CDC42 64465 Q8CFN2

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Most Popular Reactivities for anti-CDC42 (CDC42) Antibodies

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anti-Human CDC42 Antibodies:

anti-Mouse (Murine) CDC42 Antibodies:

anti-Rat (Rattus) CDC42 Antibodies:

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Top referenced anti-CDC42 Antibodies

  1. Dog (Canine) Monoclonal CDC42 Primary Antibody for IF, WB - ABIN968255 : Brandt, Gimona, Hillmann, Haller, Mischak: Protein kinase C induces actin reorganization via a Src- and Rho-dependent pathway. in The Journal of biological chemistry 2002 (PubMed)
    Show all 5 references for ABIN968255

  2. Human Polyclonal CDC42 Primary Antibody for EIA, WB - ABIN783578 : Chen, Lim, Lim: The CDC42 homologue from Caenorhabditis elegans. Complementation of yeast mutation. in The Journal of biological chemistry 1993 (PubMed)
    Show all 2 references for ABIN783578

  3. Dog (Canine) Polyclonal CDC42 Primary Antibody for IHC, WB - ABIN2792111 : Black, Trackman et al.: Transforming growth factor-beta1 (TGFbeta1) stimulates connective tissue growth factor (CCN2/CTGF) expression in human gingival fibroblasts through a RhoA-independent, Rac1/Cdc42-dependent mechanism: ... in The Journal of biological chemistry 2008 (PubMed)

  4. Human Polyclonal CDC42 Primary Antibody for FACS, WB - ABIN390921 : Landry, Sicotte, Champagne, Lavoie: Regulation of cell death by recycling endosomes and golgi membrane dynamics via a pathway involving Src-family kinases, Cdc42 and Rab11a. in Molecular biology of the cell 2009 (PubMed)

More Antibodies against CDC42 Interaction Partners

Zebrafish Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) interaction partners

  1. Knockdown of fat1 (show FAT1 Antibodies) in zebrafish causes pronephric cysts, which is partially rescued by RAC1/CDC42 activators, confirming a role of the two small GTPases in the pathogenesis.

  2. Cdc42 deficiency causes ciliary abnormalities and cystic kidneys.

  3. Cdc42 GTPase (show RACGAP1 Antibodies) and Rac1 GTPase (show RACGAP1 Antibodies) act downstream of p120 catenin (show CTNND1 Antibodies) and require GTP (show AK3 Antibodies) exchange during gastrulation of zebrafish mesoderm.

  4. These results suggest that Ptenb by antagonizing PI3 kinase and its downstream Akt1 and Cdc42 to regulate actin polymerization that is critical for proper cell motility and migration control during gastrulation in zebrafish.

Xenopus laevis Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) interaction partners

  1. This suggests that TOCA1 binding to Cdc42 is an early step in the Cdc42-dependent pathways that govern actin dynamics, and the differential binding affinities of the effectors facilitate a handover from TOCA1 to N-WASP, which can then drive recruitment of the actin-modifying machinery.

  2. The small GTPase Cdc42 promotes membrane protrusion during polar body emission via ARP2-nucleated actin polymerization.

  3. these data indicate that the ITSN2 exchange factor regulates the activity of Cdc42 during embryo development affecting actin cytoskeleton in Xenopus embryos.

  4. These results demonstrate that to participate in the control of the actin cytoskeleton, RLIP needs its complete N-terminal region coding for the mu2BD and the GAP domain.

  5. Data show that in Xenopus laevis oocytes, polar body emission requires a RhoA (show RHOA Antibodies) contractile ring and Cdc42-mediated membrane protrusion.

  6. In vivo imaging reveals a role for Cdc42 in spindle positioning and planar orientation of cell divisions during vertebrate neural tube closure.

Fruit Fly (Drosophila melanogaster) Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) interaction partners

  1. Cdc42 controls protrusion formation in a cell non-autonomous manner.

  2. Cdc42 regulates binding of Crumbs protein to the Par-6 (show PARD6A Antibodies) CRIB (show SCRIB Antibodies)-PDZ (show INADL Antibodies) module.

  3. We propose that the guanine nucleotide exchange factor GEFmeso is involved in a developmental process that requires the synergistic action of CDC42 and Rac1 during Drosophila development

  4. A proof-of-principle experiment in which the Cdc42 GTPase (show RACGAP1 Antibodies) associates with its alleged partner WASp (show WASL Antibodies) within neurons during the time and space that coincide with the newly developing CNS.

  5. The distinct buttoning mechanism we propose for dorsal vessel closure is elaborated through signaling pathways regulating Cdc42 activity in this cell type.

  6. there is a mutual dependence between Par proteins and Cdc42 for their localization, regulation of the actin cytoskeleton and, consequently, for the establishment of oocyte polarity

  7. Zir is necessary to activate the Rho-family GTPases Rac2 (show RAC2 Antibodies) and Cdc42 during the Drosophila cellular immune response.

  8. Results identify the Cdc42/Par6 (show PARD6A Antibodies)/atypical protein kinase C (show PRKCZ Antibodies) (aPKC) Par (show AFG3L2 Antibodies) polarity complex as uniquely and specifically regulating apoptosis-induced compensatory proliferation in Drosophila epithelia.

  9. Wsp activity in within the fly testis is mediated by the small GTPase (show RACGAP1 Antibodies) Cdc42.

  10. Data demonstrate that Cdc42 and Merlin (show NF2 Antibodies) act together with Pak1 (show PAK1 Antibodies) to control salivary gland lumen size.

Pig (Porcine) Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) interaction partners

  1. Hypoxic pulmonary arterial myocytes challenged with a thromboxane mimetic polymerize actin via the Cdc42 pathway, reflecting increased Cdc42 association with neuronal Wiskott Aldrich Syndrome protein.

  2. Cdc42 is involved in the regulation of alppha-smooth muscle actin promoter activation through p21 (show CDKN1A Antibodies)-activated kinase, p38 (show MAPK14 Antibodies), myocardin (show MYOCD Antibodies)-related transcription factor and serum response factor. Cdc42 may be an important regulator of MRTF cellular localization

Human Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) interaction partners

  1. rapamycin inhibits the RhoA (show RHOA Antibodies), Rac1, and Cdc42 activated by high glucose(HG). Thus, rapamycin shows an obvious protective effect on HG-induced Epithelial-mesenchymal transition, by inhibiting the activation of Rho GTPases (RhoA (show RHOA Antibodies), Rac1, and Cdc42).

  2. Akt3 (show AKT3 Antibodies) constitutively suppresses macropinocytosis in macrophages through a novel WNK1 (show WNK1 Antibodies)/SGK1 (show SGK1 Antibodies)/Cdc42 pathway.

  3. These data were confirmed by phosphomimetic mutation of serine 1443 to glutamate within RGCT, which led to a significant reduction of IQGAP1 affinity for CDC42 and RAC1, clearly disclosing the critical role of RGCT for these interactions.

  4. Report shows Cdc42 as a downstream target of miR (show MLXIP Antibodies)-107.

  5. endocytosis vesicle enrichment of GRP75 (show HSPA9 Antibodies) by mitochondria trafficking upregulates clathrin-independent endocytosis through an actin cytoskeleton reorganization mechanism mediated by the concurrent activation of Cdc42 and RhoA (show RHOA Antibodies).

  6. Results show that cdc42 is a direct target of miR (show MLXIP Antibodies)-186 through its 3'UTR (show UTS2R Antibodies) down-regulating cdc42 protein level in a post-transcriptional manner.

  7. Epistasis analysis identified a statistically significant interaction between CDC42 and SCIN SNPs which are strongly associated with CDC42 and SCIN gene expression levels and map to regulatory elements in skin cells. This interaction has important biological relevance since CDC42 and SCIN proteins have opposite effects in actin cytoskeleton organization and dynamics, which underlies melanoma cell migration and invasion.

  8. Here we briefly overview how mutations in Cdc42-specific GEFs have an impact on the organization of intracellular trafficking fluxes and how such trafficking aberrations could be associated with a number of human disorders.

  9. High p21-activated kinase 1 (show PAK1 Antibodies) and cell division control protein 42 homolog expressions are closely related to the clinicopathological features and poor prognosis of cervical carcinoma, serving as unfavorable prognostic factors.

  10. High expression of CDC42 is associated with glioma.

Mouse (Murine) Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) interaction partners

  1. These results indicate that HuR (show ELAVL1 Antibodies) promotes early intestinal mucosal repair after injury by increasing Cdc42 translation.

  2. Lrrk1 deficiency in osteoclasts resulted in reduced phosphorylation and activation of RAC1/Cdc42

  3. Akt3 (show AKT3 Antibodies) constitutively suppresses macropinocytosis in macrophages through a novel WNK1 (show WNK1 Antibodies)/SGK1 (show SGK1 Antibodies)/Cdc42 pathway.

  4. Cdc42 is essential for cardiomyocyte proliferation, sarcomere organization and cell-cell adhesion during heart development.

  5. presentation of a form of biochemical computation in dendrites involving the controlled complementation of three molecules--Rac1, RhoA (show RHOA Antibodies) and Cdc42--that simultaneously ensures signal specificity and primes the system for BDNF (show BDNF Antibodies)-dependent homo- and heterosynaptic plasticity

  6. Cdc42 is involved not in osteogenesis but in chondrogenesis in which the BMP2 (show BMP2 Antibodies)/Cdc42/Pak/p38 (show CRK Antibodies)/Smad (show SMAD1 Antibodies) signaling module promotes mesenchymal condensation and the TGF-beta (show TGFB1 Antibodies)/Cdc42/Pak/Akt (show AKT1 Antibodies)/Sox9 (show SOX9 Antibodies) signaling module facilitates chondrogenic differentiation.

  7. These data show that membrane protrusions originate from surface ectodermal cells and that Rac1 is necessary for the formation of membrane ruffles which typify late neural fold closure stages, whereas Cdc42 is required for the predominance of filopodia in early neurulation.

  8. findings demonstrate that Cdc42 plays essential roles in mammary gland function post pregnancy, where it helps to establish proper epithelial cell polarity and tissue homeostasis during lactation.

  9. This work demonstrated miR (show MLXIP Antibodies)-137 and CDC42 are critical regulators in cardiomyocyte apoptosis.

  10. the principal role of Cdc42 in ureteric bud and metanephric mesenchyme development is to regulate epithelial cell polarity and the actin cytoskeleton.

Cow (Bovine) Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) interaction partners

  1. shear-stimulated integrin dynamics induce polarized Cdc42 activity, which induces MTOC localization through the Par6-protein kinase Czeta complex.

  2. This study revealed a novel signaling pathway activated during M. avium subsp. paratuberculosis entry that links the product of MAP3464 gene to activation of Cdc42 in the host cell.

  3. These data are consistent with the idea that migrating corneal epithelial cells use a cdc42/rho "switch" to sort vectoral cues, with cdc42 controlling electrotaxis and rho controlling contact guidance.

Candida albicans Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) interaction partners

  1. genetic interactions with CDC42-related genes MSB1, a putative scaffold protein, and RGD3, a putative Rho GTPase-activating protein (GAP) were identified

  2. Rsr1 focuses Cdc42 activity at hyphal tips and promotes maintenance of hyphal development in Candida albicans.

  3. These results suggest the development of hyphal-specific characteristics is promoted by Cdc42-GTP (show AK3 Antibodies) in a process that also requires the intrinsic GTPase (show RACGAP1 Antibodies) activity of Cdc42.

CDC42 Antigen Profile

Antigen Summary

The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20.

Alternative names and synonyms associated with CDC42

  • cell division cycle 42 (cdc42) antibody
  • CG12530 gene product from transcript CG12530-RC (Cdc42) antibody
  • cell division cycle 42 (CDC42) antibody
  • cell division cycle 42, like (cdc42l) antibody
  • Cell division control protein 42 homolog (CDC42) antibody
  • cell division control protein 42 homolog (LOC100386331) antibody
  • cell division control protein 42 homolog (LOC100392513) antibody
  • cell division control protein 42 homolog (LOC100404291) antibody
  • cell division control protein 42 homolog (LOC100424807) antibody
  • cell division cycle 42 (GTP binding protein, 25kDa) (CDC42) antibody
  • cell division control protein 42 homolog (LOC100455652) antibody
  • cell division control protein 42 homolog (LOC100465076) antibody
  • cell division control protein 42 homolog (LOC100627190) antibody
  • cell division control protein 42 homolog (LOC100636735) antibody
  • cell division control protein 42 homolog (LOC100637699) antibody
  • cell division control protein 42 homolog (LOC100638834) antibody
  • cell division cycle 42 (GTP binding protein, 25kDa) (TGas120g11.1) antibody
  • cell division cycle 42 (Cdc42) antibody
  • cell division cycle 42 (GTP binding protein) (Cdc42) antibody
  • one of two genes similar to S. cerevisiae CDC42 (YLR229C) rho family small monomeric GTPase; signal transduction (CDC42) antibody
  • AI747189 antibody
  • AU018915 antibody
  • Cdc42 antibody
  • cdc42a antibody
  • Cdc42Dm antibody
  • CDC42Hs antibody
  • CG12530 antibody
  • D-cdc42 antibody
  • Dcdc42 antibody
  • Dm Cdc42 antibody
  • Dmcdc42 antibody
  • Dmel\\CG12530 antibody
  • G25K antibody
  • wu:fb07d08 antibody
  • wu:fi33d02 antibody
  • wu:fj62g06 antibody
  • Xcdc42 antibody
  • zgc:55427 antibody
  • zgc:63918 antibody
  • zgc:86687 antibody

Protein level used designations for CDC42

Cdc42 protein homolog , cell division control protein 42 homolog , fj62g06 , cell division cycle 42 (GTP binding protein, 25kDa) , CG12530-PA , CG12530-PB , CG12530-PC , CG12530-PD , CG12530-PE , CG12530-PF , Cdc42-PA , Cdc42-PB , Cdc42-PC , Cdc42-PD , Cdc42-PE , Cdc42-PF , Cdc42-like , cdc42c , cell division cycle 42 homolog , Cell division control protein 42 homolog , cell division control protein 42-like protein , G25K GTP-binding protein , GTP binding protein, 25kDa , GTP-binding protein, 25kD , dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD)) , dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD)) , growth-regulating protein , small GTP binding protein CDC42 , CDC42 GTP-binding protein , likely rho family Ras-like GTPase

336839 Danio rerio
379055 Xenopus laevis
32981 Drosophila melanogaster
745248 Pan troglodytes
793158 Danio rerio
4836688 Scheffersomyces stipitis CBS 6054
100386331 Callithrix jacchus
100392513 Callithrix jacchus
100404291 Callithrix jacchus
100424807 Macaca mulatta
100438199 Pongo abelii
100455652 Pongo abelii
100465076 Ailuropoda melanoleuca
100528978 Ictalurus punctatus
100627190 Sus scrofa
100636735 Amphimedon queenslandica
100637699 Amphimedon queenslandica
100638834 Amphimedon queenslandica
456609 Pan troglodytes
493389 Xenopus (Silurana) tropicalis
549824 Xenopus (Silurana) tropicalis
607535 Canis lupus familiaris
707637 Macaca mulatta
100227983 Taeniopygia guttata
998 Homo sapiens
12540 Mus musculus
395917 Gallus gallus
403934 Canis lupus familiaris
532712 Bos taurus
780428 Sus scrofa
64465 Rattus norvegicus
3646488 Candida albicans SC5314
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