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CDC42 antibody
CDC42
Reactivity: Human, Mouse, Rat
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CDC42 Antibody
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Target
See all CDC42 Antibodies
CDC42
(Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
Reactivity
All reactivities for CDC42 antibodies
Human, Mouse, Rat
Host
All hosts for CDC42 antibodies
Rabbit
Clonality
All clonalities for CDC42 antibodies
Polyclonal
Conjugate
All conjugates for CDC42 antibodies
This CDC42 antibody is un-conjugated
Application
All applications for CDC42 antibodies
Western Blotting (WB), ELISA
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Synthetic peptide of human CDC42/RHO/RAC
Isotype
IgG
Top Product
Discover our top product CDC42 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB 1:200-1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.3 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for CDC42
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Target
CDC42
(Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
Alternative Name
CDC42 (CDC42 Products )
Synonyms
CDC42Hs antibody, G25K antibody, AI747189 antibody, AU018915 antibody, cdc42a antibody, wu:fb07d08 antibody, wu:fj62g06 antibody, zgc:63918 antibody, Xcdc42 antibody, cdc42hs antibody, g25k antibody, CDC42 antibody, CG12530 antibody, Cdc42Dm antibody, D-CDC42 antibody, D-Cdc42 antibody, D-cdc42 antibody, DCDC42 antibody, DCdc42 antibody, Dcdc42 antibody, Dm Cdc42 antibody, DmCDC42 antibody, Dmcdc42 antibody, Dmel\\CG12530 antibody, cdc42 antibody, cell division cycle 42 antibody, Cell division control protein 42 homolog antibody, cell division control protein 42 homolog antibody, cell division cycle 42 L homeolog antibody, CG12530 gene product from transcript CG12530-RC antibody, Rho family GTPase antibody, CDC42 antibody, Cdc42 antibody, cdc42 antibody, LOC100636735 antibody, LOC100637699 antibody, LOC100638834 antibody, cdc42.L antibody
Background
The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants.
Molecular Weight
23 kDa
NCBI Accession
NP_001782
UniProt
P60953
Pathways
MAPK Signaling , Microtubule Dynamics , RTK Signaling , WNT Signaling , TCR Signaling , EGFR Signaling Pathway , Regulation of Actin Filament Polymerization , Regulation of Muscle Cell Differentiation , Cell-Cell Junction Organization , Maintenance of Protein Location , Skeletal Muscle Fiber Development , Signaling Events mediated by VEGFR1 and VEGFR2 , EGFR Downregulation , VEGF Signaling
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