CDC42 Products
(Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
Categories
The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013].
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Featured CDC42 Categories
CDC42 Antibodies
High quality antibodies with extensive validation data.
CDC42 ELISA Kits
Reliable ELISA kits for a wide range of species.
CDC42 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CDC42 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (2)
- (8)
Cat. No.
ABIN3021671
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, ICC
Validations
- (1)
- (2)
Cat. No.
ABIN533151
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7127414
Quantity
100 μL
Datasheet
Datasheet
Recommended CDC42 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965621
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954549
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6951508
Quantity
96 tests
Datasheet
Datasheet
Recommended CDC42 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348833
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348831
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348827
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our CDC42 products
: "miR-29a regulated ER-positive breast cancer cell growth and invasion and is involved in the insulin signaling pathway." in: Oncotarget, Vol. 8, Issue 20, pp. 32566-32575, (2018) (PubMed).: "Dcf1 Triggers Dendritic Spine Formation and Facilitates Memory Acquisition." in: Molecular neurobiology, Vol. 55, Issue 1, pp. 763-775, (2018) (PubMed).
: "Astrocytic CCAAT/Enhancer-Binding Protein Delta Contributes to Glial Scar Formation and Impairs Functional Recovery After Spinal Cord Injury." in: Molecular neurobiology, Vol. 53, Issue 9, pp. 5912-5927, (2018) (PubMed).
: "Novel derivative of Paeonol, Paeononlsilatie sodium, alleviates behavioral damage and hippocampal dendritic injury in Alzheimer's disease concurrent with cofilin1/phosphorylated-cofilin1 and ..." in: PLoS ONE, Vol. 12, Issue 9, pp. e0185102, (2017) (PubMed).
: "Overexpression cdc42 attenuates isoflurane-induced neurotoxicity in developmental brain of rats." in: Biochemical and biophysical research communications, Vol. 490, Issue 3, pp. 719-725, (2017) (PubMed).
: "Quantitative proteomics analysis reveals BAG3 as a potential target to suppress severe acute respiratory syndrome coronavirus replication." in: Journal of virology, Vol. 84, Issue 12, pp. 6050-9, (2010) (PubMed).
: "IQGAP1 regulates cell proliferation through a novel CDC42-mTOR pathway." in: Journal of cell science, Vol. 122, Issue Pt 12, pp. 2024-33, (2009) (PubMed).
: "Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation." in: Genes & development, Vol. 17, Issue 2, pp. 295-309, (2003) (PubMed).
: "Protein kinase C induces actin reorganization via a Src- and Rho-dependent pathway." in: The Journal of biological chemistry, Vol. 277, Issue 23, pp. 20903-10, (2002) (PubMed).
: "Raf-MEK-Erk cascade in anoikis is controlled by Rac1 and Cdc42 via Akt." in: Molecular and cellular biology, Vol. 21, Issue 19, pp. 6706-17, (2001) (PubMed).
Synonyms and alternative names related to CDC42
cell division cycle 42 (CDC42), cell division cycle 42 (Cdc42), Cell division control protein 42 homolog (CDC42), cell division cycle 42 (cdc42), cell division control protein 42 homolog (LOC100636735), cell division control protein 42 homolog (LOC100637699), cell division control protein 42 homolog (LOC100638834), cell division cycle 42 L homeolog (cdc42.L), CG12530 gene product from transcript CG12530-RC (Cdc42), Rho family GTPase (CDC42), AI747189, AU018915, CDC42, cdc42, cdc42a, Cdc42Dm, CDC42Hs, cdc42hs, CG12530, D-CDC42, D-Cdc42, D-cdc42, DCDC42, DCdc42, Dcdc42, Dm Cdc42, DmCDC42, Dmcdc42, Dmel\\CG12530, G25K, g25k, wu:fb07d08, wu:fj62g06, Xcdc42, zgc:63918Protein level used designations for CDC42
- G25K GTP-binding protein
- GTP binding protein, 25kDa
- GTP-binding protein, 25kD
- cell division control protein 42 homolog
- dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD))
- dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD))
- growth-regulating protein
- small GTP binding protein CDC42
- cell division cycle 42 homolog
- CDC42 GTP-binding protein
- Cell division control protein 42 homolog
- Cdc42 protein homolog
- fj62g06
- cell division control protein 42-like protein
- cell division cycle 42 (GTP binding protein, 25kDa)
- CG12530-PA
- CG12530-PB
- CG12530-PC
- CG12530-PD
- CG12530-PE
- CG12530-PF
- Cdc42-PA
- Cdc42-PB
- Cdc42-PC
- Cdc42-PD
- Cdc42-PE
- Cdc42-PF
- Cdc42-like
- likely rho family Ras-like GTPase
- cell division cycle 42
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