You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our MAPK3 Proteins (MAPK3)

Full name:
Mitogen-Activated Protein Kinase 3 Proteins (MAPK3)
On are 34 Mitogen-Activated Protein Kinase 3 (MAPK3) Proteins from 10 different suppliers available. Additionally we are shipping MAPK3 Antibodies (489) and MAPK3 Kits (47) and many more products for this protein. A total of 600 MAPK3 products are currently listed.
ATMAPK3, ATMPK3, Erk-1, Erk1, Ert2, Esrk1, fi06b09, HS44KDAP, HUMKER1A, MAPK1, mitogen-activated protein kinase 3, MNK1, Mtap2k, p44, p44-ERK1, p44-MAPK, p44erk1, p44mapk, Prkm3, T6D9.4, Tb08.10J17.940, wu:fi06b09, zERK1
list all proteins Gene Name GeneID UniProt
MAPK3 5595 P27361
MAPK3 26417 Q63844
MAPK3 50689 P21708

Show all synonyms

MAPK3 Proteins (MAPK3) by Origin

Select your origin of interest

Top referenced MAPK3 Proteins

  1. Human MAPK3 Protein expressed in Escherichia coli (E. coli) - ABIN667192 : Kim, Cochran: Extracellular signal-regulated kinase binds to TFII-I and regulates its activation of the c-fos promoter. in Molecular and cellular biology 2000 (PubMed)

More Proteins for MAPK3 Interaction Partners

Arabidopsis thaliana Mitogen-Activated Protein Kinase 3 (MAPK3) interaction partners

  1. Phosphatase AP2C1, as well as AP2C1-targeted MPK3 and MPK6 (show MAPK6 Proteins), are important regulators of plant-nematode interaction, where the co-ordinated action of these signalling components ensures the timely activation of plant defence.

  2. Results demonstrated the contribution of MPK3 and MPK6 (show MAPK6 Proteins) to riboflavin-induced resistance.

  3. These results indicate that the MVB pathway is positively regulated by pathogen-responsive MPK3/6 through LIP5 phosphorylation and plays a critical role in plant immune system

  4. MKK3-MPK6 is activated by blue light in a MYC2-dependent manner.

  5. MPK3 and MPK6 (show MAPK6 Proteins) target a subclass of 'VQ-motif'-containing proteins to regulate immune responses.

  6. MicroRNA biogenesis factor DRB1 (show EPHX1 Proteins) is a phosphorylation target of mitogen activated protein kinase (show MAPK1 Proteins) MPK3 in both rice and Arabidopsis

  7. MPK3 represses the constitutive and flg22-induced expression of defence genes in Arabidopsis thaliana.

  8. These results suggest that the MKK9-MPK3/MPK6 (show MAPK6 Proteins) cascade is part of the phosphate signaling pathway in plants.

  9. AZI1 overexpression in the mpk3 genetic background partially alleviates the salt-hypersensitive phenotype of this mutant, but functional MPK3 appears to be required for the full extent of AZI1-conferred robustness.

  10. HSFA4A is a substrate of the MPK3/MPK6 (show MAPK6 Proteins) signaling and that it regulates stress responses in Arabidopsis.

Cow (Bovine) Mitogen-Activated Protein Kinase 3 (MAPK3) interaction partners

  1. Chronic hypoxia induces Egr-1 via activation of ERK1/2 and contributes to pulmonary vascular remodeling.

  2. ER Ca(2+) release enhances eNOS Ser-635 phosphorylation and function via ERK1/2 activation.

  3. Thrombospondin 1 (show THBS1 Proteins), fibronectin (show FN1 Proteins), and vitronectin (show VTN Proteins) are differentially dependent upon RAS, ERK1/2, and p38 (show MAPK14 Proteins) for induction of vascular smooth muscle cell chemotaxis.

  4. results suggest that Nav1.7-Ca2+ influx-protein kinase C-alpha pathway activated ERK1/ERK2 and p38, which increased phosphorylation of glycogen synthase kinase-3beta, decreasing tau phosphorylation

  5. These data suggest that Gab1-ERK1/2 binding and their nuclear translocation play a crucial role in Egr-1 (show EGR1 Proteins) nuclear accumulation.

  6. data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt, mTOR, p70S6K, and ERK1/2.

  7. This study demonstrates for the first time that cyclic mechanical stretch induces the proliferation of bovine satellite cells and suppresses their myogenic differentiation through the activation of ERK (show MAPK1 Proteins).

  8. findings indicate that exposure to DHEA, at concentrations found in human blood, causes vascular endothelial proliferation by a plasma membrane-initiated activity that is Gi/o and ERK1/2 dependent.

  9. Results suggest that estrogen receptors and the ERK1/2 signaling pathway are involved in the anti-apoptotic action of LY117018 in vascular endothelial cells.

  10. The intracellular mechanism of action of CART in regulation of FSH (show BRD2 Proteins)-induced MAPK (show MAPK1 Proteins) signaling.

Candida albicans Mitogen-Activated Protein Kinase 3 (MAPK3) interaction partners

  1. Cek2 (show FGFR3 Proteins) has a cryptic role in cell-wall biogenesis and its role is not entirely redundant to Cek1.

  2. knockdown of SUV420H1 (show SUV420H1 Proteins) reduced phosphorylated ERK1 and total ERK1 proteins, and interestingly suppressed ERK1 at the transcriptional level

  3. Secreted aspartic protease-mediated proteolytic cleavage of Msb2 is required for activation of the Cek1 mitogen activated protein kinase (show MAPK1 Proteins) pathway in response to environmental cues.

  4. The authors propose that a Msb2, Cek1 and Ace2 signalling pathway addresses PMT genes as downstream targets and that different modes of regulation have evolved for PMT1 and PMT2/PMT4 genes.

  5. Msb2 is involved in the transmission of the signal toward Cek1 mediated by the Cdc42 (show CDC42 Proteins) GTPase (show RACGAP1 Proteins).

Zebrafish Mitogen-Activated Protein Kinase 3 (MAPK3) interaction partners

  1. ERK1/2-Akt1 (show AKT1 Proteins) crosstalk regulates arteriogenesis in mice and zebrafish.

  2. eena (show SH3GL1 Proteins) plays an important role in the development of the myeloid cell through activation of the ERK1/ERK2 (show MAPK1 Proteins) pathway

  3. ERK1 and ERK2 (show MAPK1 Proteins) target common and distinct gene sets, confirming diverse roles for these kinases during embryogenesis; for ERK1 different specific genes involved in dorsal-ventral patterning and subsequent embryonic cell migration were identified.

  4. These results demonstrate that induction of Hsp70 (show HSPA1A Proteins) in response to heat stress is dependent on ERK (show MAPK1 Proteins) activation in Pac2 (show PSMG2 Proteins) cells.

  5. Data define distinct roles for ERK1 and ERK2 (show MAPK1 Proteins) in developmental cell migration processes during zebrafish embryogenesis.

Human Mitogen-Activated Protein Kinase 3 (MAPK3) interaction partners

  1. ERK1-ERK2 (show MAPK1 Proteins) pathway plays a crucial role in cancer cell survival and proliferation and therefore represents an attractive target for anticancer therapy. (Review)

  2. MicroRNA-133b inhibits proliferation and invasion of ovarian cancer cells by inactivating Akt (show AKT1 Proteins) and Erk1/2 signaling and targeting EGFR (show EGFR Proteins).

  3. Letter: Interleukin-22 (show IL22 Proteins) inhibits tazarotene-induced gene 3 expression in keratinocytes via MAPK (show MAPK1 Proteins)-ERK1/2 and JAK2 (show JAK2 Proteins)/STAT3 (show STAT3 Proteins) signaling.

  4. Data indicate that the activation of extracellular-regulated protein kinase (show CDK7 Proteins) (ERK)1/2 as a downstream signal in the mitogenactivated protein kinase (show CDK7 Proteins) (MAPK (show MAPK1 Proteins)) pathway during cytokine production and apoptosis.

  5. results demonstrate that PSMC5 (show PSMC5 Proteins) is a new and important player involved in regulating ERK1/2 signal transmission through the remodeling of Shoc2 (show SHOC2 Proteins) scaffold complex in a spatially-defined manner.

  6. It was shown that newly synthesized H2O2 invigorates the phosphorylation and action of ERK-1/Erk2 (show MAPK1 Proteins) in E. coli phagocytosis, while phospho-JNK (show MAPK8 Proteins) and phospho-p38 (show CRK Proteins) appear to regulate H2O2 production.

  7. Opioid receptor delta-mediated activation of ERK1/2 is via ligand-specific transactivation of EGFR (show EGFR Proteins).

  8. The Asian-American variant of human papillomavirus type 16 exhibits higher activation of MAPK (show MAPK1 Proteins) and PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins) signaling pathways, transformation, migration and invasion of primary human keratinocytes.

  9. Study highlights the potential role of CCM3 (show PDCD10 Proteins) in regulating tight junction complex organization and brain endothelial barrier permeability through CCM3 (show PDCD10 Proteins)-ERK1/2-cortactin (show CTTN Proteins) cross-talk

  10. Endocytosis separates EGF (show EGF Proteins) receptors from endogenous fluorescently labeled HRas (show HRAS Proteins) and diminishes receptor signaling to MAP kinases in endosomes.

Mouse (Murine) Mitogen-Activated Protein Kinase 3 (MAPK3) interaction partners

  1. ERK (show EPHB2 Proteins) contributes to the morphine-induced hyperalgesia by regulating the activation of c-JUN (show JUN Proteins)

  2. Consistent with the essential role of ERK1/2 during macrophage differentiation and defects of macrophagic differentiation in native ERK1(-/-) progenitors, ERK (show EPHB2 Proteins) signaling is strongly activated in Eger/Fms (show CSF1R Proteins) cells upon M-CSF (show CSF1R Proteins)-induced macrophage differentiation.

  3. CXCR4 inhibitor attenuates allergen-induced lung inflammation by down-regulating MMP-9 and ERK1/2 expression.

  4. Myocardial FasL expression in mice activates differential robust fibrotic, apoptotic and inflammatory responses via ERK1/2 in cardiomyocytes and cardiac fibroblasts inducing dilated cardiomyopathy/heart failure.

  5. Cx43 regulates FGF10-induced ERK1/2 phosphorylation in salivary epithelium.

  6. ERK1/2 plays an important role in TGF-beta1 (show TGFB1 Proteins)-induced mTOR (show FRAP1 Proteins) activation and translational regulation of Nox4 (show NOX4 Proteins) protein.

  7. T1R1/T1R3 have roles in regulating ERK1/2 and mTORC1 in MIN6 cells

  8. ERK/GSK3beta signaling was involved in the apoptotic and G1 phase arrest effects of AT-I in melanoma cells.

  9. These results suggest that in addition to the Mos (show MOS Proteins)-MEK1 (show MAP2K1 Proteins)/2 pathway, the Mos (show MOS Proteins)-mediated p38 (show CRK Proteins) pathway may be implicated in metaphase-II arrest.

  10. The role of ERK1 and ERK2 (show MAPK1 Proteins) in chondrocyte terminal differentiation, was investigated.

Pig (Porcine) Mitogen-Activated Protein Kinase 3 (MAPK3) interaction partners

  1. Treatment with ERK inhibitors or ERK1/2 knockdown significantly suppressed porcine epidemic diarrhea virus progeny production.

  2. This study reveals a new function of the gE glycoprotein of pseudorabies virus and suggests that pseudorabies virus, through activation of ERK1/2 signaling, has a substantial impact on T cell behavior.

  3. CSF2 (show CSF2 Proteins) stimulates proliferation of trophectoderm cells by activation of the PI3K-and ERK1/2 MAPK (show MAPK1 Proteins)-dependent MTOR (show FRAP1 Proteins) signal transduction cascades.

  4. PGRN (show GRN Proteins) inhibits adipogenesis in porcine preadipocytes partially through ERK (show MAPK1 Proteins) activation mediated PPARgamma (show PPARG Proteins) phosphorylation.

  5. Porcine circovirus type 2 (PCV2) might induce autophagy via the AMPK (show PRKAA1 Proteins)/ERK (show MAPK1 Proteins)/TSC2/mTOR (show FRAP1 Proteins) signaling pathway in the host cells, representing a pivotal mechanism for PCV2 pathogenesis

  6. Data show that proinflammatory cytokines induction was ERK1/2 and JNK1 (show MAPK8 Proteins)/2 dependent.

  7. Saccharomyces cerevisiae inhibits the Enterotoxigenic Escherichia coli-induced expression of pro-inflammatory transcripts and this inhibition was associated to a decrease of ERK1/2 and p38 MAPK (show MAPK14 Proteins) phosphorylation

  8. ERK1 phosphorylation in response to Insulin-like Growth Factor-1 (show IGF1 Proteins) does not require activation of the Insulin-like Growth Factor-1 receptor tyrosine kinase (show IGF1R Proteins)

  9. Retinal ischemia-reperfusion alters expression of mitogen-activated protein kinases, particularly ERK1/2, in the neuroretina and retinal arteries.

  10. Cyclosporine A/sirolimus alter claudin-1 expression in renal proximal tubular cells via ERK1/2 signaling pathway to alter barrier function.

MAPK3 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.

Alternative names and synonyms associated with MAPK3

  • mitogen-activated protein kinase 3 (MPK3)
  • mitogen-activated protein kinase 3 (MAPK3)
  • MAP kinase-like orf; aka CEK1; one of two protein kinase genes similar to S. cerevisiae MAP kinases FUS3 (YBL016W) and KSS1 (YGR040W) involved in pheromone signal transduction (ERK1)
  • mitogen-activated protein kinase 3 (Mapk3)
  • mitogen-activated protein kinase 3 (mapk3)
  • mitogen activated protein kinase 3 (Mapk3)
  • mitogen-activated protein kinase 3 (Tb927.8.3550)
  • mitogen-activated protein kinase 3 (Tc00.1047053509475.10)
  • ATMAPK3 protein
  • ATMPK3 protein
  • Erk-1 protein
  • Erk1 protein
  • Ert2 protein
  • Esrk1 protein
  • fi06b09 protein
  • HS44KDAP protein
  • HUMKER1A protein
  • MAPK1 protein
  • mitogen-activated protein kinase 3 protein
  • MNK1 protein
  • Mtap2k protein
  • p44 protein
  • p44-ERK1 protein
  • p44-MAPK protein
  • p44erk1 protein
  • p44mapk protein
  • Prkm3 protein
  • T6D9.4 protein
  • Tb08.10J17.940 protein
  • wu:fi06b09 protein
  • zERK1 protein

Protein level used designations for MAPK3

extracellular signal-regulated kinase 1 , likely protein kinase , MAP kinase isoform p44 , MAPK 1 , extracellular signal-related kinase 1 , insulin-stimulated MAP2 kinase , microtubule-associated protein 2 kinase , MAP kinase 3 , p44 MAP kinase , pp42/MAP kinase , MAP kinase 1 , MAPK 3 , mitogen-activated 3 , mitogen-activated protein kinase 1 , mitogen-activated protein kinase 3 , extracellular signal-regulated kinase-1

823706 Arabidopsis thaliana
531391 Bos taurus
3642789 Candida albicans SC5314
479790 Canis lupus familiaris
100725692 Cavia porcellus
399480 Danio rerio
100066173 Equus caballus
5595 Homo sapiens
26417 Mus musculus
50689 Rattus norvegicus
445013 Sus scrofa
3659358 Trypanosoma brucei brucei strain 927/4 GUTat10.1
3531528 Trypanosoma cruzi strain CL Brener
Selected quality suppliers for MAPK3 Proteins (MAPK3)
Did you look for something else?