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anti-Mouse (Murine) PPARG Antibodies:
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Human Polyclonal PPARG Primary Antibody for IF (p), IHC (p) - ABIN1387919
Kolli, Stechschulte, Dowling, Rahman, Czernik, Lecka-Czernik: Partial agonist, telmisartan, maintains PPAR? serine 112 phosphorylation, and does not affect osteoblast differentiation and bone mass. in PLoS ONE 2014
Show all 8 Pubmed References
Human Polyclonal PPARG Primary Antibody for WB - ABIN966886
Berger, Moller: The mechanisms of action of PPARs. in Annual review of medicine 2002
Show all 3 Pubmed References
Human Monoclonal PPARG Primary Antibody for IF, IHC - ABIN966887
Ahdjoudj, Kaabeche, Holy, Fromigué, Modrowski, Zérath, Marie: Transforming growth factor-beta inhibits CCAAT/enhancer-binding protein expression and PPARgamma activity in unloaded bone marrow stromal cells. in Experimental cell research 2004
Show all 3 Pubmed References
Human Monoclonal PPARG Primary Antibody for IF, ELISA - ABIN966888
Yang, Ma, Ma, Fogo: Peroxisome proliferator-activated receptor-gamma agonist is protective in podocyte injury-associated sclerosis. in Kidney international 2006
Show all 3 Pubmed References
Human Monoclonal PPARG Primary Antibody for ELISA, WB - ABIN969358
Canizales-Quinteros, Aguilar-Salinas, Ortiz-López, Rodríguez-Cruz, Villarreal-Molina, Coral-Vázquez, Huertas-Vázquez, Hernández-Caballero, López-Alarcón, Brito-Zurita, Domínguez-Banda et al.: Association of PPARG2 Pro12Ala variant with larger body mass index in Mestizo and Amerindian populations of Mexico. ... in Human biology 2007
Show all 2 Pubmed References
Chicken Polyclonal PPARG Primary Antibody for IHC, IHC (p) - ABIN266771
Mattace Raso, Simeoli, Russo, Iacono, Santoro, Paciello, Ferrante, Canani, Calignano, Meli: Effects of sodium butyrate and its synthetic amide derivative on liver inflammation and glucose tolerance in an animal model of steatosis induced by high fat diet. in PLoS ONE 2013
Show all 2 Pubmed References
Human Polyclonal PPARG Primary Antibody for FACS, IF (p) - ABIN1386283
Sun, Zeng, Cao, Song, Zhang, Liu: Vibration Training Triggers Brown Adipocyte Relative Protein Expression in Rat White Adipose Tissue. in BioMed research international 2015
Human Polyclonal PPARG Primary Antibody for ELISA - ABIN105800
Bruedigam, Koedam, Chiba, Eijken, van Leeuwen: Evidence for multiple peroxisome proliferator-activated receptor gamma transcripts in bone: fine-tuning by hormonal regulation and mRNA stability. in FEBS letters 2008
Human Polyclonal PPARG Primary Antibody for ELISA, WB - ABIN562333
Le Mée, Hennebert, Ferrec, Wülfert, Morfin: 7beta-Hydroxy-epiandrosterone-mediated regulation of the prostaglandin synthesis pathway in human peripheral blood monocytes. in Steroids 2008
Human Polyclonal PPARG Primary Antibody for IF (p), IHC (p) - ABIN703405
Mölzer, Wallner, Kern, Tosevska, Schwarz, Zadnikar, Doberer, Marculescu, Wagner: Features of an altered AMPK metabolic pathway in Gilbert's Syndrome, and its role in metabolic health. in Scientific reports 2016
Pin1 (show PIN1 Antibodies) enhances adipocyte differentiation by regulating the function of PPARgamma.
The authors report that macrophage PPARgamma deletion in mice not only exacerbates mammary tumor development but also impairs the anti-tumor effects of rosiglitazone. Mechanistically, the authors identify Gpr132 (show GPR132 Antibodies) as a novel direct PPARgamma target in macrophage whose expression is enhanced by PPARgamma loss but repressed by PPARgamma activation.
Data indicate that obesity-induced insulin (show INS Antibodies) resistance and lipotoxicity can be treated with ginsenoside Rg3, which acts though the STAT5 (show STAT5A Antibodies)-PPAR gamma pathway in vivo and in vitro.
TAK1 (show NR2C2 Antibodies) is required for PPARgamma transactivation and promotes PPARgamma transcriptional activity synergistically with TAK1 binding protein 1 (TAB1 (show TAB1 Antibodies)).
PPAR gamma role in fat deposition and body weight gain.PPAR gamma is regulated by miR (show MLXIP Antibodies)-27b.
These findings demonstrated that apigenin could prevent the D-GalN (show GAL Antibodies)/LPS (show TLR4 Antibodies)-induced liver injury in mice, and its mechanisms might be associated with the increments of Nrf-2 (show NFE2L2 Antibodies)-mediated antioxidative enzymes and modulation of PPARgamma/NF-kappaB (show NFKB1 Antibodies)-mediated inflammation.
Time course analysis demonstrated that the adipogenic 'hub', sampled by PPARgamma and Lpin1 (show LPIN1 Antibodies), undergoes orchestrated reorganization during adipogenesis.
Aleglitazar protects cardiomyocytes against hyperglycaemia-induced apoptosis by combined activation of both peroxisome proliferator-activated receptor-alpha (show PPARA Antibodies) and peroxisome proliferator-activated receptor-gamma.
IRF6 (show IRF6 Antibodies) suppresses PPARgamma through binding IRF (show TRIM63 Antibodies) recognition sites located upstream of the PPARgamma coding region. Taken together, the results suggest that an IRF6 (show IRF6 Antibodies)/PPARgamma regulatory axis suppresses anti-inflammatory responses in bone marrow-derived macrophages and provides references for future study addressing dysregulated metabolic and immunologic homeostasis of obese adipose tissue.
NFIA (show NFIA Antibodies) activates the cell-type-specific enhancers and facilitates the binding of PPARgamma to control the brown fat gene program.
Immune cell-infiltration is controlled by activated peroxisome proliferator activated receptor gamma (PPARgamma)/retinoid X receptor alpha (RXRalpha (show RXRA Antibodies)) that inhibits expression/secretion of inflammatory cytokines.
Results show that resistin (show RETN Antibodies) down-regulates the transcription of GLUT1 (show SLC2A1 Antibodies) by suppressing the expression of PPARG, thus causing impaired glucose transportation in endothelial cell layers.
these studies demonstrate that PPARgamma is an important modulator of MUC16 (show MUC16 Antibodies) expression.
a panel of proteins correlated with PPARgamma expression that could be associated with colorectal cancer, was identified.
We propose a novel role of the miR (show MLXIP Antibodies)-27a/PPARgamma/beta-catenin (show CTNNB1 Antibodies) axis in fostering the progression toward more deteriorated podocyte injury in diabetic nephropathy (DN). Targeting miR (show MLXIP Antibodies)-27a could be a potential therapeutic approach for DN.
the presented cPCA mapping of the PPARg-ligand complexes may guide in silico drug discovery programs seeking to avoid stabilization of helix 12 in their development of partial- and non-agonistic PPARg ligands.
The presence of the PPARgamma (Pro12Ala) SNP did not modify the association between inorganic arsenic methylation capacity and breast cancer.
COX-2 (show COX2 Antibodies) is a potential marker for identifying high-risk sebaceous gland carcinoma (SGC (show SGCB Antibodies)) patients. Expression of PPAR-gamma in eyelid SGC (show SGCB Antibodies) cases reflects terminal sebaceous differentiation.
PAK4 (show PAK4 Antibodies) downregulation decreased PPARgamma-mediated Nox1 (show NOX1 Antibodies) expression and suppressed EMT (show ITK Antibodies) in IR-treated glioma cells.
The results suggest the higher expression of miR (show MYLIP Antibodies)-130a, which targeting peroxisome proliferator-activated receptor gamma, may be the reason for less fat deposition in intramuscular adipose tissue than subcutaneous adipose tissue.
The immunoprecipitation results also showed that high AA concentrations significantly increased the interaction of mTOR (show FRAP1 Antibodies) and PPARg. In summary, PPARg plays an important role in the regulation of IGF-1 (show IGF1 Antibodies) secretion and gene expression in response to dietary protein.
The regulatory role of microRNA miR (show MYLIP Antibodies)-27b-3p on peroxisome proliferator-activated receptor-gamma (PPARgamma) was confirmed by their inversed expression patterns in oocytes: [miR (show MYLIP Antibodies)-27b-3p]
an Enhancer box and a binding site for a cooperative co-activator of MyoD (show MYOD1 Antibodies) are present in the promoter region of porcine PPARgamma.
The data suggest that there is local cooperation between resistin (show RETN Antibodies) and PPARgamma expression in the porcine ovary. Resistin (show RETN Antibodies) significantly increased the expression of PPARgamma, whereas PPARgamma decreased resistin (show RETN Antibodies) expression; thus, PPARgamma is a new key regulator of resistin (show RETN Antibodies) expression and function.
Therefore, this study demonstrated that the different regulatory adipogenic roles of MSTN (show MSTN Antibodies) in ADSCs and MSCs act by differentially regulating PPARgamma and MyoD (show MYOD1 Antibodies) expression.
PGRN (show GRN Antibodies) inhibits adipogenesis in porcine preadipocytes partially through ERK (show MAPK1 Antibodies) activation mediated PPARgamma phosphorylation.
Resveratrol activated sirtuin 1 (Sirt1 (show SIRT1 Antibodies)) gene expression and increased adipose triglyceride lipase (ATGL (show PNPLA2 Antibodies)) gene expression and glycerol release. Furthermore, this study found the opposite Sirt1 (show SIRT1 Antibodies) regulation pattern for PPARgamma to that of ATGL (show PNPLA2 Antibodies) in adipocytes.
The results indicate that the endometrial expression of PPARgamma genes fluctuates during the estrous cycle and pregnancy.
Increasing dietary DE linearly enhanced the expression of PPARgamma in adipose tissues but not skeletal muscle of Rongchang piglets.
These results indicated that docosahexaenoic acid may attenuate lipopolysaccharide-stimulated inflammatory response in bovine mammary epithelial cells by suppressing NF-kappaB (show NFKB1 Antibodies) activation through a mechanism partly dependent on PPARgamma activation.
PPARgamma is a positive regulator of milk fat synthesis in dairy cow mammary epithelial cells.
An Asp7Gly substitution in PPARG is associated with adiposity.
upregulation of PPARgamma was observed in the backfat tissue of Lilu cattle with increasing age
Co-culture of adipocytes and myoblasts elicited an increase in C/EBPbeta (show CEBPB Antibodies) and PPAR-gamma gene expression in differentiated myoblasts and an increase in GPR43 (show FFAR2 Antibodies) gene expression in adipocytes.
A potential association of an single nucleotide polymorphism (72472 GT in exon7) of the bovine PPAR-gamma gene with carcass and meat quality traits, was evaluated.
study demonstrates the co-expression of DLX3 (show DLX3 Antibodies), PPARG and SP1 (show SP1 Antibodies) in trophoblast binucleated cell(BNC)nuclei; this suggests a possible role of these transcription factors through BNC specific genes at the time of pre-placental differentiation
Single nucleotide polymorphisms in coding region of the PPARgamma gene, were examined.
oxidative stress attenuates PPAR gamma expression and activity in vascular endothelial cells
The effects of dietary fat components on the expression of PPAR-gamma AND PPAR-gamma coactivator 1 (show PPARGC1A Antibodies) in cultured bovine preadipocytes are reported.
study found PPAR-gamma expression was prominent in the subthalamic nucleus, oculomotor nucleus, ventral tegmental nucleus, and to a lesser extent, in the putamen; 3 or 12 months after MPTP (show PTPN2 Antibodies), only the lesioned putamen had increased PPAR-gamma
Aleglitazar, a dual PPARalpha (show PPARA Antibodies)/gamma agonist, has beneficial effects on both lipid and glucose parameters in a primate model of the metabolic syndrome.
siRNA targeting PPARgamma gene can inhibit adipogenic differentiation of BMSCs and prevent steroid-induced osteonecrosis in rabbit.
vitamin E supplementation affords protection by decreasing MMP-1 (show MMP1 Antibodies) and increasing PPARg, GSTa (show GSTa2 Antibodies), and ABCA1 (show ABCA1 Antibodies) levels in aortae of rabbits fed a cholesterol-rich diet
Telmisartan improves microvascular dysfunction during myocardial ischemia/reperfusion injury via the PPARgamma pathway.
PPARgamma plays a luteotropic role in pseudopregnant rabbits, through PTGS2 (show PTGS2 Antibodies) down-regulation and 3beta-HSD (show HAL Antibodies) up-regulation, with a consequent PGF2alpha decrease and progesterone increase.
In an animal model of atherosclerosis, the expression of PPAR-gamma is upregulated following atorvastatin administration.
Tongxinluo can inhibit the expression of MMP-3 (show MMP3 Antibodies) and 9 and increase the expression of PPARgamma in atherosclerotic rabbits.
Niacin Reduces serum level and adipose mRNA expression of leptin (show LEP Antibodies) and up-regulates PPARgamma and CD36 (show CD36 Antibodies) mRNA expression in hypercholesterolemic rabbits.
Antidiabetic drug pioglitazone protects the heart via activation of PPAR-gamma receptors, PI3-kinase (show PIK3CA Antibodies), Akt (show AKT1 Antibodies), and eNOS (show NOS3 Antibodies) pathway in a rabbit model of myocardial infarction.
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.
peroxisome proliferator activated receptor gamma
, peroxisome proliferative activated receptor gamma
, peroxisome proliferator-activated receptor gamma
, peroxisome proliferator activator receptor gamma
, nuclear receptor subfamily 1 group C member 3
, peroxisome proliferator activated receptor gamma 2
, peroxisome proliferator activated receptor gamma 4
, Nuclear receptor subfamily 1 group C member 3
, PPAR gamma
, peroxisome proliferator-activated nuclear receptor gamma variant 1
, peroxisome proliferator-activated receptor gamma 1
, peroxisome proliferator activator receptor, gamma
, PPAR gamma 2
, xPPAR gamma
, peroxisome proliferative activated receptor, gamma
, peroxisome proliferator-activated receptor gamma 2
, peroxisome proliferator-activated receptor gamma 1-a
, peroxisome proliferator-activated receptor gamma 1-b
, PPAR gamma 1
, peroxisome proliferator activated receptor gamma-1
, peroxisome proliferator-activated receptor-gamma