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Browse our anti-RYR2 (RYR2) Antibodies

Full name:
anti-Ryanodine Receptor 2 (Cardiac) Antibodies (RYR2)
On www.antibodies-online.com are 36 Ryanodine Receptor 2 (Cardiac) (RYR2) Antibodies from 12 different suppliers available. Additionally we are shipping RYR2 Kits (7) and many more products for this protein. A total of 47 RYR2 products are currently listed.
Synonyms:
9330127I20Rik, ARVC2, ARVD2, RyR, RYR-2, RYR2, VTSIP

Most Popular Reactivities for anti-RYR2 (RYR2) Antibodies

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anti-Human RYR2 Antibodies:

anti-Rat (Rattus) RYR2 Antibodies:

anti-Mouse (Murine) RYR2 Antibodies:

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More Antibodies against RYR2 Interaction Partners

Rabbit Ryanodine Receptor 2 (Cardiac) (RYR2) interaction partners

  1. Two regions of the ryanodine receptor (show RYR3 Antibodies) calcium channel are involved in Ca(2 (show CA2 Antibodies)+)-dependent inactivation

  2. [REVIEW] The efficacy of divalent calcium ion (Ca2 (show CA2 Antibodies)+) release in the myocardium depends on the amount of Ca2 (show CA2 Antibodies)+ loaded into the Ca2 (show CA2 Antibodies)+ store and the way in which this Ca2 (show CA2 Antibodies)* load influences the activity of the ryanodine receptor (show RYR3 Antibodies) Ca2+ release channel (RyR2).

  3. There were substantial transmural gradients in Cav1.2 (show CACNA1C Antibodies), KChIP2 (show KCNIP2 Antibodies), ERG (show KCNH2 Antibodies), KvLQT1 (show KCNQ1 Antibodies), Kir2.1 (show KCNJ2 Antibodies), NCX1 (show SLC8A1 Antibodies), SERCA2a (show ATP2A2 Antibodies) and RyR2 at the mRNA and, in some cases, protein level-in every case the mRNA or protein was more abundant in the epicardium than the endocardium.

  4. phosphorylation and K201 acted similarly to change the conformation of RyR1 (show RYR1 Antibodies)/2 and regulate FKBP12 (show FKBP1A Antibodies)/12.6 binding.

Human Ryanodine Receptor 2 (Cardiac) (RYR2) interaction partners

  1. Long-Term Prognosis of Catecholaminergic Polymorphic Ventricular Tachycardia Patients With Ryanodine Receptor (show RYR3 Antibodies) (RYR2) Mutations.

  2. Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) Associated With Ryanodine Receptor (show RYR3 Antibodies) (RyR2) Gene Mutations- Long-Term Prognosis After Initiation of Medical Treatment.

  3. Genotype may predict phenotype in catecholaminergic polymorphic ventricular tachycardia, including a higher risk of life-threatening cardiac events in subjects with variants in the C-terminus of ryanodine receptor-2 (RyR2). [review]

  4. RYR2 C2277R mutation is a cause of catecholaminergic polymorphic ventricular tachycardia in a family with high lethality in younger individuals.

  5. RYR2, PTDSS1 (show PTDSS1 Antibodies) and AREG (show AREG Antibodies) are autism susceptibility genes that are implicated in a Lebanese population-based study of copy number variations in this disease.

  6. Studies indicate that the ryanodine receptors (RyRs: RyR1 (show RYR1 Antibodies), RyR2, RyR3 (show RYR3 Antibodies)) and inositol 1,4,5-trisphosphate receptors (IP3Rs: IP3R1 (show ITPR1 Antibodies), IP3R2 (show ITPR2 Antibodies), IP3R3 (show ITPR3 Antibodies)) are the major Ca(2 (show CA2 Antibodies)+) release channels (CRCs) on the endo/sarcoplasmic reticulum (ER/SR).

  7. although the EF-hand domain is not required for RyR2 activation by cytosolic Ca(2 (show CA2 Antibodies)+), it plays an important role in luminal Ca(2 (show CA2 Antibodies)+) activation and SOICR

  8. Half of the RYR2 mutations in catecholaminergic polymorphic ventricular tachycardia cohort were de novo, and most of the remaining mutations were inherited from mothers.

  9. A deletion of exon 3 of the RYR2 gene was found in a family with catecholaminergic polymorphic ventricular tachycardia.

  10. G357S_RyR2 mutation in the cardiac ryanodine receptor was identified in 179 family members with Catecholaminergic polymorphic ventricular tachycardia and in 6 Sudden cardiac death cases.

Mouse (Murine) Ryanodine Receptor 2 (Cardiac) (RYR2) interaction partners

  1. these results suggest that neuronal RyR2 Ca(2 (show CA2 Antibodies)+) leak due to Calstabin2 (show FKBP1B Antibodies) deletion contributes to learning deficiency and memory impairment.

  2. Nav1.5 (show SCN5A Antibodies) is downregulated and INa (show INA Antibodies) is reduced in RyR2-P2328S ventricles.

  3. The minimal KEKE motif of TRN (show TNPO1 Antibodies) involved in the interactions with CSQ2, HRC (show HRC Antibodies) and RyR2 within the Ca2 (show CA2 Antibodies)+ release units of cardiac sarcoplasmic reticulum has been defined.

  4. Inhibition of RyR2 phosphorylation can suppress sarcoplasmic reticulum Ca(2 (show CA2 Antibodies)+) leak in mdx (show DMD Antibodies) mouse hearts in part by reducing RyR2 oxidation.

  5. Interacting network of the gap junction protein connexin43 (show GJA1 Antibodies), which includes Ryr2 and Cox1 (show COX1 Antibodies), is modulated by ischemia and reperfusion in the heart.

  6. While CASQ2 (show CASQ2 Antibodies) stabilizes RyR2 rendering it refractory in the diastolic phase, HRC (show HRC Antibodies) enhances RyR2 activity facilitating RyR2 recovery from refractoriness.

  7. These results provide no evidence that the H29D mutation enhances the cytosolic Ca2 (show CA2 Antibodies)+ activation of RyR2.

  8. CaMK2d (show CAMK2B Antibodies)-dependent phosphorylation of RyR2-S2814 is significant in cardiomyopathy, independent of hypertrophy, induced by prolonged beta-adrenergic receptor stimulation.

  9. RyR2 activity determines the potency of open-state blockers flecainide and R-propafenone for suppressing arrhythmogenic Ca2 (show CA2 Antibodies)+ waves in cardiomyocytes.

  10. Flecainide (1 mum) rescues the RyR2-P2328S atrial arrhythmogenic phenotype by restoring compromised INa (show INA Antibodies) and lambda, changes recently attributed to increased sarcoplasmic reticular Ca(2 (show CA2 Antibodies)+) release.

RYR2 Antigen Profile

Antigen Summary

This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia.

Alternative names and synonyms associated with RYR2

  • ryanodine receptor 2 (cardiac) (RYR2) antibody
  • ryanodine receptor 2-like (LOC537376) antibody
  • cardiac ryanodine receptor (RYR-2) antibody
  • ryanodine receptor 2 (cardiac) (Ryr2) antibody
  • ryanodine receptor 2, cardiac (Ryr2) antibody
  • 9330127I20Rik antibody
  • ARVC2 antibody
  • ARVD2 antibody
  • RyR antibody
  • RYR-2 antibody
  • RYR2 antibody
  • VTSIP antibody

Protein level used designations for RYR2

cardiac muscle ryanodine receptor , ryanodine receptor 2 (cardiac) , ryanodine receptor 2-like , Ca2+ release channel , cardiac muscle ryanodine receptor-calcium release channel , cardiac muscle-type ryanodine receptor , ryanodine receptor 2 , type 2 ryanodine receptor , cardiac ryanodine receptor 2 , cardiac-type ryanodine receptor , islet-type ryanodine receptor , kidney-type ryanodine receptor , ryanodine receptor type II , calcium release channel , ryanodine receptor type 2

GENE ID SPECIES
457846 Pan troglodytes
100028207 Monodelphis domestica
100057437 Equus caballus
100406916 Callithrix jacchus
537376 Bos taurus
100009536 Oryctolagus cuniculus
403615 Canis lupus familiaris
100731307 Cavia porcellus
6262 Homo sapiens
689560 Rattus norvegicus
20191 Mus musculus
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