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RYR2 antibody (AA 901-1192) (FITC)

RYR2 Reactivity: Human Host: Rabbit Polyclonal FITC
Catalog No. ABIN7168511
  • Target See all RYR2 Antibodies
    RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))
    Binding Specificity
    • 12
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 901-1192
    Reactivity
    • 26
    • 18
    • 18
    • 3
    Human
    Host
    • 25
    • 1
    Rabbit
    Clonality
    • 25
    • 1
    Polyclonal
    Conjugate
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RYR2 antibody is conjugated to FITC
    Application
    Please inquire
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Ryanodine receptor 2 protein (901-1192AA)
    Isotype
    IgG
    Top Product
    Discover our top product RYR2 Primary Antibody
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))
    Alternative Name
    RYR2 (RYR2 Products)
    Synonyms
    RYR2 antibody, ARVC2 antibody, ARVD2 antibody, RYR-2 antibody, RyR antibody, VTSIP antibody, 9330127I20Rik antibody, ryanodine receptor 2 antibody, ryanodine receptor 2, cardiac antibody, RYR2 antibody, Ryr2 antibody
    Background

    Background: Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca(2+) levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development.

    Aliases: ARVC2 antibody, ARVD2 antibody, Cardiac muscle ryanodine receptor antibody, Cardiac muscle ryanodine receptor-calcium release channel antibody, hRYR-2 antibody, ryanodine receptor 2 (cardiac) antibody, Ryanodine receptor 2 antibody, RyR antibody, RYR-2 antibody, RyR2 antibody, RYR2_HUMAN antibody, Type 2 ryanodine receptor antibody, VTSIP antibody

    UniProt
    Q92736
    Pathways
    Myometrial Relaxation and Contraction
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