RYR2 antibody (AA 4850-4950)

Catalog No. ABIN1513493

The Rabbit Polyclonal anti-RYR2 antibody is suitable to detect RYR2 in samples from Human. It has been validated for WB and IF.

Quick Overview for RYR2 antibody (AA 4850-4950) (ABIN1513493)

Target: RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RYR2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-RYR2 Antibody

Binding Specificity: AA 4850-4950

Sequence: FFFFVIVILL AIIQGLIIDA FGELRDQQEQ VKEDMETKCF ICGIGNDYFD TVPHGFETHT LQEHNLANYL FFLMYLINKD ETEHTGQESY VWKMYQERCW E

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 4850-4950 of human RYR2 (NP_001026.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RYR2

Target: RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))

Alternative Name: RYR2

Background: This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia.,RYR2,ARVC2,ARVD2,RYR-2,RyR,VTSIP,RYR2,Cancer,Signal Transduction,Endocrine & Metabolism,Neuroscience,Calcium Signaling,Cardiovascular,Hypoxia,Heart,Contractility,Cardiac arrhythmias,RYR2

Molecular Weight: 564 kDa/565 kDa

Gene ID: 6262

UniProt: Q92736

Pathways: Myometrial Relaxation and Contraction