Browse our anti-PDE8B (PDE8B) Antibodies

Full name:
anti-phosphodiesterase 8B Antibodies (PDE8B)
On are 49 phosphodiesterase 8B (PDE8B) Antibodies from 13 different suppliers available. Additionally we are shipping and many more products for this protein. A total of 53 PDE8B products are currently listed.
ADSD, B230331L10Rik, C030047E14Rik, PDE8B, PPNAD3, RNPDE8B
list all antibodies Gene Name GeneID UniProt
PDE8B 8622 O95263
PDE8B 218461  
PDE8B 309962  

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anti-Human PDE8B Antibodies:

anti-Mouse (Murine) PDE8B Antibodies:

anti-Rat (Rattus) PDE8B Antibodies:

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Top referenced anti-PDE8B Antibodies

  1. Mouse (Murine) Polyclonal PDE8B Primary Antibody for WB - ABIN1881646 : Horvath, Faucz, Finkielstain, Nikita, Rothenbuhler, Almeida, Mericq, Stratakis: Haplotype analysis of the promoter region of phosphodiesterase type 8B (PDE8B) in correlation with inactivating PDE8B mutation and the serum thyroid-stimulating hormone levels. in Thyroid : official journal of the American Thyroid Association 2010 (PubMed)
    Show all 3 references for 1881646

More Antibodies against PDE8B Interaction Partners

Human phosphodiesterase 8B (PDE8B) interaction partners

  1. a heterozygous nonsense mutation in the first exon of cyclic nucleotide phosphodiesterase (show PDE3B Antibodies) 8B gene, which is predicted to disrupt all important functional domains of the cyclic nucleotide phosphodiesterase (show PDE3B Antibodies) 8B protein, in two members of family with autosomal-dominant striatal degeneration

  2. Genetic variation of the PDE8B gene may be involved in the etiology of subclinical hypothyroidism in pregnant women.

  3. A prevalence of the minor allele of PDE8B gene polymorphism associated with elevated serum levels of TSH was demonstrated in patients affected by sporadic nonautoimmune subclinical hypothyroidism.

  4. rs4704397 in phosphodiesterase 8B is associated with thyrotropin and thyroid hormone (show PTH Antibodies) concentrations

  5. There is an association between homozygous A/A as well as homozygous G/G carriers of SNP rs 4704397 in PDE8B and recurrent miscarriage.

  6. PDE8B gene polymorphisms may be correlated with hyperthyroxinemia in the Chinese Han population.

  7. PDE8B is another PDE (show ALDH7A1 Antibodies) gene in which variations may contribute to predisposition of adrenocortical tumours.

  8. In obese children, PDE8B is associated with TSH; the interaction between adiposity and PDE8B on TSH is not synergistic, but follows an additive model.

  9. Common genetic variation in PDE8B is associated with reciprocal changes in thyroid hormone (show PTH Antibodies) levels.

  10. Our analysis revealed separate segregation of an inactivating PDE8B allele from the high-TSH-allele and showed low TSH levels in persons who carry an inactivating PDE8B allele. These data suggest that PDE8B may be involved in regulation of TSH levels.

Mouse (Murine) phosphodiesterase 8B (PDE8B) interaction partners

  1. Pde8b knockout mice demonstrate improvement in select behaviors, motor-coordination, attenuation of age-induced motor coordination decline and increased anxiety levels.

  2. findings suggest that both PDE8A (show PDE8A Antibodies) and PDE8B play essential roles to maintain low cAMP levels, thereby suppressing resting steroidogenesis by keeping CEH (show EPHX2 Antibodies)/HSL (show LIPE Antibodies) inactive and StAR protein expression low

  3. Phosphodiesterase 8B is a major regulator of pools of cyclic AMP (show TMPRSS5 Antibodies) that promote steroidogenesis.

PDE8B Antigen Profile

Antigen Summary

The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with PDE8B

  • phosphodiesterase 8B (PDE8B) antibody
  • phosphodiesterase 8B (pde8b) antibody
  • phosphodiesterase 8B (Pde8b) antibody
  • ADSD antibody
  • B230331L10Rik antibody
  • C030047E14Rik antibody
  • PDE8B antibody
  • PPNAD3 antibody
  • RNPDE8B antibody

Protein level used designations for PDE8B

phosphodiesterase 8B , high-affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B , high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B-like , 3',5' cyclic nucleotide phosphodiesterase 8B , cell proliferation-inducing gene 22 protein , high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B , hsPDE8B , cAMP-specific cyclic nucleotide phosphodiesterase PDE8

427645 Gallus gallus
461796 Pan troglodytes
488939 Canis lupus familiaris
539768 Bos taurus
100020085 Monodelphis domestica
100073273 Equus caballus
100386134 Callithrix jacchus
100449849 Pongo abelii
100468338 Ailuropoda melanoleuca
100490787 Xenopus (Silurana) tropicalis
100522306 Sus scrofa
100542722 Meleagris gallopavo
100565292 Anolis carolinensis
100581907 Nomascus leucogenys
8622 Homo sapiens
218461 Mus musculus
309962 Rattus norvegicus
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