Browse our anti-MUC1 (MUC1) Antibodies

Full name:
anti-Mucin 1, Cell Surface Associated Antibodies (MUC1)
On www.antibodies-online.com are 1441 Mucin 1, Cell Surface Associated (MUC1) Antibodies from 38 different suppliers available. Additionally we are shipping MUC1 Kits (104) and MUC1 Proteins (53) and many more products for this protein. A total of 1628 MUC1 products are currently listed.
Synonyms:
CA 15-3, CD227, EMA, H23AG, KL-6, MAM6, MCKD1, Muc-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM
list all antibodies Gene Name GeneID UniProt
MUC1 4582 P15941
MUC1 24571  
MUC1 17829 Q02496

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Top referenced anti-MUC1 Antibodies

  1. Human Polyclonal MUC1 Primary Antibody for EIA, WB - ABIN951233 : Behrens, Grandgenett, Bailey, Singh, Yi, Yu, Hollingsworth: The reactive tumor microenvironment: MUC1 signaling directly reprograms transcription of CTGF. in Oncogene 2010 (PubMed)
    Show all 3 references for 951233

  2. Human Polyclonal MUC1 Primary Antibody for IF (p), IHC (p) - ABIN687367 : Taki, Ohmuraya, Tanji, Komatsu, Hashimoto, Semba, Araki, Kawaguchi, Baba, Furukawa: GNAS(R201H) and Kras(G12D) cooperate to promote murine pancreatic tumorigenesis recapitulating human intraductal papillary mucinous neoplasm. in Oncogene 2016 (PubMed)

  3. Human Polyclonal MUC1 Primary Antibody for IF (p), IHC (p) - ABIN673824 : Zong, Wu, Wang, Ju, Yan: Chemiluminescence imaging immunoassay of multiple tumor markers for cancer screening. in Analytical chemistry 2012 (PubMed)

  4. Human Polyclonal MUC1 Primary Antibody for IF, IHC - ABIN1533625 : Yu, Yang, Shew, Hong, Yang, Lee, Lee, Luh, Wu: Mucin mRNA expression in lung adenocarcinoma cell lines and tissues. in Oncology 1996 (PubMed)

  5. Human Monoclonal MUC1 Primary Antibody for IHC (p) - ABIN371859 : Margarit, Taylor, Roberts, Hopkins, Davies, Brenton, Conlan, Bunkheila, Joels, White, Gonzalez: MUC1 as a discriminator between endometrium from fertile and infertile patients with PCOS and endometriosis. in The Journal of clinical endocrinology and metabolism 2010 (PubMed)

  6. Cow (Bovine) Polyclonal MUC1 Primary Antibody for IHC, WB - ABIN2776818 : Creaney, Segal, Sterrett, Platten, Baker, Murch, Nowak, Robinson, Millward: Overexpression and altered glycosylation of MUC1 in malignant mesothelioma. in British journal of cancer 2008 (PubMed)

More Antibodies against MUC1 Interaction Partners

Human Mucin 1, Cell Surface Associated (MUC1) interaction partners

  1. Studied and analyzed MUC1 in specimens from patients with cholangiocarcinoma and pancreatic ductal adenocarcinoma. Using lectin microarray analysis, analyzed and found different glycoforms of MUC1 could distinguish between different cancers and degree of malignancy.

  2. These findings uncover a previously unrecognized role for MUC1-C in driving BMI1 (show BMI1 Antibodies) expression and in directly interacting with this stem cell factor (show KITLG Antibodies), linking MUC1-C with function of the PRC1 (show PRC1 Antibodies) in epigenetic gene silencing.

  3. our data suggest a novel molecular mechanism by which tMUC1 may modulate NRP1 (show NELL1 Antibodies)-dependent VEGFR (show KDR Antibodies) signaling in PDA cells.

  4. Results suggest that MUC1 serves as a metabolic regulator in triple-negative breast cancer, facilitating the metabolic reprogramming of glutamine (show GFPT1 Antibodies) utilization that influences triple-negative breast cancer tumor growth.

  5. MUC1-C is of functional importance to induction of DNMT1 (show DNMT1 Antibodies) and DNMT3b (show DNMT3B Antibodies) and, in turn, changes in DNA methylation (show HELLS Antibodies) patterns in cancer cells.

  6. The MUC1 oncoprotein was identified as the critical driver of (extracellular vesicle) EV-mediated myeloid-derived suppressor cells expansion in AML (show RUNX1 Antibodies). microRNA miR34a acts as the regulatory mechanism by which MUC1 drives c-myc (show MYC Antibodies) expression in AML (show RUNX1 Antibodies) cells and EVs.

  7. immunoexpression of different epitopes (external and cytoplasmic) of MUC1 expression are altered in tubes with ectopic pregnancy compared with normal tubes, suggesting an association to explain its etiology

  8. Data show that triple-negative breast cancer (TNBC) patients with pre-therapeutic serum high levels of both carcinoembryonic antigen (CEA (show CEACAM5 Antibodies)) and cancer antigen 15-3 (CA15-3) had shorter overall survival (OS) and disease-free survival (DFS (show FST Antibodies)) rates than those in the low-level groups.

  9. MUC1 expression correlates with tumor metastatic recurrence in postoperative esophageal squamous cell cancer patients

  10. Differences in the apparent expression levels of CEA (show CEACAM5 Antibodies), CA153 and CA125 (show MUC16 Antibodies) in patients with nipple discharge and healthy persons were validated.

Pig (Porcine) Mucin 1, Cell Surface Associated (MUC1) interaction partners

  1. The results indicate that Muc1 gene is significantly associated with litter size in pigs.

  2. The epiblast expressed epithelial markers, MUC1 and E-CADHERIN (show CDH1 Antibodies), and the pluripotency markers, DNMT3B (show DNMT3B Antibodies) and CRIPTO (show TDGF1 Antibodies).

Cow (Bovine) Mucin 1, Cell Surface Associated (MUC1) interaction partners

  1. Endometrial expressions of MUC1 and cytokine genes differed among normal, fertile versus diseased, and subfertile dairy cows.

  2. Bovine Muc1 prevents binding of bacteria to human intestinal cells and may have a role in preventing the binding of common enteropathogenic bacteria to human intestinal epithelial surfaces.

  3. concluded that bovine Muc1 protein is probably an inducible innate immune effector and an important component of the first line of defense against bacterial invasion of epithelial surfaces

Mouse (Murine) Mucin 1, Cell Surface Associated (MUC1) interaction partners

  1. our data suggest a novel molecular mechanism by which tMUC1 may modulate NRP1 (show NRP1 Antibodies)-dependent VEGFR (show KDR Antibodies) signaling in PDA cells.

  2. Low expression of MUC1 is associated with lung carcinogenesis.

  3. Using an extensive collection of novel murine cell lines we have identified distinct roles for Kras and Pten (show PTEN Antibodies) on MUC1 and EMT (show ITK Antibodies) in vivo and in vitro. The data has implications for future design of combination therapies targeting Kras mutations, Pten (show PTEN Antibodies) deletions and MUC1 vaccines.

  4. Gp91phox (show CYBB Antibodies) NADPH oxidase (show NOX1 Antibodies) modulates litter size by up-regulating mucin1 expression in the uterus of mice.

  5. In summary, we have demonstrated that MUC1 on immune cells is a novel regulator of the NLRP3 (show NLRP3 Antibodies) inflammasome, and propose this is mediated by an interaction with signalling components at the cytoplasmic domains of TLRs that involves inhibition of IRAK4 (show IRAK4 Antibodies) activation.

  6. MUC1 regulates IL-1beta (show IL1B Antibodies) secretion induced by the NLRP3 (show NLRP3 Antibodies)-activating bacteria Haemophilus influenzae but not bacteria that activate other inflammasomes.

  7. Muc1 protection during acute kidney injury proceeds by enhancing both the HIF-1 (show HIF1A Antibodies) and beta-catenin (show CTNNB1 Antibodies) protective pathways.

  8. MAMs MUC1 and MUC16 (show MUC16 Antibodies) contribute to the maintenance of immune homeostasis at the ocular surface by limiting TLR-mediated innate immune responses.

  9. the present study provides evidence that Muc1 is a direct target of let-7a and let-7b in mouse uteri during embryo implantation.

  10. Anatomical site-specific Cre-loxP recombination throughout the genital tract of MUC1KrasPten mice leads to MUC1 positive genital tract tumors, and the development of these tumors is influenced by the anatomical environment

MUC1 Antigen Profile

Antigen Summary

This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with MUC1

  • mucin 1, cell surface associated (MUC1) antibody
  • mucin 1, cell surface associated (Muc1) antibody
  • mucin 1, transmembrane (Muc1) antibody
  • CA 15-3 antibody
  • CD227 antibody
  • EMA antibody
  • H23AG antibody
  • KL-6 antibody
  • MAM6 antibody
  • MCKD1 antibody
  • Muc-1 antibody
  • MUC-1/SEC antibody
  • MUC-1/X antibody
  • MUC1/ZD antibody
  • PEM antibody
  • PEMT antibody
  • PUM antibody

Protein level used designations for MUC1

DF3 antigen , H23 antigen , breast carcinoma-associated antigen DF3 , cancer antigen 15-3 , carcinoma-associated mucin , episialin , krebs von den Lungen-6 , mucin 1, transmembrane , mucin-1 , peanut-reactive urinary mucin , polymorphic epithelial mucin , tumor associated epithelial mucin , tumor-associated epithelial membrane antigen , tumor-associated mucin , endometrial mucin-1 , epithelial mucin , MUC-1 , Mucin1

GENE ID SPECIES
4582 Homo sapiens
448784 Canis lupus familiaris
397382 Sus scrofa
281333 Bos taurus
100009240 Oryctolagus cuniculus
24571 Rattus norvegicus
100733534 Cavia porcellus
17829 Mus musculus
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