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MUC1 antibody

MUC1 Reactivity: Human IHC, StM Host: Mouse Monoclonal MUC1-520 unconjugated
Catalog No. ABIN6940099
$575.85
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  • Target See all MUC1 Antibodies
    MUC1 (Mucin 1 (MUC1))
    Reactivity
    • 294
    • 65
    • 31
    • 12
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 203
    • 102
    • 3
    • 1
    • 1
    Mouse
    Clonality
    • 189
    • 118
    • 3
    Monoclonal
    Conjugate
    • 147
    • 27
    • 17
    • 11
    • 11
    • 10
    • 9
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This MUC1 antibody is un-conjugated
    Application
    • 145
    • 116
    • 106
    • 94
    • 86
    • 47
    • 32
    • 31
    • 21
    • 20
    • 20
    • 17
    • 14
    • 13
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Specificity
    In Western blotting, it recognizes proteins in MW range of 265-400 kDa, identified as different glycoforms of EMA. EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack. In immunohistochemical assays, it superbly stains routine formalin/paraffin carcinomas. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.
    Purification
    Purified by Protein A/G
    Immunogen
    Human milk-fat globule membranes (HMFGM)
    Clone
    MUC1-520
    Isotype
    IgG2a kappa
  • Application Notes

    Positive Control: MCF-7 or MDA-231 cells. Breast, colon, ovarian, endometrial carcinoma.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Expiry Date
    24 months
  • Target
    MUC1 (Mucin 1 (MUC1))
    Alternative Name
    MUC1 (MUC1 Products)
    Synonyms
    CA 15-3 antibody, CD227 antibody, EMA antibody, H23AG antibody, KL-6 antibody, MAM6 antibody, MCKD1 antibody, MUC-1 antibody, MUC-1/SEC antibody, MUC-1/X antibody, MUC1/ZD antibody, PEM antibody, PEMT antibody, PUM antibody, Muc-1 antibody, mucin 1, cell surface associated antibody, mucin 1, transmembrane antibody, MUC1 antibody, Muc1 antibody
    Molecular Weight
    265-400kDa
    Gene ID
    4582
    UniProt
    P15941
    Pathways
    Negative Regulation of intrinsic apoptotic Signaling
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