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Browse our NGFB Proteins (NGFB)

Full name:
Nerve Growth Factor beta Proteins (NGFB)
On are 69 Nerve Growth Factor beta (NGFB) Proteins from 16 different suppliers available. Additionally we are shipping NGFB Antibodies (183) and NGFB Kits (53) and many more products for this protein. A total of 312 NGFB products are currently listed.
beta-NGF, HSAN5, Ngfb, ns:zft386, xx:zft386, zgc:109730
list all proteins Gene Name GeneID UniProt
NGFB 18049 P01139
NGFB 4803 P01138
NGFB 310738 P25427

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NGFB Proteins (NGFB) by Origin

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Top referenced NGFB Proteins

  1. Human NGFB Protein expressed in CHO Cells - ABIN2003789 : Ullrich, Gray, Berman, Dull: Human beta-nerve growth factor gene sequence highly homologous to that of mouse. in Nature 1983 (PubMed)
    Show all 6 references for ABIN2003789

  2. Mouse (Murine) NGFB Protein expressed in Escherichia coli (E. coli) - ABIN2667380 : Bradshaw, Blundell, Lapatto, McDonald, Murray-Rust: Nerve growth factor revisited. in Trends in biochemical sciences 1993 (PubMed)
    Show all 4 references for ABIN2667380

  3. Mouse (Murine) NGFB Protein expressed in CHO Cells - ABIN2007732 : Tsui-Pierchala, Ginty: Characterization of an NGF-P-TrkA retrograde-signaling complex and age-dependent regulation of TrkA phosphorylation in sympathetic neurons. in The Journal of neuroscience : the official journal of the Society for Neuroscience 1999 (PubMed)
    Show all 4 references for ABIN2007732

  4. Human NGFB Protein expressed in Escherichia coli (E. coli) - ABIN2667381 : Levi, Alemà: The mechanism of action of nerve growth factor. in Annual review of pharmacology and toxicology 1991 (PubMed)
    Show all 3 references for ABIN2667381

  5. Human NGFB Protein expressed in Escherichia coli (E. coli) - ABIN1096128 : Forsell, Almqvist, Hillertz, Akerud, Otrocka, Eisele, Sun, Andersson, Trivedi, Wollberg, Dekker, Rottici, Sandberg: The use of TrkA-PathHunter assay in high-throughput screening to identify compounds that affect nerve growth factor signaling. in Journal of biomolecular screening 2013 (PubMed)

More Proteins for NGFB Interaction Partners

Mouse (Murine) Nerve Growth Factor beta (NGFB) interaction partners

  1. results suggest that perivascular nerves innervate neovessels as neovasculatures mature and that NGF accelerates the innervation of perivascular nerves in neovessels.

  2. These findings reveal a non-neuronal role for neurotrophins and identify a new regulatory pathway in insulin (show INS Proteins) secretion that can be targeted to ameliorate beta cell dysfunction.

  3. NGF signalling directly controls basal APP (show APP Proteins) phosphorylation, subcellular localization and BACE (show BACE Proteins) cleavage.

  4. NGF facilitates OVA with lowLPS-induced maturation of mouse BMDCs through LPS-up-regulated p75 NTR via activation of NF-kappaB pathways, providing another mechanism for the involvement of NGF in the Th2 response

  5. NGF-OE mice exhibit age-dependent increases in Substance P (show TAC1 Proteins) and CGRP (show CALCA Proteins) in the urothelium and hyperinnervation of the bladder.

  6. TNF-alpha upregulated Nerve Growth Factor [NGF] expression in synovial fibroblasts and macrophages and IL-1beta upregulated NGF expression in synovial fibroblasts. IL-1beta and TNF-alpha may regulate NGF signaling in Osteoarthritic joints and be suitable therapeutic targets for treating Osteoarthritis pain

  7. functional PAP (show ASAP1 Proteins)(thorn) neurons are essential for the analgesic effect, which is mediated by NGF-trkA (show NTRK1 Proteins) signaling.

  8. NGF negatively regulates growth cone retrograde actin flow on laminin.

  9. In E-Reeler (show RELN Proteins) retinas, NGF was significantly increased in retinal ganglion cells and glial cells. E-Reeler (show RELN Proteins) retinal bipolar cells and RGCs overexpress NGF and p75(NTR (show NGFR Proteins)) as a protective endogenous response to Reelin (show RELN Proteins) deprivation.

  10. The NGF-induced up-regulation of TRPV1 (show TRPV1 Proteins) via the increased synthesis and release of endogenous CGRP (show CALCA Proteins) leads to improved cardiac performance in I/R-injured diabetic heart.

Human Nerve Growth Factor beta (NGFB) interaction partners

  1. NGF attenuates these responses-both in vivo and in vitro. Therefore, NGF therapy may represent a novel approach for the management of diabetic keratopathy.

  2. NGF signaling pathway provides a potential target for developing molecularly targeted therapies

  3. these data suggest a positive feedback loop through which NGF-mediated upregulation of p75(NTR (show NGFR Proteins)) can contribute to the chemo-resistance of Triple negative breast cancer cells.

  4. Based on these current developments, the present review provides not only a broad overview of the biological effects of NGF-TrkA-p75NTR on cancer cells and their microenvironment, but also explains why NGF and its receptors are going to evoke major interest as promising therapeutic anti-cancer targets in the coming decade.

  5. NGF/CD133 might be an effective and potent therapeutic target for pancreatic cancer metastasis, particularly in perineural invasion

  6. The analysis of covariance (ANCOVA) indicated that the mean serum GDNF and NTF3 levels of ADHD patients were significantly higher than that of controls. However, serum BDNF and NGF levels did not show any significant differences between groups.

  7. All patients had serum neurotrophin (NT-3, BDNF, NGF) concentrations determined.

  8. Serum NGF does not differentiate between recurrent acute pancreatitis and chronic pancreatitis.

  9. NGF FLIPs TrkA (show NTRK1 Proteins) onto the death TRAIL in neuroblastoma (show ARHGEF16 Proteins) cells

  10. Major depression patients had similar serum NGF to controls.

NGFB Protein Profile

Protein Summary

This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis.

Alternative names and synonyms associated with NGFB

  • nerve growth factor (beta polypeptide) (NGF)
  • nerve growth factor (beta polypeptide) (ngf)
  • beta-Nerve growth factor (FPV072)
  • beta-Nerve growth factor (FPV076)
  • nerve growth factor (Ngf)
  • nerve growth factor (beta polypeptide) (Ngf)
  • beta-NGF protein
  • HSAN5 protein
  • Ngfb protein
  • ns:zft386 protein
  • xx:zft386 protein
  • zgc:109730 protein

Protein level used designations for NGFB

beta-nerve growth factor , nerve growth factor beta , nerve growth factor, beta polypeptide , nerve growth factor , zNGF , beta-Nerve growth factor , nerve growth factor beta subunit , beta-NGF , nerve growth factor, beta , nerve growth factor, beta subunit , Beta-nerve growth factor , nerve growth factor B , beta-beta-nerve growth factor

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1486620 Fowlpox virus
1486624 Fowlpox virus
100144611 Felis catus
100170161 Xenopus (Silurana) tropicalis
18049 Mus musculus
4803 Homo sapiens
310738 Rattus norvegicus
281350 Bos taurus
100733367 Cavia porcellus
407605 Sus scrofa
396466 Gallus gallus
469423 Pan troglodytes
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