Browse our NGFB Proteins (NGFB)

Full name:
Nerve Growth Factor beta Proteins (NGFB)
On are 89 Nerve Growth Factor beta (NGFB) Proteins from 18 different suppliers available. Additionally we are shipping NGFB Antibodies (209) and NGFB Kits (61) and many more products for this protein. A total of 368 NGFB products are currently listed.
beta-NGF, HSAN5, Ngfb, ns:zft386, xx:zft386, zgc:109730
list all proteins Gene Name GeneID UniProt
NGFB 18049 P01139
NGFB 4803 P01138
NGFB 310738 P25427

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NGFB Proteins (NGFB) by Origin

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Top referenced NGFB Proteins

  1. Human NGFB Protein expressed in CHO Cells - ABIN2003789 : Ullrich, Gray, Berman, Dull: Human beta-nerve growth factor gene sequence highly homologous to that of mouse. in Nature 1983 (PubMed)
    Show all 6 references for 2003789

  2. Mouse (Murine) NGFB Protein expressed in CHO Cells - ABIN2007732 : Tsui-Pierchala, Ginty: Characterization of an NGF-P-TrkA retrograde-signaling complex and age-dependent regulation of TrkA phosphorylation in sympathetic neurons. in The Journal of neuroscience : the official journal of the Society for Neuroscience 1999 (PubMed)
    Show all 4 references for 2007732

  3. Mouse (Murine) NGFB Protein expressed in Mouse - ABIN804474 : Varon, Raiborn: Dissociation, fractionation and culture of chick embryo sympathetic ganglionic cells. in Journal of neurocytology 1996 (PubMed)

  4. Human NGFB Protein expressed in Escherichia coli (E. coli) - ABIN1096128 : Forsell, Almqvist, Hillertz, Akerud, Otrocka, Eisele, Sun, Andersson, Trivedi, Wollberg, Dekker, Rottici, Sandberg: The use of TrkA-PathHunter assay in high-throughput screening to identify compounds that affect nerve growth factor signaling. in Journal of biomolecular screening 2013 (PubMed)

More Proteins for NGFB Interaction Partners

Mouse (Murine) Nerve Growth Factor beta (NGFB) interaction partners

  1. results suggest that perivascular nerves innervate neovessels as neovasculatures mature and that NGF accelerates the innervation of perivascular nerves in neovessels.

  2. These findings reveal a non-neuronal role for neurotrophins and identify a new regulatory pathway in insulin (show INS Proteins) secretion that can be targeted to ameliorate beta cell dysfunction.

  3. NGF signalling directly controls basal APP (show APP Proteins) phosphorylation, subcellular localization and BACE (show BACE Proteins) cleavage.

  4. NGF facilitates OVA with lowLPS-induced maturation of mouse BMDCs through LPS-up-regulated p75 NTR via activation of NF-kappaB pathways, providing another mechanism for the involvement of NGF in the Th2 response

  5. NGF-OE mice exhibit age-dependent increases in Substance P (show TAC1 Proteins) and CGRP (show CALCA Proteins) in the urothelium and hyperinnervation of the bladder.

  6. TNF-alpha upregulated Nerve Growth Factor [NGF] expression in synovial fibroblasts and macrophages and IL-1beta upregulated NGF expression in synovial fibroblasts. IL-1beta and TNF-alpha may regulate NGF signaling in Osteoarthritic joints and be suitable therapeutic targets for treating Osteoarthritis pain

  7. functional PAP (show ASAP1 Proteins)(thorn) neurons are essential for the analgesic effect, which is mediated by NGF-trkA (show NTRK1 Proteins) signaling.

  8. NGF negatively regulates growth cone retrograde actin flow on laminin.

  9. In E-Reeler (show RELN Proteins) retinas, NGF was significantly increased in retinal ganglion cells and glial cells. E-Reeler (show RELN Proteins) retinal bipolar cells and RGCs overexpress NGF and p75(NTR (show NGFR Proteins)) as a protective endogenous response to Reelin (show RELN Proteins) deprivation.

  10. The NGF-induced up-regulation of TRPV1 (show TRPV1 Proteins) via the increased synthesis and release of endogenous CGRP (show CALCA Proteins) leads to improved cardiac performance in I/R-injured diabetic heart.

Human Nerve Growth Factor beta (NGFB) interaction partners

  1. The results of this study suggest that proNGF protein levels may augment the diagnostic accuracy of currently used CSF (show CSF2 Proteins) biomarker panels.

  2. Neuroimmune-endocrine events may lead to overactivity of sympathetic nervous system that triggers cascade of pathologic conditions in ovary in polycystic ovary syndrome (PCOS). Data suggest women with PCOS exhibit reduction of CRH (show CRH Proteins) and NGF; reduction of CRH (show CRH Proteins)/NGF may be under influence of sympathetic nervous system and may reflect deficit of neuronal stress-adaptation in PCOS patients. (CRH (show CRH Proteins) = corticotropin releasing hormone (show CRH Proteins))

  3. The rare nerve growth factor-beta (NGFB) mutation R221W causes a selective loss of thinly myelinated fibers and especially unmyelinated C-fibers. Carriers of this mutation show altered pain sensation.

  4. NGF expression was positively correlated with disease severity and visceral hypersensitivity in irritable bowel syndrome patients.

  5. a stage-related modulation of beta-NGF and its receptors in the inflammatory process of OA

  6. BDNF and NGF serum levels are reduced in the early and moderate glaucoma stages, suggesting the possibility that both factors could be further investigated as potential circulating biomarkers for the early detection of glaucoma.

  7. overexpression of ARMS blocked NGF-mediated secretion, without affecting basal secretion, a decrease in ARMS resulted in potentiation. Similar effects were observed with synembryn-B, a protein that interacts directly with ARMS. Downstream of ARMS and synembryn-B are Galphaq and Trio proteins, which modulate the activity of Rac1 in response to NGF

  8. Data show that the standardized nerve growth factor (NGF) concentration was negatively correlated with continuous pain, neuropathic pain and total score, and the standardized S100 proteins S100A8 (show S100A8 Proteins)/A9 concentration was positively correlated with present pain intensity and continuous pain.

  9. Results indicate that NGF inhibited CRT (show SLC6A8 Proteins) translocation induced by mitoxantrone. NGF effect on CRT (show SLC6A8 Proteins) translocation could have consequences in immunotherapy, potentially lessening the effectiveness of this type of treatment.

  10. NGF stimulates generation of neurons, but not neuronal progenitors from embryonic stem cells and affects the proportion of specific types of neurons in cultures of differentiating embryonic stem cells.

NGFB Protein Profile

Protein Summary

This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis.

Alternative names and synonyms associated with NGFB

  • nerve growth factor (beta polypeptide) (NGF)
  • nerve growth factor (beta polypeptide) (ngf)
  • beta-Nerve growth factor (FPV072)
  • beta-Nerve growth factor (FPV076)
  • nerve growth factor (Ngf)
  • nerve growth factor (beta polypeptide) (Ngf)
  • beta-NGF protein
  • HSAN5 protein
  • Ngfb protein
  • ns:zft386 protein
  • xx:zft386 protein
  • zgc:109730 protein

Protein level used designations for NGFB

beta-nerve growth factor , nerve growth factor beta , nerve growth factor, beta polypeptide , nerve growth factor , zNGF , beta-Nerve growth factor , nerve growth factor beta subunit , beta-NGF , nerve growth factor, beta , nerve growth factor, beta subunit , Beta-nerve growth factor , nerve growth factor B , beta-beta-nerve growth factor

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310738 Rattus norvegicus
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407605 Sus scrofa
396466 Gallus gallus
469423 Pan troglodytes
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