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Nicastrin Proteins

(Nicastrin (NCSTN))
This gene encodes a Type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex. The encoded protein cleaves integral membrane proteins, including Notch receptors and beta-amyloid precursor protein, and may be a stabilizing cofactor required for gamma-secretase complex assembly. The cleavage of beta-amyloid precursor protein yields amyloid beta peptide, the main component of the neuritic plaque and the hallmark lesion in the brains of patients with Alzheimer's disease\; however, the nature of the encoded protein's role in Alzheimer's disease is not known for certain. Alternatively spliced transcript variants have been described, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008].
Nicastrin Protein (NCSTN) (AA 1-689) (GST tag) Nicastrin Protein (NCSTN) (AA 1-689) (GST tag) Nicastrin Protein (NCSTN) (AA 1-689) (GST tag) (ABIN1312150)

NCSTN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

Nicastrin Protein (NCSTN) (AA 16-115) (GST tag) Nicastrin Protein (NCSTN) (AA 16-115) (GST tag) Nicastrin Protein (NCSTN) (AA 16-115) (GST tag) (ABIN1312152)

NCSTN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

Nicastrin Protein (NCSTN) (His tag) Nicastrin Protein (NCSTN) (His tag) Nicastrin Protein (NCSTN) (His tag) (ABIN7320108)

NCSTN Origin: Mouse Host: HEK-293 Cells Recombinant > 99 % as determined by SDS-PAGE

Nicastrin Proteins by Origin

Find Nicastrin Proteins for a variety of species such as anti-Human Nicastrin, anti-Mouse Nicastrin, anti-Rat Nicastrin. The species listed below are among those available. Click on a link to go to the corresponding products.

Nicastrin Proteins by Source

Here you will find Nicastrin Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Nicastrin Proteins by Protein Type

Here you can find Nicastrin Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Nicastrin Proteins by Application

Find Nicastrin Proteins validated for a specific application such as WB, ELISA, AP, AA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Nicastrin Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312150
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312152
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7320108
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7320109
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7405702
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7417279
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7197196
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2727295
Quantity 20 μg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1613731
Quantity 1 mg
Datasheet Datasheet

Aliases for Nicastrin Proteins

nicastrin (NCSTN) Proteins
nicastrin (nct) Proteins
nicastrin (ncstn) Proteins
nicastrin (CpipJ_CPIJ001617) Proteins
nicastrin (Ncstn) Proteins
Nicastrin (aph-2) Proteins
9430068N19Rik Proteins
AA727311 Proteins
agro Proteins
APH2 Proteins
Aph2 Proteins
CG7012 Proteins
D1Dau13e Proteins
DKFZp469O2418 Proteins
Dmel\\CG7012 Proteins
dNct Proteins
Kiaa0253 Proteins
mKIAA0253 Proteins
NCSTN Proteins
Nct Proteins
Nic Proteins
nic Proteins
S5A Proteins
ST96B Proteins
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