Browse our anti-TNFSF11 (TNFSF11) Antibodies

Full name:
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 Antibodies (TNFSF11)
On www.antibodies-online.com are 257 Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) Antibodies from 32 different suppliers available. Additionally we are shipping TNFSF11 Kits (104) and TNFSF11 Proteins (56) and many more products for this protein. A total of 434 TNFSF11 products are currently listed.
Synonyms:
BTF3L1, CD254, hRANKL2, HUMBTFB, Ly109l, OCIF, ODF, Opg, OPGL, OPTB2, RANKL, sOdf, TNFRSF11B, TNFSF11, Trance
list all antibodies Gene Name GeneID UniProt
TNFSF11 690  
TNFSF11 21943 O35235
TNFSF11 117516 Q9ESE2

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anti-Human TNFSF11 Antibodies:

anti-Mouse (Murine) TNFSF11 Antibodies:

anti-Rat (Rattus) TNFSF11 Antibodies:

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Top referenced anti-TNFSF11 Antibodies

  1. Human Monoclonal TNFSF11 Primary Antibody for ChIP, FACS - ABIN252476 : Kikuchi, Matsuguchi, Tsuboi, Mitani, Tanaka, Matsuoka, Yamamoto, Hishikawa, Noguchi, Yoshikai: Gene expression of osteoclast differentiation factor is induced by lipopolysaccharide in mouse osteoblasts via Toll-like receptors. in Journal of immunology (Baltimore, Md. : 1950) 2001 (PubMed)
    Show all 19 references for 252476

  2. Human Polyclonal TNFSF11 Primary Antibody for IF (p), IHC (p) - ABIN672696 : Yang, Li, Yang, Shen, Zou, Zhu, Zhang, Yang, Li: Efficacy and safety of echinacoside in a rat osteopenia model. in Evidence-based complementary and alternative medicine : eCAM 2013 (PubMed)
    Show all 12 references for 672696

  3. Human Monoclonal TNFSF11 Primary Antibody for ChIP, CyTOF - ABIN252546 : Hsu, Lacey, Dunstan, Solovyev, Colombero, Timms, Tan, Elliott, Kelley, Sarosi, Wang, Xia, Elliott, Chiu, Black, Scully, Capparelli, Morony, Shimamoto, Bass, Boyle: Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand. in Proceedings of the National Academy of Sciences of the United States of America 1999 (PubMed)
    Show all 10 references for 252546

  4. Human Polyclonal TNFSF11 Primary Antibody for IF (p), IHC (p) - ABIN668556 : Zhang, Liu, Li, Bai: Mycobacterium tuberculosis 10-kDa co-chaperonin regulates the expression levels of receptor activator of nuclear factor-?B ligand and osteoprotegerin in human osteoblasts. in Experimental and therapeutic medicine 2015 (PubMed)
    Show all 9 references for 668556

  5. Human Monoclonal TNFSF11 Primary Antibody for FACS, IHC (fro) - ABIN252684 : Yoneda, Ishimaru, Arakaki, Kobayashi, Izawa, Moriyama, Hayashi: Estrogen deficiency accelerates murine autoimmune arthritis associated with receptor activator of nuclear factor-kappa B ligand-mediated osteoclastogenesis. in Endocrinology 2004 (PubMed)
    Show all 3 references for 252684

  6. Human Polyclonal TNFSF11 Primary Antibody for IF, ELISA - ABIN1533487 : Anderson, Maraskovsky, Billingsley, Dougall, Tometsko, Roux, Teepe, DuBose, Cosman, Galibert: A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. in Nature 1997 (PubMed)
    Show all 2 references for 1533487

  7. Human Polyclonal TNFSF11 Primary Antibody for EIA, Func - ABIN116281 : Grimaud, Soubigou, Couillaud, Coipeau, Moreau, Passuti, Gouin, Redini, Heymann: Receptor activator of nuclear factor kappaB ligand (RANKL)/osteoprotegerin (OPG) ratio is increased in severe osteolysis. in The American journal of pathology 2003 (PubMed)

  8. Human Monoclonal TNFSF11 Primary Antibody for WB - ABIN2668631 : Hikita, Yana, Wakeyama, Nakamura, Kadono, Oshima, Nakamura, Seiki, Tanaka: Negative regulation of osteoclastogenesis by ectodomain shedding of receptor activator of NF-kappaB ligand. in The Journal of biological chemistry 2006 (PubMed)

More Antibodies against TNFSF11 Interaction Partners

Human Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) interaction partners

  1. RANK/RANKL signaling is involved in the androgen deprivation therapy-induced acceleration of bone metastasis in castration-insensitive prostate cancer and is inhibited by osteoprotegerin (show TNFRSF11B Antibodies) to prevent bone metastasis.

  2. This study suggested that RANKL could be a marker to differentiate between pagetoid squamous cell carcinoma in situ and extramammary Paget disease .

  3. TNF-alpha-converting enzyme (show ADAM17 Antibodies) -mediated cleavage of soluble RANKL from activated lymphocytes, especially B cells, can promote osteoclastogenesis in periodontitis.

  4. RANKL is required for progesterone-mediated cell proliferation in BRCA1mut/+ breast tissue.

  5. MAOA (show MAOA Antibodies) provides tumor cell growth advantages in the bone microenvironment by stimulating interleukin-6 (IL6 (show IL6 Antibodies)) release from osteoblasts, and triggers skeletal colonization by activating osteoclastogenesis through osteoblast production of RANKL and IL6 (show IL6 Antibodies).

  6. In this review, we will provide a summary of the biological functions of RANK signaling pathway (receptor activator of nuclear factor kappaB ligand RANKL and its receptor RANK ) and downstream pathways in bone remodeling, immunity and epithelial homeostasis, with a particular emphasis on cancer

  7. The results showed that AG490 inhibited (p)-JAK2 (show JAK2 Antibodies) and RANKL expression.

  8. Review: OPG (show TNFRSF11B Antibodies), RANKL and TRAIL are involved in vascular calcification.

  9. Our results suggest that the polymorphism of the RANKL, RANK, and OPG (show TNFRSF11B Antibodies) genes does not make a significant genetic contribution to heel ultrasound measurements in a population of young Caucasian adults. Further studies replicating the results in independent populations are needed to support these initial findings.

  10. OPG (show TNFRSF11B Antibodies) rs2073618, RANK rs75404003, and RANKL rs9594782 single nucleotide poymorphisms may predispose LVH in thalassemia patients.

Mouse (Murine) Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) interaction partners

  1. This study showed that RANKL favors osteoclastogenesis via attenuation of Nrf2 (show NFE2L2 Antibodies)-mediated antioxidant enzyme expression by competing with Bach1 (show BACH1 Antibodies) nuclear accumulation.

  2. Membrane-bound RANKL induces M cell differentiation and CCL20 (show CCL20 Antibodies) expression in the follicle associated epithelium of gut (show GUSB Antibodies)-associated lymphoid tissues.

  3. The data show that S. aureus enhances bone resorption and periosteal osteoclast formation by increasing osteoblast RANKL production through TLR2 (show TLR2 Antibodies).

  4. Data (including data from studies using knockout mice) suggest that RANKL enhances TNF (show TNF Antibodies)-induced osteoclast formation from precursor spleen cells and enhances bone resorption independently of Traf6 (show TRAF6 Antibodies) by degrading Traf3 (show TRAF3 Antibodies), a known inhibitor of osteoclastogenesis. (RANKL = osteoclast differentiation factor; TNF (show TNF Antibodies) = tumor necrosis factor (show TNF Antibodies); Traf (show TRAF1 Antibodies) = TNF (show TNF Antibodies) receptor-associated factor)

  5. Results suggest that MAPK (show MAPK1 Antibodies) signaling pathway is necessary for receptor activator of nuclear factor kappa-B ligand (RANKL) expression in bone marrow stromal cell.

  6. endocortical resorption is driven by reduced osteoprotegerin (show TNFRSF11B Antibodies) rather than elevated RANKL expression

  7. The results showed that AG490 inhibited (p)-JAK2 (show JAK2 Antibodies) and RANKL expression.

  8. Play a supportive role in the RANKL-dependent differentiation.

  9. increased expression of RANKL in heterogeneous bone marrow cells provoked bone destruction during Group A Streptococcus infection.

  10. beta-lapachone inhibits RANKL-induced osteoclastogenesis and could be considered a potent inhibitor of RANKL-mediated bone diseases

TNFSF11 Antigen Profile

Antigen Summary

This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced transcript variants have been found.

Alternative names and synonyms associated with TNFSF11

  • tumor necrosis factor (ligand) superfamily, member 11 (TNFSF11) antibody
  • basic transcription factor 3 pseudogene 11 (BTF3P11) antibody
  • tumor necrosis factor (ligand) superfamily, member 11 (Tnfsf11) antibody
  • tumor necrosis factor receptor superfamily, member 11b (Tnfrsf11b) antibody
  • tumor necrosis factor receptor superfamily, member 11b (TNFRSF11B) antibody
  • BTF3L1 antibody
  • CD254 antibody
  • hRANKL2 antibody
  • HUMBTFB antibody
  • Ly109l antibody
  • OCIF antibody
  • ODF antibody
  • Opg antibody
  • OPGL antibody
  • OPTB2 antibody
  • RANKL antibody
  • sOdf antibody
  • TNFRSF11B antibody
  • TNFSF11 antibody
  • Trance antibody

Protein level used designations for TNFSF11

tumor necrosis factor (ligand) superfamily, member 11 , tumor necrosis factor ligand superfamily member 11 , Receptor activator of nuclear factor kappa-B ligand , TNF-related activation-induced cytokine , osteoclast differentiation factor , osteoprotegerin ligand , receptor activator of nuclear factor kappa B ligand , receptor activator of nuclear factor kappa-B ligand , OPG ligand , receptor activator of NF-kappaB ligand , tumor necrosis factor-related activation-induced cytokine , ODF , OPGL , TRANCE , Osteoprotegerin , tumor necrosis factor receptor superfamily member 11B , tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)

GENE ID SPECIES
467353 Pan troglodytes
513836 Bos taurus
609418 Canis lupus familiaris
699955 Macaca mulatta
100599838 Nomascus leucogenys
690 Homo sapiens
8600 Homo sapiens
21943 Mus musculus
117516 Rattus norvegicus
25341 Rattus norvegicus
378803 Gallus gallus
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