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Browse our anti-TNFSF11 (TNFSF11) Antibodies

Full name:
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 Antibodies (TNFSF11)
On are 249 Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) Antibodies from 30 different suppliers available. Additionally we are shipping TNFSF11 Kits (91) and TNFSF11 Proteins (54) and many more products for this protein. A total of 407 TNFSF11 products are currently listed.
BTF3L1, CD254, hRANKL2, HUMBTFB, Ly109l, OCIF, ODF, Opg, OPGL, OPTB2, RANKL, sOdf, TNFRSF11B, TNFSF11, Trance
list all antibodies Gene Name GeneID UniProt
TNFSF11 690  
TNFSF11 21943 O35235
TNFSF11 117516 Q9ESE2

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anti-Human TNFSF11 Antibodies:

anti-Mouse (Murine) TNFSF11 Antibodies:

anti-Rat (Rattus) TNFSF11 Antibodies:

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Top referenced anti-TNFSF11 Antibodies

  1. Human Polyclonal TNFSF11 Primary Antibody for IF (p), IHC (p) - ABIN672696 : Yang, Li, Yang, Shen, Zou, Zhu, Zhang, Yang, Li: Efficacy and safety of echinacoside in a rat osteopenia model. in Evidence-based complementary and alternative medicine : eCAM 2013 (PubMed)
    Show all 8 references for ABIN672696

  2. Human Polyclonal TNFSF11 Primary Antibody for IF (p), IHC (p) - ABIN668556 : Zhang, Liu, Li, Bai: Mycobacterium tuberculosis 10-kDa co-chaperonin regulates the expression levels of receptor activator of nuclear factor-?B ligand and osteoprotegerin in human osteoblasts. in Experimental and therapeutic medicine 2015 (PubMed)
    Show all 7 references for ABIN668556

  3. Human Polyclonal TNFSF11 Primary Antibody for EIA, IHC (p) - ABIN500805 : Kong, Yoshida, Sarosi, Tan, Timms, Capparelli, Morony, Oliveira-dos-Santos, Van, Itie, Khoo, Wakeham, Dunstan, Lacey, Mak, Boyle, Penninger: OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. in Nature 1999 (PubMed)
    Show all 4 references for ABIN500805

  4. Human Polyclonal TNFSF11 Primary Antibody for IF, ELISA - ABIN1533487 : Anderson, Maraskovsky, Billingsley, Dougall, Tometsko, Roux, Teepe, DuBose, Cosman, Galibert: A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. in Nature 1997 (PubMed)
    Show all 2 references for ABIN1533487

  5. Human Polyclonal TNFSF11 Primary Antibody for EIA, Func - ABIN116281 : Grimaud, Soubigou, Couillaud, Coipeau, Moreau, Passuti, Gouin, Redini, Heymann: Receptor activator of nuclear factor kappaB ligand (RANKL)/osteoprotegerin (OPG) ratio is increased in severe osteolysis. in The American journal of pathology 2003 (PubMed)

  6. Human Monoclonal TNFSF11 Primary Antibody for WB - ABIN2668631 : Hikita, Yana, Wakeyama, Nakamura, Kadono, Oshima, Nakamura, Seiki, Tanaka: Negative regulation of osteoclastogenesis by ectodomain shedding of receptor activator of NF-kappaB ligand. in The Journal of biological chemistry 2006 (PubMed)

More Antibodies against TNFSF11 Interaction Partners

Human Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) interaction partners

  1. Study identified a novel RANKL function in the promotion of cell adhesion to type I collagen through the RANKL-NF-kappa B (show NFKB1 Antibodies)-integrin alpha 2 (show ITGA2 Antibodies) pathway and found integrin alpha2 and RANKL up-regulated in non small cell lung carcinoma.

  2. OPG (show TNFRSF11B Antibodies) and RANKL polymorphisms were associated with the occurrence of alcohol-induced ONFH.

  3. Results demonstrated that the type of inflammatory infiltrate present in periradicular cysts appears to influence the expression of RANK, RANKL, and osteoprotegerin (show TNFRSF11B Antibodies)

  4. Results showed that the expressions of RANKL and IL-17A (show IL17A Antibodies) were higher in the treatment group than the nontreatment group (P < .05) and higher in males than in females (P < .05). Their increments were well correlated with each other (r = 0.788, P = < .01) but were not time dependent

  5. PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) pathway stimulates the expressions of RANKL, PTHrP (show PTHLH Antibodies), and BMP-2 (show BMP2 Antibodies) partly through NF-kappaB (show NFKB1 Antibodies), suggesting its importance for bone metastasis of prostate carcinoma

  6. This study demonstrates that clodronate decreases the compression-induced RANKL/OPG ratio expressed by human osteoblasts.

  7. High RANKL expression is associated with endometrial metastasis.

  8. OPG (show TNFRSF11B Antibodies) and RANKL may play an integral role in breast cancer cells homing to the bone environment

  9. In conclusion, rheumatoid arthritis synovial fibroblasts were activated by CXCL16 (show CXCL16 Antibodies) to produce RANKL via pathways involving JAK2 (show JAK2 Antibodies)/STAT3 (show STAT3 Antibodies) and p38/MAPK (show MAPK14 Antibodies)

  10. Alendronate stimulated OPG (show TNFRSF11B Antibodies) mRNA and protein expression, but not RANKL expression, in fibroblasts from patients with aseptic loosening following total hip arthroplasty.

Mouse (Murine) Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) interaction partners

  1. Lipopolysaccharides significantly up-regulated RANKL expression and activated the ERK1/2 (show MAPK1/3 Antibodies) pathway to induce IL-6 (show IL6 Antibodies) mRNA expression and protein synthesis in MLO-Y4 cells.

  2. Mechanistically, RL negatively regulates Stat5 (show STAT5A Antibodies) phosphorylation and Elf5 (show ELF5 Antibodies) expression at the onset of lactogenesis. Continuous RL exposure leads to the expansion of basal and bipotent cells in WT and MMTV-RANK acini. Overall, we demonstrate that enhanced Rank signaling impairs secretory differentiation during pregnancy by inhibition of the prolactin (show PRL Antibodies)/p-Stat5 (show STAT5A Antibodies) pathway.

  3. this study shows that OPG constitutes an early biomarker with in experimental model od severe malaria

  4. Osteoprotegerin (show TNFRSF11B Antibodies) plays a role in preserving myocardial structure and function with ageing through a reduction in apoptosis and preservation of the matrix structure

  5. These results indicate that activation of Panx1 (show PANX1 Antibodies) and P2X7 (show P2RX7 Antibodies) R are required for apoptotic osteocytes in fatigued bone to trigger RANKL production in neighboring bystander osteocytes and implicate ATP as an essential signal mediating this process.

  6. These results suggest that GP2(+)Tnfaip2 (show TNFAIP2 Antibodies)(+) cells in NALT are equivalent to intestinal M cells, and that RANKL-RANK signaling induces their differentiation.

  7. These results highlight the role of distal enhancers in the regulation of RANKL expression by PTH (show PTH Antibodies) and perhaps 1,25(OH)2D3 and suggest that the RL-D2 and RL-D5 enhancers contribute in either an additive or synergistic manner to regulate bone remodeling.

  8. NMP4 (show ZNF384 Antibodies) deficiency suppressed the arthritis-induced increase in bone resorption, expression of RANKL and MMP-3 (show MMP3 Antibodies) mRNA.

  9. the results of the present study strongly suggest that mimosine, a normoxic inducer of HIF, inhibits the PGF2ainduced osteoprotegerin (show TNFRSF11B Antibodies) synthesis without affecting the IL-6 (show IL6 Antibodies) synthesis in osteoblasts

  10. Adiponectin (show ADIPOQ Antibodies) exerts novel effects to limit the production and action of mono-MPs, underscoring yet another pleiotropic effect of this adipokine.

TNFSF11 Antigen Profile

Antigen Summary

This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced transcript variants have been found.

Alternative names and synonyms associated with TNFSF11

  • tumor necrosis factor (ligand) superfamily, member 11 (TNFSF11) antibody
  • basic transcription factor 3 pseudogene 11 (BTF3P11) antibody
  • tumor necrosis factor (ligand) superfamily, member 11 (Tnfsf11) antibody
  • tumor necrosis factor receptor superfamily, member 11b (Tnfrsf11b) antibody
  • tumor necrosis factor receptor superfamily, member 11b (TNFRSF11B) antibody
  • BTF3L1 antibody
  • CD254 antibody
  • hRANKL2 antibody
  • HUMBTFB antibody
  • Ly109l antibody
  • OCIF antibody
  • ODF antibody
  • Opg antibody
  • OPGL antibody
  • OPTB2 antibody
  • RANKL antibody
  • sOdf antibody
  • TNFRSF11B antibody
  • TNFSF11 antibody
  • Trance antibody

Protein level used designations for TNFSF11

tumor necrosis factor (ligand) superfamily, member 11 , tumor necrosis factor ligand superfamily member 11 , Receptor activator of nuclear factor kappa-B ligand , TNF-related activation-induced cytokine , osteoclast differentiation factor , osteoprotegerin ligand , receptor activator of nuclear factor kappa B ligand , receptor activator of nuclear factor kappa-B ligand , OPG ligand , receptor activator of NF-kappaB ligand , tumor necrosis factor-related activation-induced cytokine , ODF , OPGL , TRANCE , Osteoprotegerin , tumor necrosis factor receptor superfamily member 11B , tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)

467353 Pan troglodytes
513836 Bos taurus
609418 Canis lupus familiaris
699955 Macaca mulatta
100599838 Nomascus leucogenys
690 Homo sapiens
8600 Homo sapiens
21943 Mus musculus
117516 Rattus norvegicus
25341 Rattus norvegicus
378803 Gallus gallus
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