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Browse our anti-TNFSF11 (TNFSF11) Antibodies

Full name:
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 Antibodies (TNFSF11)
On are 263 Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) Antibodies from 32 different suppliers available. Additionally we are shipping TNFSF11 Kits (102) and TNFSF11 Proteins (54) and many more products for this protein. A total of 432 TNFSF11 products are currently listed.
BTF3L1, CD254, hRANKL2, HUMBTFB, Ly109l, OCIF, ODF, Opg, OPGL, OPTB2, RANKL, sOdf, TNFRSF11B, TNFSF11, Trance
list all antibodies Gene Name GeneID UniProt
TNFSF11 690  
TNFSF11 21943 O35235
TNFSF11 117516 Q9ESE2

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anti-Human TNFSF11 Antibodies:

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Top referenced anti-TNFSF11 Antibodies

  1. Human Monoclonal TNFSF11 Primary Antibody for ChIP, FACS - ABIN252476 : Kikuchi, Matsuguchi, Tsuboi, Mitani, Tanaka, Matsuoka, Yamamoto, Hishikawa, Noguchi, Yoshikai: Gene expression of osteoclast differentiation factor is induced by lipopolysaccharide in mouse osteoblasts via Toll-like receptors. in Journal of immunology (Baltimore, Md. : 1950) 2001 (PubMed)
    Show all 19 references for ABIN252476

  2. Human Monoclonal TNFSF11 Primary Antibody for ChIP, CyTOF - ABIN252546 : Hsu, Lacey, Dunstan, Solovyev, Colombero, Timms, Tan, Elliott, Kelley, Sarosi, Wang, Xia, Elliott, Chiu, Black, Scully, Capparelli, Morony, Shimamoto, Bass, Boyle: Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand. in Proceedings of the National Academy of Sciences of the United States of America 1999 (PubMed)
    Show all 10 references for ABIN252546

  3. Human Polyclonal TNFSF11 Primary Antibody for IF (p), IHC (p) - ABIN672696 : Yang, Li, Yang, Shen, Zou, Zhu, Zhang, Yang, Li: Efficacy and safety of echinacoside in a rat osteopenia model. in Evidence-based complementary and alternative medicine : eCAM 2013 (PubMed)
    Show all 8 references for ABIN672696

  4. Human Polyclonal TNFSF11 Primary Antibody for IF (p), IHC (p) - ABIN668556 : Zhang, Liu, Li, Bai: Mycobacterium tuberculosis 10-kDa co-chaperonin regulates the expression levels of receptor activator of nuclear factor-?B ligand and osteoprotegerin in human osteoblasts. in Experimental and therapeutic medicine 2015 (PubMed)
    Show all 7 references for ABIN668556

  5. Human Polyclonal TNFSF11 Primary Antibody for EIA, IHC (p) - ABIN500805 : Kong, Yoshida, Sarosi, Tan, Timms, Capparelli, Morony, Oliveira-dos-Santos, Van, Itie, Khoo, Wakeham, Dunstan, Lacey, Mak, Boyle, Penninger: OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. in Nature 1999 (PubMed)
    Show all 4 references for ABIN500805

  6. Human Monoclonal TNFSF11 Primary Antibody for FACS, IHC (fro) - ABIN252684 : Yoneda, Ishimaru, Arakaki, Kobayashi, Izawa, Moriyama, Hayashi: Estrogen deficiency accelerates murine autoimmune arthritis associated with receptor activator of nuclear factor-kappa B ligand-mediated osteoclastogenesis. in Endocrinology 2004 (PubMed)
    Show all 3 references for ABIN252684

  7. Human Polyclonal TNFSF11 Primary Antibody for IF, ELISA - ABIN1533487 : Anderson, Maraskovsky, Billingsley, Dougall, Tometsko, Roux, Teepe, DuBose, Cosman, Galibert: A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. in Nature 1997 (PubMed)
    Show all 2 references for ABIN1533487

  8. Human Monoclonal TNFSF11 Primary Antibody for WB - ABIN2668631 : Hikita, Yana, Wakeyama, Nakamura, Kadono, Oshima, Nakamura, Seiki, Tanaka: Negative regulation of osteoclastogenesis by ectodomain shedding of receptor activator of NF-kappaB ligand. in The Journal of biological chemistry 2006 (PubMed)

  9. Human Polyclonal TNFSF11 Primary Antibody for EIA, Func - ABIN116281 : Grimaud, Soubigou, Couillaud, Coipeau, Moreau, Passuti, Gouin, Redini, Heymann: Receptor activator of nuclear factor kappaB ligand (RANKL)/osteoprotegerin (OPG) ratio is increased in severe osteolysis. in The American journal of pathology 2003 (PubMed)

More Antibodies against TNFSF11 Interaction Partners

Human Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) interaction partners

  1. the overexpression of RANKL and high membranous RANKL localization in osteoblasts are related to defective CF transmembrane conductance regulator, and may worsen bone resorption, leading to bone loss in patients with cystic fibrosis (show S100A8 Antibodies).

  2. The expression for RANKL and OPG (show TNFRSF11B Antibodies) and the RANKL/OPG ratio were not significantly different between symptomatic and asymptomatic periapical lesions.

  3. HBOT increased serum OPG (show TNFRSF11B Antibodies) levels but receptor activator of nuclear factor kappa-B ligand (RANKL) levels did not change.

  4. Preterm neonates exposed to Antenatal Glucocorticosteroid have higher serum levels of OPG (show TNFRSF11B Antibodies), while premature neonates not exposed to Antenatal Glucocorticosteroid have serum OPG (show TNFRSF11B Antibodies) and RANKL levels similar to those measured in healthy term neonates.

  5. Twenty-one single-nucleotide polymorphisms (SNPs) of TNFSF11, TNFRSF11A, and TNFRSF11B were genotyped. This study suggests that TNFRSF11B but not TNFSF11 and TNFRSF11A genetic polymorphisms are associated with Type 2 Diabetes Mellitus in Southern Han Chinese women.

  6. the OPG/RANKL/RANK system might be directly influenced by genetic variants of NOTCH1 (show NOTCH1 Antibodies) in aortic valve calcification.

  7. results suggest that serum OPG (show TNFRSF11B Antibodies) and RANKL levels are inversely associated with bone loss in men with advanced stage COPD (show ARCN1 Antibodies).

  8. These data show that the osteoprotegerin (show TNFRSF11B Antibodies) and receptor-activator of nuclear factor-kappaB ligand system is associated with bone markers and bone mineral density at the lumbar spine after obesity surgery.

  9. the functional expression of RANKL in CD4 (show CD4 Antibodies)+/CD8 (show CD8A Antibodies)+ T cells and Th17 cells, and the potential role of these cells in chronic obstructive pulmonary disease-associated bone loss was investigated.

  10. Postmenopausal women with Rheumatoid Arthritis, carrying either the RANKL-290T allele or possessing the RANK 575CC genotype were more likely to develop osteoporosis.

Mouse (Murine) Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) interaction partners

  1. miR (show MLXIP Antibodies)-338-3p may play a significant role in glucocorticoid-induced osteoclast differentiation and function by targeting RANKL in osteoclasts.

  2. the protein and RNA levels of RANKLinduced cFos and nuclear factor of activated T-cell (show NFATC3 Antibodies) cytoplasmic 1 were suppressed by centipedegrass extract (CGE). These results indicated that CGE may serve as a useful drug in the prevention of bone loss.

  3. Lipopolysaccharides significantly up-regulated RANKL expression and activated the ERK1/2 (show MAPK1/3 Antibodies) pathway to induce IL-6 (show IL6 Antibodies) mRNA expression and protein synthesis in MLO-Y4 cells.

  4. Mechanistically, RL negatively regulates Stat5 (show STAT5A Antibodies) phosphorylation and Elf5 (show ELF5 Antibodies) expression at the onset of lactogenesis. Continuous RL exposure leads to the expansion of basal and bipotent cells in WT and MMTV-RANK acini. Overall, we demonstrate that enhanced Rank signaling impairs secretory differentiation during pregnancy by inhibition of the prolactin (show PRL Antibodies)/p-Stat5 (show STAT5A Antibodies) pathway.

  5. this study shows that OPG constitutes an early biomarker with in experimental model od severe malaria

  6. Osteoprotegerin (show TNFRSF11B Antibodies) plays a role in preserving myocardial structure and function with ageing through a reduction in apoptosis and preservation of the matrix structure

  7. These results indicate that activation of Panx1 (show PANX1 Antibodies) and P2X7 (show P2RX7 Antibodies) R are required for apoptotic osteocytes in fatigued bone to trigger RANKL production in neighboring bystander osteocytes and implicate ATP as an essential signal mediating this process.

  8. These results suggest that GP2(+)Tnfaip2 (show TNFAIP2 Antibodies)(+) cells in NALT are equivalent to intestinal M cells, and that RANKL-RANK signaling induces their differentiation.

  9. These results highlight the role of distal enhancers in the regulation of RANKL expression by PTH (show PTH Antibodies) and perhaps 1,25(OH)2D3 and suggest that the RL-D2 and RL-D5 enhancers contribute in either an additive or synergistic manner to regulate bone remodeling.

  10. NMP4 (show ZNF384 Antibodies) deficiency suppressed the arthritis-induced increase in bone resorption, expression of RANKL and MMP-3 (show MMP3 Antibodies) mRNA.

TNFSF11 Antigen Profile

Antigen Summary

This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced transcript variants have been found.

Alternative names and synonyms associated with TNFSF11

  • tumor necrosis factor (ligand) superfamily, member 11 (TNFSF11) antibody
  • basic transcription factor 3 pseudogene 11 (BTF3P11) antibody
  • tumor necrosis factor (ligand) superfamily, member 11 (Tnfsf11) antibody
  • tumor necrosis factor receptor superfamily, member 11b (Tnfrsf11b) antibody
  • tumor necrosis factor receptor superfamily, member 11b (TNFRSF11B) antibody
  • BTF3L1 antibody
  • CD254 antibody
  • hRANKL2 antibody
  • HUMBTFB antibody
  • Ly109l antibody
  • OCIF antibody
  • ODF antibody
  • Opg antibody
  • OPGL antibody
  • OPTB2 antibody
  • RANKL antibody
  • sOdf antibody
  • TNFRSF11B antibody
  • TNFSF11 antibody
  • Trance antibody

Protein level used designations for TNFSF11

tumor necrosis factor (ligand) superfamily, member 11 , tumor necrosis factor ligand superfamily member 11 , Receptor activator of nuclear factor kappa-B ligand , TNF-related activation-induced cytokine , osteoclast differentiation factor , osteoprotegerin ligand , receptor activator of nuclear factor kappa B ligand , receptor activator of nuclear factor kappa-B ligand , OPG ligand , receptor activator of NF-kappaB ligand , tumor necrosis factor-related activation-induced cytokine , ODF , OPGL , TRANCE , Osteoprotegerin , tumor necrosis factor receptor superfamily member 11B , tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)

467353 Pan troglodytes
513836 Bos taurus
609418 Canis lupus familiaris
699955 Macaca mulatta
100599838 Nomascus leucogenys
690 Homo sapiens
8600 Homo sapiens
21943 Mus musculus
117516 Rattus norvegicus
25341 Rattus norvegicus
378803 Gallus gallus
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