Browse our anti-JAG1 (JAG1) Antibodies

On www.antibodies-online.com are 183 Jagged 1 (JAG1) Antibodies from 25 different suppliers available. Additionally we are shipping JAG1 Proteins (27) and JAG1 Kits (19) and many more products for this protein. A total of 239 JAG1 products are currently listed.
Synonyms:
ABE2, AGS, AHD, AWS, CD339, Gsfabe2, HJ1, Htu, JAG1, JAGL1, Ozz, Ser-1
list all antibodies Gene Name GeneID UniProt
JAG1 182 P78504
JAG1 29146 Q63722
JAG1 16449 Q9QXX0

Most Popular Reactivities for anti-JAG1 (JAG1) Antibodies

anti-Human JAG1 Antibodies:

anti-Rat (Rattus) JAG1 Antibodies:

anti-Mouse (Murine) JAG1 Antibodies:

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More Antibodies against JAG1 Interaction Partners

Human Jagged 1 (JAG1) interaction partners

  1. Results showed that JAG1 was significantly downregulated in miR (show MLXIP Antibodies)-26a-overexpressing osteosarcoma cells and is a direct target of miR (show MLXIP Antibodies)-26a.

  2. the effects of two Notch (show NOTCH1 Antibodies) ligands, i.e., Jagged1 and DLL1 (show DLL1 Antibodies), on murine and human hematopoiesis in vitro. Our observations indicate that the stromal expression of Notch (show NOTCH1 Antibodies) ligands increases the production of both the total and phenotypically early murine and human hematopoietic cells in the co-culture.

  3. Specific Notch3 (show NOTCH3 Antibodies) and Jag1 subcellular localization patterns may provide clues for the behavior of the corresponding tumors and could potentially be applied in the clinic for Jag1 targeting in triple-negative breast cancer patients.

  4. there is a cross-talk between Jagged1/Notch3 (show NOTCH3 Antibodies) and VEGF (show VEGFA Antibodies) in TNBC angiogenesis. Jagged1/Notch3 (show NOTCH3 Antibodies) is expected to be an important signaling pathway for TNBC progression and a potential target for TNBC neovascularization therapy.

  5. Low levels of Notch pathway genes Notch1, Notch2, Notch4 and Jagged1 correlated with poor prognostic factors such as larger tumor size, positive lymph-node status, tumor phenotype and infiltrating tumor Treg cells.

  6. Human Jagged-1 induced the proliferation and differentiation of CD133+ cord blood progenitors compared with hDll-1. Thus, hJagged-1 signaling in the bone marrow niche may be used to expand EPCs for therapeutic angiogenesis

  7. By studying leprosy as a model, we provide evidence that upregulation of JAG1 on endothelium instructs monocytes to differentiate into M1 macrophages with antimicrobial activity.

  8. High Jag1 expression is associated with metastasis in colorectal cancer.

  9. amplification of Jagged1 contributed to mRNA expression that activates the Jagged1-Notch (show NOTCH1 Antibodies) signaling pathway in liver cancer and led to poor outcome.

  10. Our data revealed that MALAT1 inhibited tongue cancer cell growth and metastasis through miR-124-dependent JAG1 regulation. In conclusion, we revealed that MALAT1 may play an oncogenic role by increasing proliferation and metastasis of tongue cancer and is a potential therapeutic target in human tongue cancer.

Mouse (Murine) Jagged 1 (JAG1) interaction partners

  1. the effects of two Notch (show NOTCH1 Antibodies) ligands, i.e., Jagged1 and DLL1 (show DLL1 Antibodies), on murine and human hematopoiesis in vitro. Our observations indicate that the stromal expression of Notch (show NOTCH1 Antibodies) ligands increases the production of both the total and phenotypically early murine and human hematopoietic cells in the co-culture.

  2. Fringe modifications at EGF8 and EGF12 enhanced Notch1 binding to and activation from Delta-like 1, while modifications at EGF6 and EGF36 (added by Manic and Lunatic but not Radical) inhibited Notch1 activation from Jagged1.

  3. A Jagged1-Hey1 (show HEY1 Antibodies) signal might mediate the impairment of angiogenesis induced by Ang II (show AGT Antibodies) during cardiac hypertrophy.

  4. Data show that Rac1 induced nuclear import of STAT3 (show STAT3 Antibodies) by physical binding, and nuclear STAT3 (show STAT3 Antibodies) directly activated the transcription of essential oocyte-specific genes, including Jagged1, GDF9 (show GDF9 Antibodies) and BMP15 (show BMP15 Antibodies).

  5. Diabetes mellitus induces Jagged1 overexpression and suppresses Notch signaling in endothelial cells. Blocking Jagged1 prevented diabetes-induced microvasculopathy and could reverse it even after 4 weeks.

  6. Jagged1 intracellular domain-mediated inhibition of Notch1 (show NOTCH1 Antibodies) signalling regulates cardiac homeostasis in the postnatal heart.

  7. endothelial Jagged1 has a role in promoting solid tumor development

  8. Jag1 expression in pulmonary capillary endothelial cells is upregulated after repeated lung injury and contributes to lung fibrosis.

  9. On a C57BL/6 background, Jag1 haploinsufficiency results in bile duct paucity in mice

  10. Jag1-induced Notch (show NOTCH1 Antibodies) activity and the subsequent (or concomitant) downregulation of the Dll4 (show DLL4 Antibodies)-mediated signalling are both required for generating haematopoietic stem cells in the embryo.

JAG1 Antigen Profile

Antigen Summary

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

Alternative names and synonyms associated with JAG1

  • jagged 1 (JAG1) antibody
  • jagged 1 (jag1) antibody
  • jagged 1 (Jag1) antibody
  • ABE2 antibody
  • AGS antibody
  • AHD antibody
  • AWS antibody
  • CD339 antibody
  • Gsfabe2 antibody
  • HJ1 antibody
  • Htu antibody
  • JAG1 antibody
  • JAGL1 antibody
  • Ozz antibody
  • Ser-1 antibody

Protein level used designations for anti-Jagged 1 (JAG1) Antibodies

jagged 1 (Alagille syndrome) , jagged 1 , protein jagged-1-like , protein jagged-1 , Serrate-1

GENE ID SPECIES
718580 Macaca mulatta
780486 Ovis aries
100474031 Ailuropoda melanoleuca
100486874 Xenopus (Silurana) tropicalis
100547052 Meleagris gallopavo
100566281 Anolis carolinensis
182 Homo sapiens
29146 Rattus norvegicus
16449 Mus musculus
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