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Browse our anti-JAG1 (JAG1) Antibodies

Full name:
anti-Jagged 1 Antibodies (JAG1)
On www.antibodies-online.com are 177 Jagged 1 (JAG1) Antibodies from 26 different suppliers available. Additionally we are shipping JAG1 Proteins (25) and JAG1 Kits (15) and many more products for this protein. A total of 227 JAG1 products are currently listed.
Synonyms:
ABE2, AGS, AHD, AWS, CD339, Gsfabe2, HJ1, Htu, JAG1, JAGL1, Ozz, Ser-1

Most Popular Reactivities for anti-JAG1 (JAG1) Antibodies

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anti-Human JAG1 Antibodies:

anti-Rat (Rattus) JAG1 Antibodies:

anti-Mouse (Murine) JAG1 Antibodies:

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Top referenced anti-JAG1 Antibodies

  1. Human Monoclonal JAG1 Primary Antibody for FACS - ABIN4900205 : Kibbie, Teles, Wang, Hong, Montoya, Krutzik, Lee, Kwon, Modlin, Cruz: Jagged1 Instructs Macrophage Differentiation in Leprosy. in PLoS pathogens 2016 (PubMed)
    Show all 5 references for ABIN4900205

  2. Dog (Canine) Monoclonal JAG1 Primary Antibody for IF, WB - ABIN968827 : Berezovska, Xia, Hyman: Notch is expressed in adult brain, is coexpressed with presenilin-1, and is altered in Alzheimer disease. in Journal of neuropathology and experimental neurology 1998 (PubMed)
    Show all 4 references for ABIN968827

  3. Chimpanzee Polyclonal JAG1 Primary Antibody for EIA, IF - ABIN401024 : Yabe, Matsumoto, Tsurumoto, Shindo: Immunohistological localization of Notch receptors and their ligands Delta and Jagged in synovial tissues of rheumatoid arthritis. in Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 2005 (PubMed)
    Show all 3 references for ABIN401024

  4. Rat (Rattus) Polyclonal JAG1 Primary Antibody for ELISA (Capture), FACS - ABIN4900585 : Stahl, Uemura, Ge, Shi, Tashima, Stanley: Roles of Pofut1 and O-fucose in mammalian Notch signaling. in The Journal of biological chemistry 2008 (PubMed)
    Show all 2 references for ABIN4900585

  5. Human Polyclonal JAG1 Primary Antibody for EIA, FACS - ABIN951303 : Foldi, Chung, Xu, Zhu, Outtz, Kitajewski, Li, Hu, Ivashkiv: Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 2 references for ABIN951303

  6. Human Polyclonal JAG1 Primary Antibody for IHC, IHC (p) - ABIN4327850 : Gunin, Petrov, Golubtzova, Vasilieva, Kornilova: Age-related changes in angiogenesis in human dermis. in Experimental gerontology 2014 (PubMed)

  7. Human Polyclonal JAG1 Primary Antibody for ICC, IF - ABIN269362 : Okamoto, Matsuda, Joetham, Lucas, Domenico, Yasutomo, Takeda, Gelfand: Jagged1 on dendritic cells and Notch on CD4+ T cells initiate lung allergic responsiveness by inducing IL-4 production. in Journal of immunology (Baltimore, Md. : 1950) 2009 (PubMed)

  8. Human Polyclonal JAG1 Primary Antibody for ICC, IF - ABIN337168 : Siar, Ha, Aung, Nakano, Tsujigiwa, Nagatsuka, Ng, Kawakami: Immunolocalization of notch signaling protein molecules in a maxillary chondrosarcoma and its recurrent tumor. in European journal of medical research 2010 (PubMed)

More Antibodies against JAG1 Interaction Partners

Human Jagged 1 (JAG1) interaction partners

  1. miR (show MLXIP Antibodies)-199a-3p targets YAP1 (show YAP1 Antibodies), downregulates Jagged1 and suppresses the Notch (show NOTCH1 Antibodies) signaling to inhibit hepatocellular carcinoma (HCC (show FAM126A Antibodies)) cell proliferation and promote apoptosis. These findings provide new insights into the mechanism by which miR (show MLXIP Antibodies)-199a-3p suppresses HCC (show FAM126A Antibodies) cell proliferation and induces apoptosis.

  2. Jagged1 activation of Notch3 (show NOTCH3 Antibodies) resulted in a significant decrease in cell proliferation while concomitantly promoting Hemangioma-pericyte maturation.

  3. expression of JAG1 is regulated by various pathways and is associated with poor prognosis through promoting the epithelial to mesenchymal transition and cell proliferation or maintaining cell survival in colorectal cancer

  4. AGS is caused by mutations in one of two genes, namely, JAG1 or NOTCH2 (show NOTCH2 Antibodies). These genes are part of the Notch (show NOTCH1 Antibodies) signaling pathway, which is involved in cell fate determination. JAG1 mutations have been identified in 70-94% of individuals with clinically diagnosed AGS

  5. On complete gene sequencing of JAG1 gene as described before, the patient was shown to be heterozygous for a known pathogenic mutationc.270delG (p.C92AfsX69) in exon 2

  6. JAG1 protein expression was significant positive correlation with lymph node metastasis, pathological grades invasive ductal carcinoma of breast.JAG1 gene methylation level in breast cancer.

  7. these findings demonstrate that 50 microM EGCG protects against ox-LDL-induced endothelial dysfunction through the Jagged-1/Notch (show NOTCH1 Antibodies) signaling pathway.

  8. PKCalpha (show PKCa Antibodies) Attenuates Jagged-1-Mediated Notch (show NOTCH1 Antibodies) Signaling in ErbB-2 (show ERBB2 Antibodies)-Positive Breast Cancer to Reverse Trastuzumab Resistance

  9. Immunohistochemical panel of CDX2, p120ctn, c-Myc, and Jagged1 proteins would be to distinguish between low/high grade dysplasia in histologically challenging cases of Barrett's esophagus.

  10. High Jagged1 expression is associated with colorectal cancer.

Mouse (Murine) Jagged 1 (JAG1) interaction partners

  1. Data show that Rac1 induced nuclear import of STAT3 (show STAT3 Antibodies) by physical binding, and nuclear STAT3 (show STAT3 Antibodies) directly activated the transcription of essential oocyte-specific genes, including Jagged1, GDF9 (show GDF9 Antibodies) and BMP15 (show BMP15 Antibodies).

  2. Diabetes mellitus induces Jagged1 overexpression and suppresses Notch signaling in endothelial cells. Blocking Jagged1 prevented diabetes-induced microvasculopathy and could reverse it even after 4 weeks.

  3. Jagged1 intracellular domain-mediated inhibition of Notch1 (show NOTCH1 Antibodies) signalling regulates cardiac homeostasis in the postnatal heart.

  4. endothelial Jagged1 has a role in promoting solid tumor development

  5. Jag1 expression in pulmonary capillary endothelial cells is upregulated after repeated lung injury and contributes to lung fibrosis.

  6. On a C57BL/6 background, Jag1 haploinsufficiency results in bile duct paucity in mice

  7. Jag1-induced Notch (show NOTCH1 Antibodies) activity and the subsequent (or concomitant) downregulation of the Dll4 (show DLL4 Antibodies)-mediated signalling are both required for generating haematopoietic stem cells in the embryo.

  8. miR (show MLXIP Antibodies)-34c overexpression inhibits the Notch (show NOTCH1 Antibodies) signaling pathway by targeting Notch1 (show NOTCH1 Antibodies) and Jaggged1 in high glucose-treated podocytes.

  9. miR-199b targeted the Notch ligand JAG1, resulting in vascular endothelial growth factor (VEGF) transcriptional activation and secretion through the transcription factor STAT3.

  10. study reports mesenchymal stromal cell-mediated immune modulation involves education and expansion of regulatory immune cells in a Jagged-1 dependent manner and reports the importance of Jagged-1 signalling in MSC (show MSC Antibodies) protection against inflammation in vivo.

JAG1 Antigen Profile

Antigen Summary

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

Alternative names and synonyms associated with JAG1

  • jagged 1 (JAG1) antibody
  • jagged 1 (jag1) antibody
  • jagged 1 (Jag1) antibody
  • ABE2 antibody
  • AGS antibody
  • AHD antibody
  • AWS antibody
  • CD339 antibody
  • Gsfabe2 antibody
  • HJ1 antibody
  • Htu antibody
  • JAG1 antibody
  • JAGL1 antibody
  • Ozz antibody
  • Ser-1 antibody

Protein level used designations for anti-Jagged 1 (JAG1) Antibodies

jagged 1 (Alagille syndrome) , jagged 1 , protein jagged-1-like , protein jagged-1 , Serrate-1

GENE ID SPECIES
718580 Macaca mulatta
780486 Ovis aries
100474031 Ailuropoda melanoleuca
100486874 Xenopus (Silurana) tropicalis
100547052 Meleagris gallopavo
100566281 Anolis carolinensis
182 Homo sapiens
29146 Rattus norvegicus
16449 Mus musculus
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