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Browse our anti-JAG1 (JAG1) Antibodies

Full name:
anti-Jagged 1 Antibodies (JAG1)
On www.antibodies-online.com are 144 Jagged 1 (JAG1) Antibodies from 25 different suppliers available. Additionally we are shipping JAG1 Proteins (24) and JAG1 Kits (12) and many more products for this protein. A total of 190 JAG1 products are currently listed.
Synonyms:
ABE2, AGS, AHD, AWS, CD339, Gsfabe2, HJ1, Htu, JAG1, JAGL1, Ozz, Ser-1

All available anti-JAG1 Antibodies

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Top referenced anti-JAG1 Antibodies

  1. Mouse (Murine) Monoclonal JAG1 Primary Antibody for Act, FACS - ABIN2662607 : Goh, Irvine, Lovelace, Donnelly, Jones, Brion, Hume, Kotze, Dalton, Ingham, Sweet: Selective induction of the Notch ligand Jagged-1 in macrophages by soluble egg antigen from Schistosoma mansoni involves ERK signalling. in Immunology 2009 (PubMed)
    Show all 6 references for ABIN2662607

  2. Dog (Canine) Monoclonal JAG1 Primary Antibody for IF, WB - ABIN968827 : Berezovska, Xia, Hyman: Notch is expressed in adult brain, is coexpressed with presenilin-1, and is altered in Alzheimer disease. in Journal of neuropathology and experimental neurology 1998 (PubMed)
    Show all 4 references for ABIN968827

  3. Chimpanzee Polyclonal JAG1 Primary Antibody for EIA, IF - ABIN401024 : Yabe, Matsumoto, Tsurumoto, Shindo: Immunohistological localization of Notch receptors and their ligands Delta and Jagged in synovial tissues of rheumatoid arthritis. in Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 2005 (PubMed)
    Show all 3 references for ABIN401024

  4. Human Polyclonal JAG1 Primary Antibody for EIA, FACS - ABIN951303 : Foldi, Chung, Xu, Zhu, Outtz, Kitajewski, Li, Hu, Ivashkiv: Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 2 references for ABIN951303

  5. Human Polyclonal JAG1 Primary Antibody for ICC, IF - ABIN337168 : Siar, Ha, Aung, Nakano, Tsujigiwa, Nagatsuka, Ng, Kawakami: Immunolocalization of notch signaling protein molecules in a maxillary chondrosarcoma and its recurrent tumor. in European journal of medical research 2010 (PubMed)

More Antibodies against JAG1 Interaction Partners

Human Jagged 1 (JAG1) interaction partners

  1. DLL4 (show DLL4 Antibodies) and JAG1 may have opposing effects on tumor angiogenesis in glioblastoma.

  2. Expression of Jag-1 in dermal microvessels was enhanced from 20 weeks of gestation to 85 years.

  3. Alagille syndrome type 1 patients have an increased risk of nonautoimmune hypothyroidism, and that variations in JAG1 gene can contribute to the pathogenesis of variable congenital thyroid defects.

  4. bone marrow stroma induces Jagged1 expression in bone metastatic prostate cancer PC3 (show PCSK1 Antibodies) cells, and this enhanced expression is mechanistically linked to the promotion of cell migration

  5. SCC (show CYP11A1 Antibodies) patients with higher JAG1 transcription had poor overall survival.

  6. Anti-estrogen resistance in human breast tumors is driven by JAG1-NOTCH4 (show NOTCH4 Antibodies)-dependent cancer stem cell activity.

  7. Data do not support association of biliary atresia with JAG1 mutations, at least in Czech patients. Rapid testing for JAG1 mutations could prevent misdiagnosis of Alagille syndrome in early infancy and improve their outcome.

  8. Jag1 is upregulated preferentially in pulmonary capillary endothelial cells in individuals with interstitial pulmonary fibrosis compared to normal lung.

  9. Jagged1 expression was correlated with higher tumor grade and invasion of breast carcinomas.

  10. Case Report: JAGGED1 gene variations in Chinese twin sisters with Alagille syndrome.

Mouse (Murine) Jagged 1 (JAG1) interaction partners

  1. endothelial Jagged1 has a role in promoting solid tumor development

  2. Jag1 expression in pulmonary capillary endothelial cells is upregulated after repeated lung injury and contributes to lung fibrosis.

  3. On a C57BL/6 background, Jag1 haploinsufficiency results in bile duct paucity in mice

  4. Jag1-induced Notch (show NOTCH1 Antibodies) activity and the subsequent (or concomitant) downregulation of the Dll4 (show DLL4 Antibodies)-mediated signalling are both required for generating haematopoietic stem cells in the embryo.

  5. miR (show MLXIP Antibodies)-34c overexpression inhibits the Notch (show NOTCH1 Antibodies) signaling pathway by targeting Notch1 (show NOTCH1 Antibodies) and Jaggged1 in high glucose-treated podocytes.

  6. miR-199b targeted the Notch ligand JAG1, resulting in vascular endothelial growth factor (VEGF) transcriptional activation and secretion through the transcription factor STAT3.

  7. study reports mesenchymal stromal cell-mediated immune modulation involves education and expansion of regulatory immune cells in a Jagged-1 dependent manner and reports the importance of Jagged-1 signalling in MSC (show MSC Antibodies) protection against inflammation in vivo.

  8. Dll1 (show DLL1 Antibodies) and Jag1, Notch (show NOTCH1 Antibodies) ligands, function redundantly and are necessary to maintain the centroacinar cells as an environmental niche in the developing pancreas.

  9. Jagged1 is a novel binding partner of Fe65, and Fe65 may act as a novel effector of Jagged1 signaling.

  10. Vehicular exhaust particles activate an AhR (show AHR Antibodies)-Jag1-Notch1 (show NOTCH1 Antibodies) cascade to promote allergic airway inflammation in concert with proasthmatic alleles.

JAG1 Antigen Profile

Antigen Summary

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

Alternative names and synonyms associated with JAG1

  • jagged 1 (JAG1) antibody
  • jagged 1 (jag1) antibody
  • jagged 1 (Jag1) antibody
  • ABE2 antibody
  • AGS antibody
  • AHD antibody
  • AWS antibody
  • CD339 antibody
  • Gsfabe2 antibody
  • HJ1 antibody
  • Htu antibody
  • JAG1 antibody
  • JAGL1 antibody
  • Ozz antibody
  • Ser-1 antibody

Protein level used designations for anti-Jagged 1 (JAG1) Antibodies

jagged 1 (Alagille syndrome) , jagged 1 , protein jagged-1-like , protein jagged-1 , Serrate-1

GENE ID SPECIES
718580 Macaca mulatta
780486 Ovis aries
100474031 Ailuropoda melanoleuca
100486874 Xenopus (Silurana) tropicalis
100547052 Meleagris gallopavo
100566281 Anolis carolinensis
182 Homo sapiens
29146 Rattus norvegicus
16449 Mus musculus
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