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Browse our anti-JAG1 (JAG1) Antibodies

Full name:
anti-Jagged 1 Antibodies (JAG1)
On are 177 Jagged 1 (JAG1) Antibodies from 26 different suppliers available. Additionally we are shipping JAG1 Proteins (25) and JAG1 Kits (13) and many more products for this protein. A total of 225 JAG1 products are currently listed.
ABE2, AGS, AHD, AWS, CD339, Gsfabe2, HJ1, Htu, JAG1, JAGL1, Ozz, Ser-1

Most Popular Reactivities for anti-JAG1 (JAG1) Antibodies

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anti-Human JAG1 Antibodies:

anti-Rat (Rattus) JAG1 Antibodies:

anti-Mouse (Murine) JAG1 Antibodies:

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Top referenced anti-JAG1 Antibodies

  1. Mouse (Murine) Monoclonal JAG1 Primary Antibody for ELISA (Capture), CyTOF - ABIN2658199 : Goh, Irvine, Lovelace, Donnelly, Jones, Brion, Hume, Kotze, Dalton, Ingham, Sweet: Selective induction of the Notch ligand Jagged-1 in macrophages by soluble egg antigen from Schistosoma mansoni involves ERK signalling. in Immunology 2009 (PubMed)
    Show all 6 references for ABIN2658199

  2. Mouse (Murine) Monoclonal JAG1 Primary Antibody for Act, FACS - ABIN2662607 : Zeng, Li, Chen: Overexpression of angiopoietin-1 increases CD133+/c-kit+ cells and reduces myocardial apoptosis in db/db mouse infarcted hearts. in PLoS ONE 2012 (PubMed)
    Show all 6 references for ABIN2662607

  3. Dog (Canine) Monoclonal JAG1 Primary Antibody for IF, WB - ABIN968827 : Berezovska, Xia, Hyman: Notch is expressed in adult brain, is coexpressed with presenilin-1, and is altered in Alzheimer disease. in Journal of neuropathology and experimental neurology 1998 (PubMed)
    Show all 4 references for ABIN968827

  4. Chimpanzee Polyclonal JAG1 Primary Antibody for EIA, IF - ABIN401024 : Yabe, Matsumoto, Tsurumoto, Shindo: Immunohistological localization of Notch receptors and their ligands Delta and Jagged in synovial tissues of rheumatoid arthritis. in Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 2005 (PubMed)
    Show all 3 references for ABIN401024

  5. Human Polyclonal JAG1 Primary Antibody for EIA, FACS - ABIN951303 : Foldi, Chung, Xu, Zhu, Outtz, Kitajewski, Li, Hu, Ivashkiv: Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 2 references for ABIN951303

  6. Human Polyclonal JAG1 Primary Antibody for ICC, IF - ABIN269362 : Okamoto, Matsuda, Joetham, Lucas, Domenico, Yasutomo, Takeda, Gelfand: Jagged1 on dendritic cells and Notch on CD4+ T cells initiate lung allergic responsiveness by inducing IL-4 production. in Journal of immunology (Baltimore, Md. : 1950) 2009 (PubMed)

  7. Human Polyclonal JAG1 Primary Antibody for ICC, IF - ABIN337168 : Siar, Ha, Aung, Nakano, Tsujigiwa, Nagatsuka, Ng, Kawakami: Immunolocalization of notch signaling protein molecules in a maxillary chondrosarcoma and its recurrent tumor. in European journal of medical research 2010 (PubMed)

More Antibodies against JAG1 Interaction Partners

Human Jagged 1 (JAG1) interaction partners

  1. AGS is caused by mutations in one of two genes, namely, JAG1 or NOTCH2 (show NOTCH2 Antibodies). These genes are part of the Notch (show NOTCH1 Antibodies) signaling pathway, which is involved in cell fate determination. JAG1 mutations have been identified in 70-94% of individuals with clinically diagnosed AGS

  2. On complete gene sequencing of JAG1 gene as described before, the patient was shown to be heterozygous for a known pathogenic mutationc.270delG (p.C92AfsX69) in exon 2

  3. JAG1 protein expression was significant positive correlation with lymph node metastasis, pathological grades invasive ductal carcinoma of breast.JAG1 gene methylation level in breast cancer.

  4. these findings demonstrate that 50 microM EGCG protects against ox-LDL-induced endothelial dysfunction through the Jagged-1/Notch (show NOTCH1 Antibodies) signaling pathway.

  5. PKCalpha (show PKCa Antibodies) Attenuates Jagged-1-Mediated Notch (show NOTCH1 Antibodies) Signaling in ErbB-2 (show ERBB2 Antibodies)-Positive Breast Cancer to Reverse Trastuzumab Resistance

  6. Immunohistochemical panel of CDX2, p120ctn, c-Myc, and Jagged1 proteins would be to distinguish between low/high grade dysplasia in histologically challenging cases of Barrett's esophagus.

  7. High Jagged1 expression is associated with colorectal cancer.

  8. High Jagged1 expression is associated with Prostatic Intraepithelial Neoplasia.

  9. findings provide evidence for a novel cell-autonomous pro-inflammatory Jagged1-Notch1 (show NOTCH1 Antibodies) pathway in endothelial cells

  10. DLL4 (show DLL4 Antibodies) and JAG1 may have opposing effects on tumor angiogenesis in glioblastoma.

Mouse (Murine) Jagged 1 (JAG1) interaction partners

  1. Diabetes mellitus induces Jagged1 overexpression and suppresses Notch signaling in endothelial cells. Blocking Jagged1 prevented diabetes-induced microvasculopathy and could reverse it even after 4 weeks.

  2. Jagged1 intracellular domain-mediated inhibition of Notch1 (show NOTCH1 Antibodies) signalling regulates cardiac homeostasis in the postnatal heart.

  3. endothelial Jagged1 has a role in promoting solid tumor development

  4. Jag1 expression in pulmonary capillary endothelial cells is upregulated after repeated lung injury and contributes to lung fibrosis.

  5. On a C57BL/6 background, Jag1 haploinsufficiency results in bile duct paucity in mice

  6. Jag1-induced Notch (show NOTCH1 Antibodies) activity and the subsequent (or concomitant) downregulation of the Dll4 (show DLL4 Antibodies)-mediated signalling are both required for generating haematopoietic stem cells in the embryo.

  7. miR (show MLXIP Antibodies)-34c overexpression inhibits the Notch (show NOTCH1 Antibodies) signaling pathway by targeting Notch1 (show NOTCH1 Antibodies) and Jaggged1 in high glucose-treated podocytes.

  8. miR-199b targeted the Notch ligand JAG1, resulting in vascular endothelial growth factor (VEGF) transcriptional activation and secretion through the transcription factor STAT3.

  9. study reports mesenchymal stromal cell-mediated immune modulation involves education and expansion of regulatory immune cells in a Jagged-1 dependent manner and reports the importance of Jagged-1 signalling in MSC (show MSC Antibodies) protection against inflammation in vivo.

  10. Dll1 (show DLL1 Antibodies) and Jag1, Notch (show NOTCH1 Antibodies) ligands, function redundantly and are necessary to maintain the centroacinar cells as an environmental niche in the developing pancreas.

JAG1 Antigen Profile

Antigen Summary

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

Alternative names and synonyms associated with JAG1

  • jagged 1 (JAG1) antibody
  • jagged 1 (jag1) antibody
  • jagged 1 (Jag1) antibody
  • ABE2 antibody
  • AGS antibody
  • AHD antibody
  • AWS antibody
  • CD339 antibody
  • Gsfabe2 antibody
  • HJ1 antibody
  • Htu antibody
  • JAG1 antibody
  • JAGL1 antibody
  • Ozz antibody
  • Ser-1 antibody

Protein level used designations for anti-Jagged 1 (JAG1) Antibodies

jagged 1 (Alagille syndrome) , jagged 1 , protein jagged-1-like , protein jagged-1 , Serrate-1

718580 Macaca mulatta
780486 Ovis aries
100474031 Ailuropoda melanoleuca
100486874 Xenopus (Silurana) tropicalis
100547052 Meleagris gallopavo
100566281 Anolis carolinensis
182 Homo sapiens
29146 Rattus norvegicus
16449 Mus musculus
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