JAG1 Products
(Jagged 1 (JAG1))
Categories
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008].
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Featured JAG1 Categories
JAG1 Antibodies
High quality antibodies with extensive validation data.
JAG1 ELISA Kits
Reliable ELISA kits for a wide range of species.
JAG1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended JAG1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, FM
Validations
- (2)
- (3)
- (1)
Cat. No.
ABIN129524
Quantity
500 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC, Neut
Validations
- (4)
Cat. No.
ABIN7193228
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7438310
Quantity
100 μL
Datasheet
Datasheet
Recommended JAG1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (6)
- (5)
Cat. No.
ABIN6730961
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968074
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957228
Quantity
96 tests
Datasheet
Datasheet
Recommended JAG1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308267
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308269
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN1344183
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our JAG1 products
: "Epigenetically heterogeneous tumor cells direct collective invasion through filopodia-driven fibronectin micropatterning." in: Science advances, Vol. 6, Issue 30, pp. eaaz6197, (2020) (PubMed).: "Notch signalling defines dorsal root ganglia neuroglial fate choice during early neural crest cell migration." in: BMC neuroscience, Vol. 20, Issue 1, pp. 21, (2019) (PubMed).
: "NOTCH-mediated non-cell autonomous regulation of chromatin structure during senescence." in: Nature communications, Vol. 9, Issue 1, pp. 1840, (2018) (PubMed).
: "Muscle Satellite Cell Cross-Talk with a Vascular Niche Maintains Quiescence via VEGF and Notch Signaling." in: Cell stem cell, Vol. 23, Issue 4, pp. 530-543.e9, (2018) (PubMed).
: "NOTCH1 mediates a switch between two distinct secretomes during senescence." in: Nature cell biology, Vol. 18, Issue 9, pp. 979-92, (2017) (PubMed).
: "Notch-Jagged signalling can give rise to clusters of cells exhibiting a hybrid epithelial/mesenchymal phenotype." in: Journal of the Royal Society, Interface, Vol. 13, Issue 118, (2017) (PubMed).
: "Jagged1 Instructs Macrophage Differentiation in Leprosy." in: PLoS pathogens, Vol. 12, Issue 8, pp. e1005808, (2016) (PubMed).
: "PI3 kinase inhibition improves vascular malformations in mouse models of hereditary haemorrhagic telangiectasia." in: Nature communications, Vol. 7, pp. 13650, (2016) (PubMed).
: "Notch Signaling Induces Root Resorption via RANKL and IL-6 from hPDL Cells." in: Journal of dental research, (2014) (PubMed).
: "Ligation of ICAM-1 on human aortic valve interstitial cells induces the osteogenic response: A critical role of the Notch1-NF-?B pathway in BMP-2 expression." in: Biochimica et biophysica acta, Vol. 1843, Issue 11, pp. 2744-53, (2014) (PubMed).
Synonyms and alternative names related to JAG1
jagged 1 (JAG1), jagged 1 (Jag1), jagged 1 (jag1), jagged 1b (jag1b), jagged 1a (jag1a), jagged 1 L homeolog (jag1.L), ABE2, AGS, AHD, AWS, cb243, CD339, Gsfabe2, HJ1, Htu, JAG1, jag1, jag3, jagged1, JAGL1, Ozz, sb:cb243, Ser-1, serrate, serrate-1, serrateC, x-serrate-1Protein level used designations for JAG1
- protein jagged-1
- Serrate-1
- jagged 1 (Alagille syndrome)
- jagged 1
- protein jagged-1-like
- jagged3
- kmi
- protein jagged-1b
- puc
- unp1069
- jagged1
- protein jagged-1a
- jagged 1 L homeolog
- C-Serate-1 protein
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