JAG1 antibody

Catalog No. ABIN1169436

The Mouse Monoclonal anti-JAG1 antibody (Clone J1G53-3) (ABIN1169436) specifically detects JAG1 in WB, IHC, ELISA and FACS. The antibody is reactive with Human samples.

Quick Overview for JAG1 antibody (ABIN1169436)

Target: JAG1 (Jagged 1 (JAG1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This JAG1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Clone: J1G53-3

Product Details anti-JAG1 Antibody

Purpose: anti-Jagged-1 (human), mAb (J1G53-3)

Specificity: Recognizes human Jagged-1. Detects a band of ~180 kDa by Western blot.

Characteristics: Monoclonal Antibody. Recognizes human Jagged-1. Detects a band of ~180 kDa by Western blot. Isotype: Mouse IgG1kappa. Clone: J1G53-3. Applications: ELISA, FACS, IHC, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF).

Sterility: 0.2 μm filtered

Immunogen: Recombinant human Jagged-1.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Preservative: Without preservative

Handling Advice: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Expiry Date: 12 months

Target Details for JAG1

Target: JAG1 (Jagged 1 (JAG1))

Alternative Name: Jagged-1

Background:

Alternate Names/Synonyms: Protein Jagged-1, CD339, JAG1

Product Description: Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF).

UniProt: P78504

Pathways: Notch Signaling, Stem Cell Maintenance