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Browse our JAG1 (JAG1) ELISA Kits

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Jagged 1 ELISA Kits (JAG1)
On are 17 Jagged 1 (JAG1) ELISA Kits from 8 different suppliers available. Additionally we are shipping JAG1 Antibodies (178) and JAG1 Proteins (25) and many more products for this protein. A total of 230 JAG1 products are currently listed.
ABE2, AGS, AHD, AWS, CD339, Gsfabe2, HJ1, Htu, JAG1, JAGL1, Ozz, Ser-1

JAG1 (JAG1) ELISA Kits by Reactivity

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Top referenced JAG1 ELISA Kits

  1. Human JAG1 ELISA Kit for Sandwich ELISA - ABIN417745 : Zeng, Jin, Ao, Cleveland, Song, Xu, Fullerton, Meng: Cross-talk between the Toll-like receptor 4 and Notch1 pathways augments the inflammatory response in the interstitial cells of stenotic human aortic valves. in Circulation 2012 (PubMed)
    Show all 6 references for ABIN417745

More ELISA Kits for JAG1 Interaction Partners

Human Jagged 1 (JAG1) interaction partners

  1. Low levels of Notch pathway genes Notch1, Notch2, Notch4 and Jagged1 correlated with poor prognostic factors such as larger tumor size, positive lymph-node status, tumor phenotype and infiltrating tumor Treg cells.

  2. Human Jagged-1 induced the proliferation and differentiation of CD133+ cord blood progenitors compared with hDll-1. Thus, hJagged-1 signaling in the bone marrow niche may be used to expand EPCs for therapeutic angiogenesis

  3. By studying leprosy as a model, we provide evidence that upregulation of JAG1 on endothelium instructs monocytes to differentiate into M1 macrophages with antimicrobial activity.

  4. High Jag1 expression is associated with metastasis in colorectal cancer.

  5. amplification of Jagged1 contributed to mRNA expression that activates the Jagged1-Notch (show NOTCH1 ELISA Kits) signaling pathway in liver cancer and led to poor outcome.

  6. Our data revealed that MALAT1 inhibited tongue cancer cell growth and metastasis through miR-124-dependent JAG1 regulation. In conclusion, we revealed that MALAT1 may play an oncogenic role by increasing proliferation and metastasis of tongue cancer and is a potential therapeutic target in human tongue cancer.

  7. Positive Jagged1 and DLL4 (show DLL4 ELISA Kits) expression is closely correlated with severe clinicopathological characteristics and poor prognosis in patients with pancreatic ductal carcinoma.

  8. miR (show MLXIP ELISA Kits)-199a-3p targets YAP1 (show YAP1 ELISA Kits), downregulates Jagged1 and suppresses the Notch (show NOTCH1 ELISA Kits) signaling to inhibit hepatocellular carcinoma (HCC (show FAM126A ELISA Kits)) cell proliferation and promote apoptosis. These findings provide new insights into the mechanism by which miR (show MLXIP ELISA Kits)-199a-3p suppresses HCC (show FAM126A ELISA Kits) cell proliferation and induces apoptosis.

  9. Jagged1 activation of Notch3 (show NOTCH3 ELISA Kits) resulted in a significant decrease in cell proliferation while concomitantly promoting Hemangioma-pericyte maturation.

  10. expression of JAG1 is regulated by various pathways and is associated with poor prognosis through promoting the epithelial to mesenchymal transition and cell proliferation or maintaining cell survival in colorectal cancer

Mouse (Murine) Jagged 1 (JAG1) interaction partners

  1. Fringe modifications at EGF8 and EGF12 enhanced Notch1 binding to and activation from Delta-like 1, while modifications at EGF6 and EGF36 (added by Manic and Lunatic but not Radical) inhibited Notch1 activation from Jagged1.

  2. A Jagged1-Hey1 (show HEY1 ELISA Kits) signal might mediate the impairment of angiogenesis induced by Ang II (show AGT ELISA Kits) during cardiac hypertrophy.

  3. Data show that Rac1 induced nuclear import of STAT3 (show STAT3 ELISA Kits) by physical binding, and nuclear STAT3 (show STAT3 ELISA Kits) directly activated the transcription of essential oocyte-specific genes, including Jagged1, GDF9 (show GDF9 ELISA Kits) and BMP15 (show BMP15 ELISA Kits).

  4. Diabetes mellitus induces Jagged1 overexpression and suppresses Notch signaling in endothelial cells. Blocking Jagged1 prevented diabetes-induced microvasculopathy and could reverse it even after 4 weeks.

  5. Jagged1 intracellular domain-mediated inhibition of Notch1 (show NOTCH1 ELISA Kits) signalling regulates cardiac homeostasis in the postnatal heart.

  6. endothelial Jagged1 has a role in promoting solid tumor development

  7. Jag1 expression in pulmonary capillary endothelial cells is upregulated after repeated lung injury and contributes to lung fibrosis.

  8. On a C57BL/6 background, Jag1 haploinsufficiency results in bile duct paucity in mice

  9. Jag1-induced Notch (show NOTCH1 ELISA Kits) activity and the subsequent (or concomitant) downregulation of the Dll4 (show DLL4 ELISA Kits)-mediated signalling are both required for generating haematopoietic stem cells in the embryo.

  10. miR (show MLXIP ELISA Kits)-34c overexpression inhibits the Notch (show NOTCH1 ELISA Kits) signaling pathway by targeting Notch1 (show NOTCH1 ELISA Kits) and Jaggged1 in high glucose-treated podocytes.

JAG1 Antigen Profile

Antigen Summary

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

Alternative names and synonyms associated with JAG1

  • jagged 1 (JAG1) Elisa Kit
  • jagged 1 (jag1) Elisa Kit
  • jagged 1 (Jag1) Elisa Kit
  • ABE2 Elisa Kit
  • AGS Elisa Kit
  • AHD Elisa Kit
  • AWS Elisa Kit
  • CD339 Elisa Kit
  • Gsfabe2 Elisa Kit
  • HJ1 Elisa Kit
  • Htu Elisa Kit
  • JAG1 Elisa Kit
  • JAGL1 Elisa Kit
  • Ozz Elisa Kit
  • Ser-1 Elisa Kit

Protein level used designations for Jagged 1 (JAG1) ELISA Kits

jagged 1 (Alagille syndrome) , jagged 1 , protein jagged-1-like , protein jagged-1 , Serrate-1

718580 Macaca mulatta
780486 Ovis aries
100474031 Ailuropoda melanoleuca
100486874 Xenopus (Silurana) tropicalis
100547052 Meleagris gallopavo
100566281 Anolis carolinensis
182 Homo sapiens
29146 Rattus norvegicus
16449 Mus musculus
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