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Browse our JAG1 (JAG1) ELISA Kits

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Jagged 1 ELISA Kits (JAG1)
On are 15 Jagged 1 (JAG1) ELISA Kits from 7 different suppliers available. Additionally we are shipping JAG1 Antibodies (177) and JAG1 Proteins (25) and many more products for this protein. A total of 227 JAG1 products are currently listed.
ABE2, AGS, AHD, AWS, CD339, Gsfabe2, HJ1, Htu, JAG1, JAGL1, Ozz, Ser-1

JAG1 (JAG1) ELISA Kits by Reactivity

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Top referenced JAG1 ELISA Kits

  1. Human JAG1 ELISA Kit for Sandwich ELISA - ABIN417745 : Zeng, Jin, Ao, Cleveland, Song, Xu, Fullerton, Meng: Cross-talk between the Toll-like receptor 4 and Notch1 pathways augments the inflammatory response in the interstitial cells of stenotic human aortic valves. in Circulation 2012 (PubMed)
    Show all 6 references for ABIN417745

More ELISA Kits for JAG1 Interaction Partners

Human Jagged 1 (JAG1) interaction partners

  1. miR (show MLXIP ELISA Kits)-199a-3p targets YAP1 (show YAP1 ELISA Kits), downregulates Jagged1 and suppresses the Notch (show NOTCH1 ELISA Kits) signaling to inhibit hepatocellular carcinoma (HCC (show FAM126A ELISA Kits)) cell proliferation and promote apoptosis. These findings provide new insights into the mechanism by which miR (show MLXIP ELISA Kits)-199a-3p suppresses HCC (show FAM126A ELISA Kits) cell proliferation and induces apoptosis.

  2. Jagged1 activation of Notch3 (show NOTCH3 ELISA Kits) resulted in a significant decrease in cell proliferation while concomitantly promoting Hemangioma-pericyte maturation.

  3. expression of JAG1 is regulated by various pathways and is associated with poor prognosis through promoting the epithelial to mesenchymal transition and cell proliferation or maintaining cell survival in colorectal cancer

  4. AGS is caused by mutations in one of two genes, namely, JAG1 or NOTCH2 (show NOTCH2 ELISA Kits). These genes are part of the Notch (show NOTCH1 ELISA Kits) signaling pathway, which is involved in cell fate determination. JAG1 mutations have been identified in 70-94% of individuals with clinically diagnosed AGS

  5. On complete gene sequencing of JAG1 gene as described before, the patient was shown to be heterozygous for a known pathogenic mutationc.270delG (p.C92AfsX69) in exon 2

  6. JAG1 protein expression was significant positive correlation with lymph node metastasis, pathological grades invasive ductal carcinoma of breast.JAG1 gene methylation level in breast cancer.

  7. these findings demonstrate that 50 microM EGCG protects against ox-LDL-induced endothelial dysfunction through the Jagged-1/Notch (show NOTCH1 ELISA Kits) signaling pathway.

  8. PKCalpha (show PKCa ELISA Kits) Attenuates Jagged-1-Mediated Notch (show NOTCH1 ELISA Kits) Signaling in ErbB-2 (show ERBB2 ELISA Kits)-Positive Breast Cancer to Reverse Trastuzumab Resistance

  9. Immunohistochemical panel of CDX2, p120ctn, c-Myc, and Jagged1 proteins would be to distinguish between low/high grade dysplasia in histologically challenging cases of Barrett's esophagus.

  10. High Jagged1 expression is associated with colorectal cancer.

Mouse (Murine) Jagged 1 (JAG1) interaction partners

  1. Data show that Rac1 induced nuclear import of STAT3 (show STAT3 ELISA Kits) by physical binding, and nuclear STAT3 (show STAT3 ELISA Kits) directly activated the transcription of essential oocyte-specific genes, including Jagged1, GDF9 (show GDF9 ELISA Kits) and BMP15 (show BMP15 ELISA Kits).

  2. Diabetes mellitus induces Jagged1 overexpression and suppresses Notch signaling in endothelial cells. Blocking Jagged1 prevented diabetes-induced microvasculopathy and could reverse it even after 4 weeks.

  3. Jagged1 intracellular domain-mediated inhibition of Notch1 (show NOTCH1 ELISA Kits) signalling regulates cardiac homeostasis in the postnatal heart.

  4. endothelial Jagged1 has a role in promoting solid tumor development

  5. Jag1 expression in pulmonary capillary endothelial cells is upregulated after repeated lung injury and contributes to lung fibrosis.

  6. On a C57BL/6 background, Jag1 haploinsufficiency results in bile duct paucity in mice

  7. Jag1-induced Notch (show NOTCH1 ELISA Kits) activity and the subsequent (or concomitant) downregulation of the Dll4 (show DLL4 ELISA Kits)-mediated signalling are both required for generating haematopoietic stem cells in the embryo.

  8. miR (show MLXIP ELISA Kits)-34c overexpression inhibits the Notch (show NOTCH1 ELISA Kits) signaling pathway by targeting Notch1 (show NOTCH1 ELISA Kits) and Jaggged1 in high glucose-treated podocytes.

  9. miR-199b targeted the Notch ligand JAG1, resulting in vascular endothelial growth factor (VEGF) transcriptional activation and secretion through the transcription factor STAT3.

  10. study reports mesenchymal stromal cell-mediated immune modulation involves education and expansion of regulatory immune cells in a Jagged-1 dependent manner and reports the importance of Jagged-1 signalling in MSC (show MSC ELISA Kits) protection against inflammation in vivo.

JAG1 Antigen Profile

Antigen Summary

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

Alternative names and synonyms associated with JAG1

  • jagged 1 (JAG1) Elisa Kit
  • jagged 1 (jag1) Elisa Kit
  • jagged 1 (Jag1) Elisa Kit
  • ABE2 Elisa Kit
  • AGS Elisa Kit
  • AHD Elisa Kit
  • AWS Elisa Kit
  • CD339 Elisa Kit
  • Gsfabe2 Elisa Kit
  • HJ1 Elisa Kit
  • Htu Elisa Kit
  • JAG1 Elisa Kit
  • JAGL1 Elisa Kit
  • Ozz Elisa Kit
  • Ser-1 Elisa Kit

Protein level used designations for Jagged 1 (JAG1) ELISA Kits

jagged 1 (Alagille syndrome) , jagged 1 , protein jagged-1-like , protein jagged-1 , Serrate-1

718580 Macaca mulatta
780486 Ovis aries
100474031 Ailuropoda melanoleuca
100486874 Xenopus (Silurana) tropicalis
100547052 Meleagris gallopavo
100566281 Anolis carolinensis
182 Homo sapiens
29146 Rattus norvegicus
16449 Mus musculus
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