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Browse our anti-TNFRSF10B (TNFRSF10B) Antibodies

Full name:
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b Antibodies (TNFRSF10B)
On www.antibodies-online.com are 299 Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) Antibodies from 35 different suppliers available. Additionally we are shipping TNFRSF10B Proteins (41) and TNFRSF10B Kits (10) and many more products for this protein. A total of 370 TNFRSF10B products are currently listed.
Synonyms:
CD262, DR5, KILLER, KILLER/DR5, Ly98, MK, TNFRSF10B, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, xDR-M1, xDR-M2, ZTNFR9
list all antibodies Gene Name GeneID UniProt
TNFRSF10B 364420  
TNFRSF10B 8795 O14763
TNFRSF10B 21933 Q9QZM4

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All available anti-TNFRSF10B Antibodies

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Top referenced anti-TNFRSF10B Antibodies

  1. Human Monoclonal TNFRSF10B Primary Antibody for Func - ABIN1106164 : Chen, Chou, Chang, Chen: Proteasome inhibitors enhance TRAIL-induced apoptosis through the intronic regulation of DR5: involvement of NF-kappa B and reactive oxygen species-mediated p53 activation. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
    Show all 2 references for ABIN1106164

  2. Human Monoclonal TNFRSF10B Primary Antibody for FACS - ABIN1106166 : Mérino, Lalaoui, Morizot, Schneider, Solary, Micheau: Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2. in Molecular and cellular biology 2006 (PubMed)
    Show all 2 references for ABIN1106166

  3. Human Monoclonal TNFRSF10B Primary Antibody for FACS - ABIN238400 : Corallini, Milani, Nicolin, Secchiero: TRAIL, caspases and maturation of normal and leukemic myeloid precursors. in Leukemia & lymphoma 2006 (PubMed)

  4. Human Polyclonal TNFRSF10B Primary Antibody for WB - ABIN2792103 : Baritaki, Suzuki, Umezawa, Spandidos, Berenson, Daniels, Penichet, Jazirehi, Palladino, Bonavida: Inhibition of Yin Yang 1-dependent repressor activity of DR5 transcription and expression by the novel proteasome inhibitor NPI-0052 contributes to its TRAIL-enhanced apoptosis in cancer cells. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)

  5. Human Polyclonal TNFRSF10B Primary Antibody for WB - ABIN222914 : Erster, Mihara, Kim, Petrenko, Moll: In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation. in Molecular and cellular biology 2004 (PubMed)

More Antibodies against TNFRSF10B Interaction Partners

Human Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) interaction partners

  1. Synthetic lipid bilayers displaying the membrane protein ligand Apo2L (show TNFSF10 Antibodies)/TRAIL were used to stimulate death receptor-expressing cells in a modular, scalable format

  2. These results demonstrate that increased apoptosis induced by TRAIL is associated with increased expression of DR5 that is mediated by HBX through NF-kappaB (show NFKB1 Antibodies) pathway.

  3. Methionine Deprivation Induces a Targetable Vulnerability in Triple-Negative Breast Cancer Cells by Enhancing TRAIL Receptor-2 Expression

  4. Studied an array of TRAIL-R1 and TRAIL-R2 specific variants on pancreatic cancer cells.

  5. Shogaol increased death receptor 5 (DR5) levels. Moreover, knockdown of survivin (show BIRC5 Antibodies) sensitized colon cancer cells to resistant of TRAIL-induced apoptosis.

  6. FTY720 ehances TRAIL-induced apoptosis through up-regulation of DR5 and down-regulation of Mcl-1 (show MCL1 Antibodies) in human kidney cancer cells.

  7. The expression of two proapoptotic genes, FAS (show FAS Antibodies) and DR5, was significantly lower in tumor samples than in adjacent normal tissues

  8. In an osteotropic variant of MDA-MB-231 breast cancer cells, TRAIL-R2 knockdown leads to downregulation of HMGA2, p-Src (show SRC Antibodies), p-Akt (show AKT1 Antibodies) and CXCR4 (show CXCR4 Antibodies) and increased E-cadherin (show CDH1 Antibodies) expression. These changes diminished occurrence of skeletal metastases in vivo.

  9. mutant genotype (CT+TT) of DR5 (rs1047266) may exert a negative synergistic effect on crohn disease.

  10. Studied the apoptosis of hepatic stellate cells induced by SEA (show Slc25a1 Antibodies); found it could be reduced in hepatic stellate cells that were treated with p53 (show TP53 Antibodies)-specific siRNA and in hepatic stellate cells that were treated with DR5-specific shRNA.

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) interaction partners

  1. Malignant transformation in the endometrium is related to reduction of membrane DR4 (show HLADRB4 Antibodies) and DR5 expression.

  2. TRAIL expression by osteoclast-like cells is increased in the presence of RANKL (show TNFSF11 Antibodies) and after scraping; DcR2 (show TNFRSF10D Antibodies) expression peaks at 24 hours, and and decreases at 5 days; DR5 expression peaks at 5 days

  3. Induction of death receptor 5 expression in tumor vasculature by perifosine restores the vascular disruption activity of TRAIL-expressing CD34 (show CD34 Antibodies)(+) cells.

  4. TRAIL-DR5 interaction promoted malignant behaviors of B16F10 cells.

  5. results suggest that the transmembrane domains together with their adjacent stalk regions can play a major role in control of death receptor activation thereby contributing to cell type specific differences in TRAILR1 and TRAILR2 signaling

  6. DR5 is selectively expressed by neuroprogenitor cells and newborn neurons.

  7. Results suggest that excessive iodine could induce TRAIL and DR5 abnormal expression in thyroid. TRAIL band with DR5 to promote follicular cells apoptosis thus mediate thyroid destruction in EAT.

  8. NK cells inhibit dendritic cell cross-priming, but not direct priming, in a TRAIL/DR5-dependent manner.

  9. Antibody-based therapy targeting DR5 is an efficient strategy not only to eliminate TRAIL-sensitive tumor cells.

  10. binding of Fas-associated death domain (FADD) to the tumor necrosis factor-related apoptosis-inducing ligand receptor DR5 is regulated by the death effector domain of FADD

TNFRSF10B Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.

Alternative names and synonyms associated with TNFRSF10B

  • tumor necrosis factor receptor superfamily, member 10b (Tnfrsf10b) antibody
  • tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B) antibody
  • tumor necrosis factor receptor superfamily, member 10b (tnfrsf10b-b) antibody
  • tumor necrosis factor receptor superfamily, member 10b (tnfrsf10b) antibody
  • CD262 antibody
  • DR5 antibody
  • KILLER antibody
  • KILLER/DR5 antibody
  • Ly98 antibody
  • MK antibody
  • TNFRSF10B antibody
  • TRAIL-R2 antibody
  • TRAILR2 antibody
  • TRICK2 antibody
  • TRICK2A antibody
  • TRICK2B antibody
  • TRICKB antibody
  • xDR-M1 antibody
  • xDR-M2 antibody
  • ZTNFR9 antibody

Protein level used designations for TNFRSF10B

tumor necrosis factor receptor superfamily, member 10b , death receptor-M2 , death receptor-M1 , Fas-like protein , TNF-related apoptosis-inducing ligand receptor 2 , apoptosis inducing protein TRICK2A/2B , apoptosis inducing receptor TRAIL-R2 , cytotoxic TRAIL receptor-2 , death domain containing receptor for TRAIL/Apo-2L , death receptor 5 , p53-regulated DNA damage-inducible cell death receptor(killer) , tumor necrosis factor receptor superfamily member 10B , tumor necrosis factor receptor-like protein ZTNFR9 , KILLER/DR5 TRAIL death-inducing receptor

GENE ID SPECIES
364420 Rattus norvegicus
282533 Bos taurus
404687 Xenopus laevis
404688 Xenopus laevis
448240 Xenopus (Silurana) tropicalis
742898 Pan troglodytes
8795 Homo sapiens
21933 Mus musculus
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