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TNFRSF10B antibody

TNFRSF10B Reactivity: Human, Mouse WB, ICC Host: Mouse Monoclonal unconjugated
Catalog No. ABIN6241224
  • Target See all TNFRSF10B Antibodies
    TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
    Reactivity
    • 98
    • 17
    • 4
    • 1
    • 1
    Human, Mouse
    Host
    • 64
    • 38
    • 3
    • 1
    • 1
    • 1
    Mouse
    Clonality
    • 61
    • 44
    • 2
    Monoclonal
    Conjugate
    • 72
    • 10
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TNFRSF10B antibody is un-conjugated
    Application
    • 73
    • 35
    • 31
    • 25
    • 17
    • 15
    • 15
    • 13
    • 12
    • 11
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC)
    Immunogen
    Recombinant Protein
    Top Product
    Discover our top product TNFRSF10B Primary Antibody
  • Application Notes
    WB: 1:500-1:2000. ICC: 1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Storage
    4 °C,-20 °C
  • Target
    TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
    Alternative Name
    DR5 (TNFRSF10B Products)
    Synonyms
    TNFRSF10B antibody, dr5 antibody, cd262 antibody, killer antibody, trick2 antibody, trickb antibody, xDR-M1 antibody, xDR-M2 antibody, ztnfr9 antibody, trailr2 antibody, trick2a antibody, trick2b antibody, CD262 antibody, DR5 antibody, KILLER antibody, KILLER/DR5 antibody, TRAIL-R2 antibody, TRAILR2 antibody, TRICK2 antibody, TRICK2A antibody, TRICK2B antibody, TRICKB antibody, ZTNFR9 antibody, Ly98 antibody, MK antibody, tumor necrosis factor receptor superfamily, member 10b antibody, tumor necrosis factor receptor superfamily member 10b S homeolog antibody, tumor necrosis factor receptor superfamily member 10b L homeolog antibody, tumor necrosis factor receptor superfamily member 10b antibody, TNF receptor superfamily member 10b antibody, Tnfrsf10b antibody, TNFRSF10B antibody, tnfrsf10b.S antibody, tnfrsf10b.L antibody, tnfrsf10b antibody
    Background
    Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF- kappa-B. Essential for ER stress-induced apoptosis.
    UniProt
    O14763
    Pathways
    p53 Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity
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