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anti-Rat (Rattus) CDX2 Antibodies:
anti-Human CDX2 Antibodies:
anti-Mouse (Murine) CDX2 Antibodies:
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Human Monoclonal CDX2 Primary Antibody for BI, WB - ABIN967663
Hinoi, Loda, Fearon: Silencing of CDX2 expression in colon cancer via a dominant repression pathway. in The Journal of biological chemistry 2003
Show all 6 Pubmed References
Human Polyclonal CDX2 Primary Antibody for IHC (p), IP - ABIN151575
Verzi, Hatzis, Sulahian, Philips, Schuijers, Shin, Freed, Lynch, Dang, Brown, Clevers, Liu, Shivdasani: TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions. in Proceedings of the National Academy of Sciences of the United States of America 2010
Show all 5 Pubmed References
Human Monoclonal CDX2 Primary Antibody for FACS, ELISA - ABIN1724921
Lee, Vogt, Hsiao, Osunkoya: CDX-2 expression in malignant germ cell tumors of the testes, intratubular germ cell neoplasia, and normal seminiferous tubules. in Tumour biology 2012
Show all 2 Pubmed References
Human Monoclonal CDX2 Primary Antibody for ELISA, WB - ABIN1724918
Liu, Zhang, Zhan, Brock, Herman, Guo: CDX2 serves as a Wnt signaling inhibitor and is frequently methylated in lung cancer. in Cancer biology & therapy 2012
Show all 2 Pubmed References
Human Monoclonal CDX2 Primary Antibody for IHC (p), IHC - ABIN152122
Flisikowska, Merkl, Landmann, Eser, Rezaei, Cui, Kurome, Zakhartchenko, Kessler, Wieland, Rottmann, Schmid, Schneider, Kind, Wolf, Saur, Schnieke: A porcine model of familial adenomatous polyposis. in Gastroenterology 2012
Human Polyclonal CDX2 Primary Antibody for ELISA, WB - ABIN251330
Qualtrough, Hinoi, Fearon, Paraskeva: Expression of CDX2 in normal and neoplastic human colon tissue and during differentiation of an in vitro model system. in Gut 2002
Human Monoclonal CDX2 Primary Antibody for ELISA, WB - ABIN560320
Zulueta, Caretti, Signorelli, Dallolio, Trinchera: Transcriptional control of the B3GALT5 gene by a retroviral promoter and methylation of distant regulatory elements. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2014
Cow (Bovine) Polyclonal CDX2 Primary Antibody for WB - ABIN2777319
Saad, Cho, Silverman, Liu: Usefulness of Cdx2 in separating mucinous bronchioloalveolar adenocarcinoma of the lung from metastatic mucinous colorectal adenocarcinoma. in American journal of clinical pathology 2004
Show all 2 Pubmed References
These results provide evidence that CDX2 plays an essential role in functional trophectoderm formation during primate embryonic development.
The data presented provide a novel insight into how CDX2 is implicated in the transcriptional regulation of LAMC2 (show LAMC2 Antibodies) in intestinal epithelial cells, a function that is impaired during mucosal inflammation where a high level of TNF-alpha (show TNF Antibodies) is present.
Cytapheresis might induce CDX2 expression without affecting the cell proliferation, thus resulting in mucosal healing with goblet cell restoration.
SOX2 (show SOX2 Antibodies) expression induces a cellular stem cell state in human colorectal cancer (CRC (show CALR Antibodies)) with a decreased expression of CDX2. Furthermore, a down-regulated expression of CDX2 results in a poor patient prognosis in CRC (show CALR Antibodies).
A small subset (5%) of hepatocellular carcinomas are CDX2 positive.
A new organ culture system for adult murine oesophagus is described. Using this, Cdx2 and HNF4alpha (show HNF4A Antibodies) were ectopically expressed by adenoviral infection. We demonstrate the expression of CDX2 and HNF4alpha (show HNF4A Antibodies) in human biopsy samples.
Colon cancer cells expressing CDX2 are less deformable, a feature that has been shown to correlate with poor metastatic potential.
Results show that CDX2 and Fbw7 (show FBXW7 Antibodies) expression is inversely correlated during colon cell differentiation and that CDX2 expression is regulated by Fbw7 (show FBXW7 Antibodies) in a GSK3b (show GSK3b Antibodies)-dependent manner.
Aberrant DNA methylation (show HELLS Antibodies) of SOX2 (show SOX2 Antibodies) and CDX2 genes contributes to the development of IM. Notably, SOX2 (show SOX2 Antibodies) may play a role in establishing and maintaining the methylation status of the CDX2 gene in gastric tissues and cells.
Strong expression of CDX2 was demonstrated only in the mature colonic epithelium of teratomas in both primary and metastatic germ cell tumors of the testis.
Cdx (show CDX1 Antibodies) members interact with the SWI (show SMARCA1 Antibodies)-SNF (show SNRPA Antibodies) complex and make direct contact with Brg1 (show SMARCA4 Antibodies), a catalytic member of SWI (show SMARCA1 Antibodies)-SNF (show SNRPA Antibodies). Both Cdx2 and Brg1 (show SMARCA4 Antibodies) co-occupy a number of Cdx (show CDX1 Antibodies) target genes, and both factors are necessary for transcriptional regulation of such targets. Finally, Cdx2 and Brg1 (show SMARCA4 Antibodies) occupancy occurs coincident with chromatin remodeling at some of these loci.
these results provide further insight into the functional diversity of CDX2 in early mammalian embryos.
showed novel molecular regulation of CDX2 on Oct4 (show POU5F1 Antibodies), and provided important clues for clarifying the mechanism of interaction between CDX2 and Oct4 (show POU5F1 Antibodies) in embryo of mammals other than mouse
The authors identify a Cdx2-responsive segment of HoxA, immediately 5' to the recently defined regulatory domain orchestrating initial transcription of the first Hox (show MSH2 Antibodies) gene.
Cdx1 (show CDX1 Antibodies)-Cdx2 double null mutants exhibited loss of primitive erythroblasts, aberrant vascular remodelling of the yolk sac (show ADCY10 Antibodies) and a block in hematopoietic differentiation from yolk sac (show ADCY10 Antibodies)-derived cells in culture.
this study shows that Aloe vera (show IGF2BP3 Antibodies) gel suppresses colitis-related colon carcinogenesis via increased expression of CDX-2, a tumor suppressor in colorectal cancer
Results point out the complex interplay between the DSB DNA repair activity and the homeoproteins HoxB7 (show HOXB7 Antibodies) and Cdx2 in colon cancer cells.
CDX2 is required for proliferation and differentiation of intestinal stem cells. Direct CDX2 targets in ISCs (show NFS1 Antibodies) may be activated or repressed.
cells in preimplantation embryos that localized in an initial outer position initiated the expression of Cdx2. cells that changed their position from an outer to an inner position downregulated Cdx2 expression and contributed to the inner cell mass.
findings illuminated a role for NOD1 (show NOD1 Antibodies) signaling in attenuating H. pylori-induced Cdx2 expression in gastric epithelial cells
Overexpression of CDX2 inhibits the growth of the gastric cancer cells in vivo and in vitro.
results thus indicate that CDX2 is not required for TE formation during bovine development; nevertheless, it is necessary for maintaining TE integrity.
This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis.
caudal type homeobox 2
, caudal type homeobox transcription factor 2
, caudal type homeo box transcription factor 2
, homeobox protein CDX-2
, caudal-type homeobox protein 2
, caudal type homeo box 2
, caudal-type homeobox transcription factor 2