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Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (C-Term) Peptide

Details for Product No. ABIN1381962
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Protein Name
Synonyms IRAK1, IRAK, pelle, AA408924, IRAK-1, IRAK1-S, Il1rak, Plpk, mPLK, RGD1563841
Protein Region
C-Term
Origin
Human
(1)
Application
Blocking Peptide (BP)
Pubmed 3 references available
Quantity 0.05 mg
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Catalog No. ABIN1381962
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Characteristics 13 amino acids near the carboxy terminus of human IRAK.
Human
Alternative Name IRAK
Research Area Immunology, Innate Immunity, Atherosclerosis, Cytokines, Receptors, Inflammation
Application Notes IRAK peptide is used for blocking the activity of IRAK.
Restrictions For Research Use only
Format Liquid
Concentration 200 µg/mL
Buffer PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
Background publications Cao, Henzel, Gao: "IRAK: a kinase associated with the interleukin-1 receptor." in: Science (New York, N.Y.), Vol. 271, Issue 5252, pp. 1128-31, 1996 (PubMed).

Robinson, Shibuya, Mui et al.: "IGIF does not drive Th1 development but synergizes with IL-12 for interferon-gamma production and activates IRAK and NFkappaB." in: Immunity, Vol. 7, Issue 4, pp. 571-81, 1997 (PubMed).

Huang, Gao, Li et al.: "Recruitment of IRAK to the interleukin 1 receptor complex requires interleukin 1 receptor accessory protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 24, pp. 12829-32, 1998 (PubMed).

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