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SARS-Coronavirus Membrane Protein (SARS-CoV M) (C-Term) Peptide

SARS-CoV M Reactivity: SARS Coronavirus (SARS-CoV) BP Sodium azide
Catalog No. ABIN1382275
$147.40
Plus shipping costs $50.00
0.05 mg
Shipping to: United States
Delivery in 2 to 4 Business Days

Quick Overview for SARS-Coronavirus Membrane Protein (SARS-CoV M) (C-Term) Peptide (ABIN1382275)

Target

SARS-Coronavirus Membrane Protein (SARS-CoV M)

Origin

SARS Coronavirus (SARS-CoV)

Application

Blocking Peptide (BP)
  • Protein Region

    C-Term

    Characteristics

    13 amino acids near the carboxy terminus of SARS M protein.
    Virus
  • Application Notes

    SARS matrix peptide is used for blocking the activity of the SARS matrix.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    200 μg/mL

    Buffer

    PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Expiry Date

    12 months
  • Target

    SARS-Coronavirus Membrane Protein (SARS-CoV M)

    Target Type

    Viral Protein

    Background

    Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus. The disease is the cause of the 2019–20 coronavirus outbreak. The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. The membrane (M) protein or matrix protein is the most abundant structural protein and defines the shape of the viral envelope. It is an integral membrane protein involved in the budding of the viral particles and interacts with S (Spike) protein. It involves in organization of the nucleoprotein inside, which includes many copies of the N (nucleocapsid) protein bound to the genomic RNA. The M protein holds dominant cellular immunogenicity and has been determined as a protective antigen in humoral responses, which suggests it would serve as a potential target in vaccine design.
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