Carbohydrate (N-Acetylgalactosamine 4-Sulfate 6-O) Sulfotransferase 15 (CHST15) Peptide
Quick Overview for Carbohydrate (N-Acetylgalactosamine 4-Sulfate 6-O) Sulfotransferase 15 (CHST15) Peptide (ABIN936033)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- YDNSTDGEPP FLTQDFIHAF QPNARLIVML RDPVERLYSD YLYFASSNKS
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of GALNAC4 S-4 T antibody,
Alternative Names: GALNAC4S-6ST control peptide, GALNAC4S-6ST antibody Blocking Peptide, Anti-GALNAC4S-6ST Blocking Peptide, B Cell Rag Associated Protein Blocking Peptide, BRAG Blocking Peptide, DKFZp781H1369 Blocking Peptide, KIAA0598 Blocking Peptide, MGC34346 Blocking Peptide, RP.1 Blocking Peptide, GALNAC4S, GALNACS-4, GALNACS 4, GALNACS-4 Blocking Peptide, GALNACS 4 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- CHST15 (Carbohydrate (N-Acetylgalactosamine 4-Sulfate 6-O) Sulfotransferase 15 (CHST15))
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Background
- GALNAC4S-6ST is a sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4,6-SO(4)) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc(4SO4)-GlcA(2SO4)-GalNAc(6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. GALNAC4S-6ST may also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression, however such results are unclear in vivo.
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Molecular Weight
- 65 kDa
Target
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