KH Domain Containing, RNA Binding, Signal Transduction Associated 3 (KHDRBS3) Peptide
Quick Overview for KH Domain Containing, RNA Binding, Signal Transduction Associated 3 (KHDRBS3) Peptide (ABIN938066)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- EQSYDSYDNS YSTPAQSGAD YYDYGHGLSE ETYDSYGQEE WTNSRHKAPS
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of KHDRBS3 antibody,
Alternative Names: KHDRBS3 control peptide, KHDRBS3 antibody Blocking Peptide, Anti-KHDRBS3 Blocking Peptide, Kh Domain Containing Rna Binding Signal Transduction Associated 3 Blocking Peptide, KHDRBS3, KHDRBS-3, KHDRBS 3, KHDRBS-3 Blocking Peptide, KHDRBS 3 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- KHDRBS3 (KH Domain Containing, RNA Binding, Signal Transduction Associated 3 (KHDRBS3))
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Background
- As a RNA-binding protein, KHDRBS3 plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. KHDRBS3 may play a role as a negative regulator of cell growth. It inhibits cell proliferation and involved in splice site selection of vascular endothelial growth factor. It induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. It also involved in post-transcriptional regulation of HIV-1 gene expression.
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Molecular Weight
- 38 kDa
Target
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