Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) Peptide
KPNA2
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN938988
$398.38
Plus shipping costs $50.00
100 μg
Shipping to:
United States
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Quick Overview for Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) Peptide (ABIN938988)
Target
KPNA2
(Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- GTDEQTQVVI DAGALAVFPS LLTNPKTNIQ KEATWTMSNI TAGRQDQIQQ
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of KPNA2 antibody,
Alternative Names: Karyopherin Alpha 2 control peptide, Karyopherin Alpha 2 antibody Blocking Peptide, Anti-Karyopherin Alpha 2 Blocking Peptide, IPOA1 Blocking Peptide, QIP2 Blocking Peptide, RCH1 Blocking Peptide, SRP1alpha Blocking Peptide, Rag Cohort 1 Importin Alpha 1 Blocking Peptide, KPNA2 Blocking Peptide, Karyopherin Alpha 2, Karyopherin Alpha -2, Karyopherin Alpha 2, Karyopherin Alpha -2 Blocking Peptide, Karyopherin Alpha 2 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- KPNA2 (Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2))
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Background
- Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins.
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Molecular Weight
- 58 kDa
Target
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