H2A Histone Family, Member Y (H2AFY) Peptide
Quick Overview for H2A Histone Family, Member Y (H2AFY) Peptide (ABIN939198)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- HPKYRIGVGA PVYMAAVLEY LTAEILELAG NAARDNKKGR VTPRHILLAV
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of H2 AFY antibody,
Alternative Names: H2AFY control peptide, H2AFY antibody Blocking Peptide, Anti-H2AFY Blocking Peptide, H2A Histone Y Blocking Peptide, H2A.y Blocking Peptide, H2A/y Blocking Peptide, H2AF12M Blocking Peptide, H2AFJ Blocking Peptide, MACROH2A1.1 Blocking Peptide, mH2A1 Blocking Peptide, macroH2A1.2 Blocking Peptide, H2AF, HAF-2, HAF 2, HAF-2 Blocking Peptide, HAF 2 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- H2AFY (H2A Histone Family, Member Y (H2AFY))
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Background
- Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. H2AFY is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Molecular Weight
- 39 kDa
Target
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